Revealing the pathogenic changes of PAH based on multiomics characteristics

Integrin alpha5beta1 suppresses rBMSCs anoikis and promotes nitric oxide production

(2018) Hai-ying Chen et al.   BIOMEDICINE & PHARMACOTHERAPY

Granzyme B deficiency promotes osteoblastic differentiation and calcification of vascular smooth muscle cells in hypoxic pulmonary hypertension

(2018) Min Mao et al.   Cell Death & Disease

Global Proteomics Deciphered Novel-Function of Osthole Against Pulmonary Arterial Hypertension

(2018) Li Yao et al.   Scientific Reports

Changes in gene expression profiles in patients with pulmonary arterial hypertension associated with scleroderma treated with tadalafil

(2017) Fei-Ying Cheong et al.   SEMINARS IN ARTHRITIS AND RHEUMATISM

Atropos: specific, sensitive, and speedy trimming of sequencing reads

(2017) John P. Didion et al.   PeerJ

Estrogen receptor-dependent attenuation of hypoxia-induced changes in the lung genome of pulmonary hypertension rats

(2017) Andrea L. Frump et al.   Pulmonary Circulation

Contribution of Impaired Parasympathetic Activity to Right Ventricular Dysfunction and Pulmonary Vascular Remodeling in Pulmonary Arterial Hypertension

(2017) Denielli da Silva Gonçalves Bós et al.   CIRCULATION

Análisis de la metilación de la región promotora del gen BMPR2 en pacientes con hipertensión arterial pulmonar

(2016) Guillermo Pousada et al.   ARCHIVOS DE BRONCONEUMOLOGIA

Significance of myocardial tenascin-C expression in left ventricular remodelling and long-term outcome in patients with dilated cardiomyopathy

(2016) Tetsuro Yokokawa et al.   EUROPEAN JOURNAL OF HEART FAILURE

Análisis de la metilación de la región promotora del gen BMPR2 en pacientes con hipertensión arterial pulmonar

(2016) Guillermo Pousada et al.   ARCHIVOS DE BRONCONEUMOLOGIA

RNA Sequencing Analysis Detection of a Novel Pathway of Endothelial Dysfunction in Pulmonary Arterial Hypertension

(2015) Christopher J. Rhodes et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Neural crest cell-autonomous roles of fibronectin in cardiovascular development

(2015) Xia Wang et al.   DEVELOPMENT

StringTie enables improved reconstruction of a transcriptome from RNA-seq reads

(2015) Mihaela Pertea et al.   NATURE BIOTECHNOLOGY

Ballgown bridges the gap between transcriptome assembly and expression analysis

(2015) Alyssa C Frazee et al.   NATURE BIOTECHNOLOGY

Tumor microenvironment tenascin-C promotes glioblastoma invasion and negatively regulates tumor proliferation

(2015) Shuli Xia et al.   NEURO-ONCOLOGY

Role of epigenetics in pulmonary hypertension

(2014) Tara V. Saco et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Distinct Differences in Gene Expression Patterns in Pulmonary Arteries of Patients with Chronic Obstructive Pulmonary Disease and Idiopathic Pulmonary Fibrosis with Pulmonary Hypertension

(2014) Julia Hoffmann et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Loss of Bone Morphogenetic Protein Receptor 2 Is Associated with Abnormal DNA Repair in Pulmonary Arterial Hypertension

(2014) Molong Li et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Genome-Wide Meta-Analyses of Plasma Renin Activity and Concentration Reveal Association With the Kininogen 1 and Prekallikrein GenesCLINICAL PERSPECTIVE

(2014) Wolfgang Lieb et al.   Circulation-Cardiovascular Genetics

Human cytochrome P450 epoxygenases: Variability in expression and role in inflammation-related disorders

(2014) Payman Shahabi et al.   PHARMACOLOGY & THERAPEUTICS

Systematic Analysis of Blood Cell Transcriptome in End-Stage Chronic Respiratory Diseases

(2014) Julie Chesné et al.   PLoS One

Protective Role of IL-6 in Vascular Remodeling inSchistosomaPulmonary Hypertension

(2013) Brian B. Graham et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Down-Regulation of TRPM8 in Pulmonary Arteries of Pulmonary Hypertensive Rats

(2013) Xiao-Ru Liu et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Effect of thrombomodulin on the development of monocrotaline-induced pulmonary hypertension

(2013) Yasuharu Yamada et al.   Journal of Anesthesia

Pulmonary Hypertension in Chronic Lung Diseases

(2013) Werner Seeger et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Proteomic Analysis Reveals that Proteasome Subunit Beta 6 Is Involved in Hypoxia-Induced Pulmonary Vascular Remodeling in Rats

(2013) Jian Wang et al.   PLoS One

A Reference Methylome Database and Analysis Pipeline to Facilitate Integrative and Comparative Epigenomics

(2013) Qiang Song et al.   PLoS One

A Genome-Wide Association Study Identifies KNG1 as a Genetic Determinant of Plasma Factor XI Level and Activated Partial Thromboplastin Time

(2012) Maria Sabater-Lleal et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Pulmonary arteriole gene expression signature in idiopathic pulmonary fibrosis

(2012) Nina M. Patel et al.   EUROPEAN RESPIRATORY JOURNAL

Gene expression analysis of a murine model with pulmonary vascular remodeling compared to end-stage IPAH lungs

(2012) Kayoko Shimodaira et al.   RESPIRATORY RESEARCH

methylKit: a comprehensive R package for the analysis of genome-wide DNA methylation profiles

(2012) Altuna Akalin et al.   GENOME BIOLOGY

Key Role of 15-Lipoxygenase/15-Hydroxyeicosatetraenoic Acid in Pulmonary Vascular Remodeling and Vascular Angiogenesis Associated With Hypoxic Pulmonary Hypertension

(2011) Cui Ma et al.   HYPERTENSION

Global quantification of mammalian gene expression control

(2011) Björn Schwanhäusser et al.   NATURE

Transcriptomic Analysis Identifies Phosphatases as Novel Targets for Adenotonsillar Hypertrophy of Pediatric Obstructive Sleep Apnea

(2010) Abdelnaby Khalyfa et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Proteomic Analysis of Lung Tissues From Patients With Pulmonary Arterial Hypertension

(2010) Vahitha B. Abdul-Salam et al.   CIRCULATION

Mast cells promote lung vascular remodelling in pulmonary hypertension

(2010) J. Hoffmann et al.   EUROPEAN RESPIRATORY JOURNAL

The Sequence Alignment/Map format and SAMtools

(2009) H. Li et al.   BIOINFORMATICS

COL4A1 Is Associated With Arterial Stiffness by Genome-Wide Association Scan

(2009) Kirill V. Tarasov et al.   Circulation-Cardiovascular Genetics

The Noncanonical WNT Pathway Is Operative in Idiopathic Pulmonary Arterial Hypertension

(2008) Isabel P. Laumanns et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY