Loss of Bone Morphogenetic Protein Receptor 2 Is Associated with Abnormal DNA Repair in Pulmonary Arterial Hypertension

Oxidative Injury is a Common Consequence of BMPR2 Mutations

(2014) Kirk L. Lane et al.   Pulmonary Circulation

Combined Treatment With Peroxisome Proliferator-Activated Receptor (PPAR) Gamma Ligands and Gamma Radiation Induces Apoptosis by PPARγ-Independent Up-Regulation of Reactive Oxygen Species-Induced Deoxyribonucleic Acid Damage Signals in Non-Small Cell Lung Cancer Cells

(2013) Eun Jong Han et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Atypical Atm–p53 genetic interaction in osteogenesis is mediated by Smad1 signaling

(2012) Gang Ma et al.   Journal of Molecular Cell Biology

A crucial role for bone morphogenetic protein-Smad1 signalling in the DNA damage response

(2012) Jenny Fung Ling Chau et al.   Nature Communications

BMPR2 expression is suppressed by signaling through the estrogen receptor

(2012) Eric D Austin et al.   Biology of Sex Differences

Disruption of PPARγ/β-catenin–mediated regulation of apelin impairs BMP-induced mouse and human pulmonary arterial EC survival

(2011) Tero-Pekka Alastalo et al.   JOURNAL OF CLINICAL INVESTIGATION

Disruption of bone morphogenetic protein receptor 2 (BMPR2) in mammary tumors promotes metastases through cell autonomous and paracrine mediators

(2011) P. Owens et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genomewide RNA expression profiling in lung identifies distinct signatures in idiopathic pulmonary arterial hypertension and secondary pulmonary hypertension

(2010) Revathi Rajkumar et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Somatic Chromosome Abnormalities in the Lungs of Patients with Pulmonary Arterial Hypertension

(2010) Micheala A. Aldred et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

DNA repair signature is associated with anthracycline response in triple negative breast cancer patients

(2010) A. A. Rodriguez et al.   BREAST CANCER RESEARCH AND TREATMENT

Cancer cell mitochondria confer apoptosis resistance and promote metastasis

(2010) Mariola Kulawiec et al.   CANCER BIOLOGY & THERAPY

NKX3.1 Activates Cellular Response to DNA Damage

(2010) C. Bowen et al.   CANCER RESEARCH

Transcriptional Autoregulation by BRCA1

(2010) A. De Siervi et al.   CANCER RESEARCH

Defective pulmonary vascular remodeling in Smad8 mutant mice

(2009) Z. Huang et al.   HUMAN MOLECULAR GENETICS

Bone morphogenetic protein 2 induces pulmonary angiogenesis via Wnt–β-catenin and Wnt–RhoA–Rac1 pathways

(2009) Vinicio A. de Jesus Perez et al.   JOURNAL OF CELL BIOLOGY

A new nonsense mutation of SMAD8 associated with pulmonary arterial hypertension

(2009) M Shintani et al.   JOURNAL OF MEDICAL GENETICS

BRCA1 Interacts with Smad3 and Regulates Smad3-Mediated TGF-β Signaling during Oxidative Stress Responses

(2009) Huchun Li et al.   PLoS One

The Cancer Paradigm of Severe Pulmonary Arterial Hypertension

(2008) Pradeep R. Rai et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

The Bone Morphogenetic Protein Pathway Is Inactivated in the Majority of Sporadic Colorectal Cancers

(2008) Liudmila L. Kodach et al.   GASTROENTEROLOGY

An antiproliferative BMP-2/PPARγ/apoE axis in human and murine SMCs and its role in pulmonary hypertension

(2008) Georg Hansmann et al.   JOURNAL OF CLINICAL INVESTIGATION