Proximal Lck Promoter–Driven Cre Function Is Limited in Neonatal and Ineffective in Adult γδ T Cell Development

The Emerging Complexity of γδT17 Cells

(2018) Duncan R. McKenzie et al.   Frontiers in Immunology

Downregulation of E Protein Activity Augments an ILC2 Differentiation Program in the Thymus

(2017) Hong-Cheng Wang et al.   JOURNAL OF IMMUNOLOGY

Thymic Determinants of γδ T Cell Differentiation

(2017) Miguel Muñoz-Ruiz et al.   TRENDS IN IMMUNOLOGY

Three distinct developmental pathways for adaptive and two IFN-γ-producing γδ T subsets in adult thymus

(2017) Terkild Brink Buus et al.   Nature Communications

Strong TCRγδ Signaling Prohibits Thymic Development of IL-17A-Secreting γδ T Cells

(2017) Nital Sumaria et al.   Cell Reports

T-cell development is regulated by the coordinated function of proximal and distal Lck promoters active at different developmental stages

(2016) Y. Jeffrey Chiang et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

lck-Driven Cre Expression Alters T Cell Development in the Thymus and the Frequencies and Functions of Peripheral T Cell Subsets

(2016) Berit Carow et al.   JOURNAL OF IMMUNOLOGY

TCR signal strength controls thymic differentiation of discrete proinflammatory γδ T cell subsets

(2016) Miguel Muñoz-Ruiz et al.   NATURE IMMUNOLOGY

Differential Requirements of TCR Signaling in Homeostatic Maintenance and Function of Dendritic Epidermal T Cells

(2015) Baojun Zhang et al.   JOURNAL OF IMMUNOLOGY

Heme Exporter FLVCR Is Required for T Cell Development and Peripheral Survival

(2015) Mary Philip et al.   JOURNAL OF IMMUNOLOGY

The burgeoning family of unconventional T cells

(2015) Dale I Godfrey et al.   NATURE IMMUNOLOGY

hCD2-iCre and Vav-iCre Mediated Gene Recombination Patterns in Murine Hematopoietic Cells

(2015) Sabine Siegemund et al.   PLoS One

The TCR ligand-inducible expression of CD73 marks γδ lineage commitment and a metastable intermediate in effector specification

(2014) Francis Coffey et al.   JOURNAL OF EXPERIMENTAL MEDICINE

IFN- -Producing and IL-17-Producing    T Cells Differentiate at Distinct Developmental Stages in Murine Fetal Thymus

(2014) K. Shibata et al.   JOURNAL OF IMMUNOLOGY

Origins of γδ T Cell Effector Subsets: A Riddle Wrapped in an Enigma

(2014) Shawn P. Fahl et al.   JOURNAL OF IMMUNOLOGY

T-cell activation by transitory neo-antigens derived from distinct microbial pathways

(2014) Alexandra J. Corbett et al.   NATURE

Conformational changes in the T cell receptor differentially determine T cell subset development in mice

(2014) R. Blanco et al.   Science Signaling

FADD regulates thymocyte development at the β-selection checkpoint by modulating Notch signaling

(2014) X Zhang et al.   Cell Death & Disease

Differential developmental requirement and peripheral regulation for dermal Vγ4 and Vγ6T17 cells in health and inflammation

(2014) Yihua Cai et al.   Nature Communications

Functional development of γδ T cells

(2013) Immo Prinz et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

In vivo fate mapping identifies pre-TCRα expression as an intra- and extrathymic, but not prethymic, marker of T lymphopoiesis

(2013) Hervé Luche et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Combined Deletion of Id2 and Id3 Genes Reveals Multiple Roles for E Proteins in Invariant NKT Cell Development and Expansion

(2013) J. Li et al.   JOURNAL OF IMMUNOLOGY

Development of Interleukin-17-Producing γδ T Cells Is Restricted to a Functional Embryonic Wave

(2012) Jan D. Haas et al.   IMMUNITY

Activation Kinetics and Off-Target Effects of Thymus-Initiated Cre Transgenes

(2012) Jianjun Shi et al.   PLoS One

Kidins220/ARMS mediates the integration of the neurotrophin and VEGF pathways in the vascular and nervous systems

(2011) F Cesca et al.   CELL DEATH AND DIFFERENTIATION

Cutaneous immunosurveillance by self-renewing dermal γδ T cells

(2011) Nital Sumaria et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Aryl Hydrocarbon Receptor Is Critical for Homeostasis of Invariant    T Cells in the Murine Epidermis

(2011) S. Kadow et al.   JOURNAL OF IMMUNOLOGY

The Transcription Factor PU.1 Regulates γδ T Cell Homeostasis

(2011) Rukhsana Jabeen et al.   PLoS One

Bcl11b represses a mature T-cell gene expression program in immature CD4+CD8+ thymocytes

(2010) Philippe Kastner et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Elevated mitochondrial superoxide disrupts normal T cell development, impairing adaptive immune responses to an influenza challenge

(2010) Adam J. Case et al.   FREE RADICAL BIOLOGY AND MEDICINE

CCR6 and NK1.1 distinguish between IL-17A and IFN-γ-producing γδ effector T cells

(2009) Jan D. Haas et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

NKAP Is a Transcriptional Repressor of Notch Signaling and Is Required for T Cell Development

(2009) Anthony G. Pajerowski et al.   IMMUNITY

CD27 is a thymic determinant of the balance between interferon-γ- and interleukin 17–producing γδ T cell subsets

(2009) Julie C Ribot et al.   NATURE IMMUNOLOGY

A robust and high-throughput Cre reporting and characterization system for the whole mouse brain

(2009) Linda Madisen et al.   NATURE NEUROSCIENCE

Essential role of Rap signal in pre-TCR-mediated  -selection checkpoint in    T-cell development

(2008) K. Kometani et al.   BLOOD

CTCF regulates cell cycle progression of αβ T cells in the thymus

(2008) Helen Heath et al.   EMBO JOURNAL

Thymic Selection Determines γδ T Cell Effector Fate: Antigen-Naive Cells Make Interleukin-17 and Antigen-Experienced Cells Make Interferon γ

(2008) Kirk D.C. Jensen et al.   IMMUNITY

ADAM10 is essential for proteolytic activation of Notch during thymocyte development

(2008) L. Tian et al.   INTERNATIONAL IMMUNOLOGY