Phosphorylation in two discrete tau domains regulates a stepwise process leading to postsynaptic dysfunction

Tau-mediated synaptic and neuronal dysfunction in neurodegenerative disease

(2018) Tara E Tracy et al.   CURRENT OPINION IN NEUROBIOLOGY

Synaptogyrin-3 Mediates Presynaptic Dysfunction Induced by Tau

(2018) Joseph McInnes et al.   NEURON

Distinct phenotypes of three-repeat and four-repeat human tau in a transgenic model of tauopathy

(2017) Megan A. Sealey et al.   NEUROBIOLOGY OF DISEASE

Tau association with synaptic vesicles causes presynaptic dysfunction

(2017) Lujia Zhou et al.   Nature Communications

Bidirectional interplay of HSF1 degradation and UPR activation promotes tau hyperphosphorylation

(2017) Eunhee Kim et al.   PLoS Genetics

FLEXITau: Quantifying Post-translational Modifications of Tau Protein in Vitro and in Human Disease

(2016) Waltraud Mair et al.   ANALYTICAL CHEMISTRY

Soluble Conformers of A  and Tau Alter Selective Proteins Governing Axonal Transport

(2016) M. A. Sherman et al.   JOURNAL OF NEUROSCIENCE

HSF1 critically attunes proteotoxic stress sensing by mTORC1 to combat stress and promote growth

(2016) Kuo-Hui Su et al.   NATURE CELL BIOLOGY

Caspase-2 cleavage of tau reversibly impairs memory

(2016) Xiaohui Zhao et al.   NATURE MEDICINE

Acetylated Tau Obstructs KIBRA-Mediated Signaling in Synaptic Plasticity and Promotes Tauopathy-Related Memory Loss

(2016) Tara E. Tracy et al.   NEURON

NMDA Receptor-Dependent LTD Requires Transient Synaptic Incorporation of Ca 2+ -Permeable AMPARs Mediated by AKAP150-Anchored PKA and Calcineurin

(2016) Jennifer L. Sanderson et al.   NEURON

Human iPSC-Derived Neuronal Model of Tau-A152T Frontotemporal Dementia Reveals Tau-Mediated Mechanisms of Neuronal Vulnerability

(2016) M. Catarina Silva et al.   Stem Cell Reports

Clinical Features of Repetitive Traumatic Brain Injury and Chronic Traumatic Encephalopathy

(2015) Philip H. Montenigro et al.   BRAIN PATHOLOGY

SIL1 Rescued Bip Elevation-Related Tau Hyperphosphorylation in ER Stress

(2015) Zan-Chao Liu et al.   MOLECULAR NEUROBIOLOGY

Invited review: Frontotemporal dementia caused bymicrotubule-associated protein taugene (MAPT) mutations: a chameleon for neuropathology and neuroimaging

(2015) Bernardino Ghetti et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Tau phosphorylation and tau mislocalization mediate soluble Aβ oligomer-induced AMPA glutamate receptor signaling deficits

(2014) Eric C. Miller et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Axonal Transport: Cargo-Specific Mechanisms of Motility and Regulation

(2014) Sandra Maday et al.   NEURON

Lost after translation: missorting of Tau protein and consequences for Alzheimer disease

(2014) Hans Zempel et al.   TRENDS IN NEUROSCIENCES

Physiological and pathological phosphorylation of tau by Cdk5

(2014) Taeko Kimura et al.   Frontiers in Molecular Neuroscience

Protein phosphorylation in neurodegeneration: friend or foe?

(2014) Sandra Tenreiro et al.   Frontiers in Molecular Neuroscience

Deregulated Cdk5 Activity Is Involved in Inducing Alzheimer’s Disease

(2012) Varsha Shukla et al.   ARCHIVES OF MEDICAL RESEARCH

Stages of the Pathologic Process in Alzheimer Disease: Age Categories From 1 to 100 Years

(2011) Heiko Braak et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

AMPA receptor subunit GluR1 (GluA1) serine-845 site is involved in synaptic depression but not in spine shrinkage associated with chemical long-term depression

(2011) Kaiwen He et al.   JOURNAL OF NEUROPHYSIOLOGY

Tau-Induced Defects in Synaptic Plasticity, Learning, and Memory Are Reversible in Transgenic Mice after Switching Off the Toxic Tau Mutant

(2011) A. Sydow et al.   JOURNAL OF NEUROSCIENCE

Novel screening cascade identifies MKK4 as key kinase regulating Tau phosphorylation at Ser422

(2011) Fiona Grueninger et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Tau oligomers impair memory and induce synaptic and mitochondrial dysfunction in wild-type mice

(2011) Cristian A Lasagna-Reeves et al.   Molecular Neurodegeneration

Dendritic Function of Tau Mediates Amyloid-β Toxicity in Alzheimer's Disease Mouse Models

(2010) Lars M. Ittner et al.   CELL

Morphine Induces AMPA Receptor Internalization in Primary Hippocampal Neurons via Calcineurin-Dependent Dephosphorylation of GluR1 Subunits

(2010) A. Y. F. Kam et al.   JOURNAL OF NEUROSCIENCE

Acetylation of Tau Inhibits Its Degradation and Contributes to Tauopathy

(2010) Sang-Won Min et al.   NEURON

Tau Mislocalization to Dendritic Spines Mediates Synaptic Dysfunction Independently of Neurodegeneration

(2010) Brian R. Hoover et al.   NEURON

Chronic Traumatic Encephalopathy in Athletes: Progressive Tauopathy After Repetitive Head Injury

(2009) Ann C. McKee et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Tau binds both subunits of calcineurin, and binding is impaired by calmodulin

(2008) Da-yu Yu et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH