Differential Requirements for Tcf1 Long Isoforms in CD8+and CD4+T Cell Responses to Acute Viral Infection

Cutting Edge: β-Catenin–Interacting Tcf1 Isoforms Are Essential for Thymocyte Survival but Dispensable for Thymic Maturation Transitions

(2017) Zhe Xu et al.   JOURNAL OF IMMUNOLOGY

CD4+T cell effector commitment coupled to self-renewal by asymmetric cell divisions

(2016) Simone A. Nish et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A molecular threshold for effector CD8+ T cell differentiation controlled by transcription factors Blimp-1 and T-bet

(2016) Annie Xin et al.   NATURE IMMUNOLOGY

Id2 reinforces TH1 differentiation and inhibits E2A to repress TFH differentiation

(2016) Laura A Shaw et al.   NATURE IMMUNOLOGY

Tcf1 and Lef1 transcription factors establish CD8+ T cell identity through intrinsic HDAC activity

(2016) Shaojun Xing et al.   NATURE IMMUNOLOGY

Most microbe-specific naive CD4+ T cells produce memory cells during infection

(2016) N. J. Tubo et al.   SCIENCE

CD8 + T Lymphocyte Self-Renewal during Effector Cell Determination

(2016) Wen-Hsuan W. Lin et al.   Cell Reports

BCL6 orchestrates Tfh cell differentiation via multiple distinct mechanisms

(2015) Katerina Hatzi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The transcription factor TCF-1 initiates the differentiation of TFH cells during acute viral infection

(2015) Lifan Xu et al.   NATURE IMMUNOLOGY

TCF-1 upregulation identifies early innate lymphoid progenitors in the bone marrow

(2015) Qi Yang et al.   NATURE IMMUNOLOGY

LEF-1 and TCF-1 orchestrate TFH differentiation by regulating differentiation circuits upstream of the transcriptional repressor Bcl6

(2015) Youn Soo Choi et al.   NATURE IMMUNOLOGY

TCF1 Is Required for the T Follicular Helper Cell Response to Viral Infection

(2015) Tuoqi Wu et al.   Cell Reports

Asymmetric PI3K Signaling Driving Developmental and Regenerative Cell Fate Bifurcation

(2015) Wen-Hsuan W. Lin et al.   Cell Reports

T Follicular Helper Cell Differentiation, Function, and Roles in Disease

(2014) Shane Crotty   IMMUNITY

From inception to output, Tcf1 and Lef1 safeguard development of T cells and innate immune cells

(2014) Farrah C. Steinke et al.   IMMUNOLOGIC RESEARCH

TCF-1 and LEF-1 act upstream of Th-POK to promote the CD4+ T cell fate and interact with Runx3 to silence Cd4 in CD8+ T cells

(2014) Farrah C Steinke et al.   NATURE IMMUNOLOGY

Molecular regulation of effector and memory T cell differentiation

(2014) John T Chang et al.   NATURE IMMUNOLOGY

Single Naive CD4+ T Cells from a Diverse Repertoire Produce Different Effector Cell Types during Infection

(2013) Noah J. Tubo et al.   CELL

Distinct Memory CD4+ T Cells with Commitment to T Follicular Helper- and T Helper 1-Cell Lineages Are Generated after Acute Viral Infection

(2013) J. Scott Hale et al.   IMMUNITY

Regulation of mature T cell responses by the Wnt signaling pathway

(2012) Hai-Hui Xue et al.   Annals of the New York Academy of Sciences

Bcl6 and Maf Cooperate To Instruct Human Follicular Helper CD4 T Cell Differentiation

(2012) M. A. Kroenke et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: Generation of Memory Precursors and Functional Memory CD8+ T Cells Depends on T Cell Factor-1 and Lymphoid Enhancer-Binding Factor-1

(2012) X. Zhou et al.   JOURNAL OF IMMUNOLOGY

The transcriptional regulators Id2 and Id3 control the formation of distinct memory CD8+ T cell subsets

(2011) Cliff Y Yang et al.   NATURE IMMUNOLOGY

Differentiation of Effector CD4 T Cell Populations

(2010) Jinfang Zhu et al.   Annual Review of Immunology

Differentiation and Persistence of Memory CD8+ T Cells Depend on T Cell Factor 1

(2010) Xinyuan Zhou et al.   IMMUNITY

Cutting Edge: The Transcription Factor Eomesodermin Enables CD8+ T Cells To Compete for the Memory Cell Niche

(2010) A. Banerjee et al.   JOURNAL OF IMMUNOLOGY

Essential role of the Wnt pathway effector Tcf-1 for the establishment of functional CD8 T cell memory

(2010) G. Jeannet et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Constitutive Activation of Wnt Signaling Favors Generation of Memory CD8 T Cells

(2009) D.-M. Zhao et al.   JOURNAL OF IMMUNOLOGY

T cell factor 1 initiates the T helper type 2 fate by inducing the transcription factor GATA-3 and repressing interferon-γ

(2009) Qing Yu et al.   NATURE IMMUNOLOGY

Bcl6 and Blimp-1 Are Reciprocal and Antagonistic Regulators of T Follicular Helper Cell Differentiation

(2009) R. J. Johnston et al.   SCIENCE

The canonical Wnt signaling pathway plays an important role in lymphopoiesis and hematopoiesis

(2008) Frank J. T. Staal et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Rapid Culling of the CD4+ T Cell Repertoire in the Transition from Effector to Memory

(2008) Matthew A. Williams et al.   IMMUNITY

The costimulatory molecule ICOS regulates the expression of c-Maf and IL-21 in the development of follicular T helper cells and TH-17 cells

(2008) Aurelie T Bauquet et al.   NATURE IMMUNOLOGY