CD4+T cell effector commitment coupled to self-renewal by asymmetric cell divisions

T Cell Factor 1-Expressing Memory-like CD8 + T Cells Sustain the Immune Response to Chronic Viral Infections

(2016) Daniel T. Utzschneider et al.   IMMUNITY

Follicular CXCR5-expressing CD8+ T cells curtail chronic viral infection

(2016) Ran He et al.   NATURE

Metabolic maintenance of cell asymmetry following division in activated T lymphocytes

(2016) Katherine C. Verbist et al.   NATURE

Defining CD8+ T cells that provide the proliferative burst after PD-1 therapy

(2016) Se Jin Im et al.   NATURE

Plasma cell differentiation is coupled to division-dependent DNA hypomethylation and gene regulation

(2016) Benjamin G Barwick et al.   NATURE IMMUNOLOGY

Asymmetric inheritance of mTORC1 kinase activity during division dictates CD8+ T cell differentiation

(2016) Kristen N Pollizzi et al.   NATURE IMMUNOLOGY

CXCR5+ follicular cytotoxic T cells control viral infection in B cell follicles

(2016) Yew Ann Leong et al.   NATURE IMMUNOLOGY

De novo DNA methylation by DNA methyltransferase 3a controls early effector CD8+T-cell fate decisions following activation

(2016) Brian H. Ladle et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Most microbe-specific naive CD4+ T cells produce memory cells during infection

(2016) N. J. Tubo et al.   SCIENCE

The Interleukin-2-mTORc1 Kinase Axis Defines the Signaling, Differentiation, and Metabolism of T Helper 1 and Follicular B Helper T Cells

(2015) John P. Ray et al.   IMMUNITY

T Follicular Helper Cells Have Distinct Modes of Migration and Molecular Signatures in Naive and Memory Immune Responses

(2015) Dan Suan et al.   IMMUNITY

The transcription factor TCF-1 initiates the differentiation of TFH cells during acute viral infection

(2015) Lifan Xu et al.   NATURE IMMUNOLOGY

LEF-1 and TCF-1 orchestrate TFH differentiation by regulating differentiation circuits upstream of the transcriptional repressor Bcl6

(2015) Youn Soo Choi et al.   NATURE IMMUNOLOGY

Apoptosis and antigen affinity limit effector cell differentiation of a single naive B cell

(2015) J. J. Taylor et al.   SCIENCE

Cell-Cycle-Dependent Reconfiguration of the DNA Methylome during Terminal Differentiation of Human B Cells into Plasma Cells

(2015) Gersende Caron et al.   Cell Reports

TCF1 Is Required for the T Follicular Helper Cell Response to Viral Infection

(2015) Tuoqi Wu et al.   Cell Reports

Asymmetric PI3K Signaling Driving Developmental and Regenerative Cell Fate Bifurcation

(2015) Wen-Hsuan W. Lin et al.   Cell Reports

Serial Transfer of Single-Cell-Derived Immunocompetence Reveals Stemness of CD8+ Central Memory T Cells

(2014) Patricia Graef et al.   IMMUNITY

T Cell Factor 1 Represses CD8+Effector T Cell Formation and Function

(2014) Machteld M. Tiemessen et al.   JOURNAL OF IMMUNOLOGY

Functional heterogeneity of human memory CD4+ T cell clones primed by pathogens or vaccines

(2014) S. Becattini et al.   SCIENCE

Single Naive CD4+ T Cells from a Diverse Repertoire Produce Different Effector Cell Types during Infection

(2013) Noah J. Tubo et al.   CELL

Transcriptional regulation of effector and memory CD8+ T cell fates

(2013) James ED Thaventhiran et al.   CURRENT OPINION IN IMMUNOLOGY

Environmental Cues Dictate the Fate of Individual CD8+ T Cells Responding to Infection

(2013) Courtney R. Plumlee et al.   IMMUNITY

Distinct Memory CD4+ T Cells with Commitment to T Follicular Helper- and T Helper 1-Cell Lineages Are Generated after Acute Viral Infection

(2013) J. Scott Hale et al.   IMMUNITY

Global DNA Methylation Remodeling Accompanies CD8 T Cell Effector Function

(2013) C. D. Scharer et al.   JOURNAL OF IMMUNOLOGY

Bcl6 Expressing Follicular Helper CD4 T Cells Are Fate Committed Early and Have the Capacity To Form Memory

(2013) Y. S. Choi et al.   JOURNAL OF IMMUNOLOGY

DNMT1 Is Regulated by ATP-Citrate Lyase and Maintains Methylation Patterns during Adipocyte Differentiation

(2013) T. Londono Gentile et al.   MOLECULAR AND CELLULAR BIOLOGY

Disparate Individual Fates Compose Robust CD8+ T Cell Immunity

(2013) V. R. Buchholz et al.   SCIENCE

Heterogeneous Differentiation Patterns of Individual CD8+ T Cells

(2013) C. Gerlach et al.   SCIENCE

Metabolic Regulation of Epigenetics

(2012) Chao Lu et al.   Cell Metabolism

Cutting Edge: Asymmetric Memory T Cell Division in Response to Rechallenge

(2012) M. L. Ciocca et al.   JOURNAL OF IMMUNOLOGY

Opposing Signals from the Bcl6 Transcription Factor and the Interleukin-2 Receptor Generate T Helper 1 Central and Effector Memory Cells

(2011) Marion Pepper et al.   IMMUNITY

A critical role for TCF-1 in T-lineage specification and differentiation

(2011) Brittany Nicole Weber et al.   NATURE

T-cell factor 1 is a gatekeeper for T-cell specification in response to Notch signaling

(2011) K. Germar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Asymmetric B Cell Division in the Germinal Center Reaction

(2011) B. E. Barnett et al.   SCIENCE

Differentiation of Effector CD4 T Cell Populations

(2010) Jinfang Zhu et al.   Annual Review of Immunology

Development and Migration of Plasma Cells in the Mouse Lymph Node

(2010) David R. Fooksman et al.   IMMUNITY

Differentiation and Persistence of Memory CD8+ T Cells Depend on T Cell Factor 1

(2010) Xinyuan Zhou et al.   IMMUNITY

One naive T cell, multiple fates in CD8+T cell differentiation

(2010) Carmen Gerlach et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The Early Generation of a Heterogeneous CD4+ T Cell Response to Leishmania major

(2010) S. L. Colpitts et al.   JOURNAL OF IMMUNOLOGY

Essential role of the Wnt pathway effector Tcf-1 for the establishment of functional CD8 T cell memory

(2010) G. Jeannet et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Constitutive Activation of Wnt Signaling Favors Generation of Memory CD8 T Cells

(2009) D.-M. Zhao et al.   JOURNAL OF IMMUNOLOGY