Cutting Edge: Tcf1 Instructs T Follicular Helper Cell Differentiation by Repressing Blimp1 in Response to Acute Viral Infection

Tcf1 and Lef1 are required for the immunosuppressive function of regulatory T cells

(2019) Shaojun Xing et al.   JOURNAL OF EXPERIMENTAL MEDICINE

T follicular helper cell heterogeneity: Time, space, and function

(2019) Wenzhi Song et al.   IMMUNOLOGICAL REVIEWS

The Role of WNT Signaling in Mature T Cells: T Cell Factor Is Coming Home

(2018) Jorg van Loosdregt et al.   JOURNAL OF IMMUNOLOGY

Ezh2 programs TFH differentiation by integrating phosphorylation-dependent activation of Bcl6 and polycomb-dependent repression of p19Arf

(2018) Fengyin Li et al.   Nature Communications

Differential Requirements for Tcf1 Long Isoforms in CD8+and CD4+T Cell Responses to Acute Viral Infection

(2017) Jodi A. Gullicksrud et al.   JOURNAL OF IMMUNOLOGY

Transcription Factor T-bet Orchestrates Lineage Development and Function in the Immune System

(2017) Axel Kallies et al.   TRENDS IN IMMUNOLOGY

Follicular Helper T Cells

(2016) Carola G. Vinuesa et al.   Annual Review of Immunology

CD4+T cell effector commitment coupled to self-renewal by asymmetric cell divisions

(2016) Simone A. Nish et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Id2 reinforces TH1 differentiation and inhibits E2A to repress TFH differentiation

(2016) Laura A Shaw et al.   NATURE IMMUNOLOGY

Tcf1 and Lef1 transcription factors establish CD8+ T cell identity through intrinsic HDAC activity

(2016) Shaojun Xing et al.   NATURE IMMUNOLOGY

BCL6 orchestrates Tfh cell differentiation via multiple distinct mechanisms

(2015) Katerina Hatzi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The transcription factor TCF-1 initiates the differentiation of TFH cells during acute viral infection

(2015) Lifan Xu et al.   NATURE IMMUNOLOGY

LEF-1 and TCF-1 orchestrate TFH differentiation by regulating differentiation circuits upstream of the transcriptional repressor Bcl6

(2015) Youn Soo Choi et al.   NATURE IMMUNOLOGY

TCF1 Is Required for the T Follicular Helper Cell Response to Viral Infection

(2015) Tuoqi Wu et al.   Cell Reports

From inception to output, Tcf1 and Lef1 safeguard development of T cells and innate immune cells

(2014) Farrah C. Steinke et al.   IMMUNOLOGIC RESEARCH

TCF-1 and LEF-1 act upstream of Th-POK to promote the CD4+ T cell fate and interact with Runx3 to silence Cd4 in CD8+ T cells

(2014) Farrah C Steinke et al.   NATURE IMMUNOLOGY

Regulation of mature T cell responses by the Wnt signaling pathway

(2012) Hai-Hui Xue et al.   Annals of the New York Academy of Sciences

ICOS Receptor Instructs T Follicular Helper Cell versus Effector Cell Differentiation via Induction of the Transcriptional Repressor Bcl6

(2011) Youn Soo Choi et al.   IMMUNITY

The Transcriptional Repressor Bcl-6 Directs T Follicular Helper Cell Lineage Commitment

(2009) Di Yu et al.   IMMUNITY

Bcl6 and Blimp-1 Are Reciprocal and Antagonistic Regulators of T Follicular Helper Cell Differentiation

(2009) R. J. Johnston et al.   SCIENCE

Bcl6 Mediates the Development of T Follicular Helper Cells

(2009) R. I. Nurieva et al.   SCIENCE