Functional and mechanistic studies reveal MAGEA3 as a pro-survival factor in pancreatic cancer cells

The perfect personalized cancer therapy: cancer vaccines against neoantigens

(2018) Luigi Aurisicchio et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Induction of antitumor cytotoxic lymphocytes using engineered human primary blood dendritic cells

(2018) Long Wu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TRIM16 controls assembly and degradation of protein aggregates by modulating the p62‐NRF2 axis and autophagy

(2018) Kautilya Kumar Jena et al.   EMBO JOURNAL

Role of anlotinib-induced CCL2 decrease in anti-angiogenesis and response prediction for non-small cell lung cancer therapy

(2018) Jun Lu et al.   EUROPEAN RESPIRATORY JOURNAL

Increased Serotonin Signaling Contributes to the Warburg Effect in Pancreatic Tumor Cells Under Metabolic Stress and Promotes Growth of Pancreatic Tumors in Mice

(2017) Shu-Heng Jiang et al.   GASTROENTEROLOGY

Circulating tumor cell as a biomarker for evaluating allogenic NK cell immunotherapy on stage IV non-small cell lung cancer

(2017) Mao Lin et al.   IMMUNOLOGY LETTERS

Personalized ex vivo multiple peptide enrichment and detection of T cells reactive to multiple tumor-associated antigens in prostate cancer patients

(2017) Pavla Taborska et al.   MEDICAL ONCOLOGY

MAGE-TRIM28 complex promotes the Warburg effect and hepatocellular carcinoma progression by targeting FBP1 for degradation

(2017) X Jin et al.   Oncogenesis

The Emerging Hallmarks of Cancer Metabolism

(2016) Natalya N. Pavlova et al.   Cell Metabolism

Systematic identification of genes with a cancer-testis expression pattern in 19 cancer types

(2016) Cheng Wang et al.   Nature Communications

Functional annotation of rare gene aberration drivers of pancreatic cancer

(2016) Yiu Huen Tsang et al.   Nature Communications

Characterization and use of HapT1-derived homologous tumors as a preclinical model to evaluate therapeutic efficacy of drugs against pancreatic tumor desmoplasia

(2016) Sujit Suklabaidya et al.   Oncotarget

Targeting the CCL2-CCR2 signaling axis in cancer metastasis

(2016) Su Yin Lim et al.   Oncotarget

The Magea gene cluster regulates male germ cell apoptosis without affecting the fertility in mice

(2016) Siyuan Hou et al.   Scientific Reports

Oncogenic MAGEA-TRIM28 ubiquitin ligase downregulates autophagy by ubiquitinating and degrading AMPK in cancer

(2015) Carlos T Pineda et al.   Autophagy

Therapeutic Targeting of the Warburg Effect in Pancreatic Cancer Relies on an Absence of p53 Function

(2015) N. V. Rajeshkumar et al.   CANCER RESEARCH

Degradation of AMPK by a Cancer-Specific Ubiquitin Ligase

(2015) Carlos T. Pineda et al.   CELL

TRIM proteins legitimately enter the MAGEic RING

(2015) Melania E Zanchetta et al.   CELL CYCLE

Tumor Metabolism: MAGE-A Proteins Help TRIM Turn Over AMPK

(2015) Reuben J. Shaw   CURRENT BIOLOGY

Whole genomes redefine the mutational landscape of pancreatic cancer

(2015) Nicola Waddell et al.   NATURE

Novel cancer antigens for personalized immunotherapies: latest evidence and clinical potential

(2015) Gregory T. Wurz et al.   Therapeutic Advances in Medical Oncology

CCL2 Is a Negative Regulator of AMP-Activated Protein Kinase to Sustain mTOR Complex-1 Activation, Survivin Expression, and Cell Survival in Human Prostate Cancer PC3 Cells

(2015) Hernan Roca et al.   NEOPLASIA

MAGE proteins regulate KRAB zinc finger transcription factors and KAP1 E3 ligase activity

(2014) Tony Z. Xiao et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

CCL2, survivin and autophagy: New links with implications in human cancer

(2014) Hernan Roca et al.   Autophagy

Pancreatic cell plasticity and cancer initiation induced by oncogenic Kras is completely dependent on wild-type PI 3-kinase p110α

(2014) Romain Baer et al.   GENES & DEVELOPMENT

Chemokines in Cancer Development and Progression and Their Potential as Targeting Molecules for Cancer Treatment

(2014) Naofumi Mukaida et al.   MEDIATORS OF INFLAMMATION

The Chemokine (CCL2–CCR2) Signaling Axis Mediates Perineural Invasion

(2014) Shizhi He et al.   MOLECULAR CANCER RESEARCH

Cessation of CCL2 inhibition accelerates breast cancer metastasis by promoting angiogenesis

(2014) Laura Bonapace et al.   NATURE

Isolation, culture and genetic manipulation of mouse pancreatic ductal cells

(2013) Maximilian Reichert et al.   Nature Protocols

Ectopic Activation of Germline and Placental Genes Identifies Aggressive Metastasis-Prone Lung Cancers

(2013) S. Rousseaux et al.   Science Translational Medicine

Tumor-specific MAGE proteins as regulators of p53 function

(2012) María Fátima Ladelfa et al.   CANCER LETTERS

MAGE-A antigens as targets in tumour therapy

(2012) David W. Meek et al.   CANCER LETTERS

Autophagy and cell growth - the yin and yang of nutrient responses

(2012) T. P. Neufeld   JOURNAL OF CELL SCIENCE

Metastatic Pancreatic Cancer Is Dependent on Oncogenic Kras in Mice

(2012) Meredith A. Collins et al.   PLoS One

Targeting the MAGE A3 antigen in pancreatic cancer

(2012) Alexandria P. Cogdill et al.   SURGERY

Identification of novel small molecules that inhibit protein–protein interactions between MAGE and KAP-1

(2011) Neehar Bhatia et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

MAGE-A Inhibits Apoptosis in Proliferating Myeloma Cells through Repression of Bax and Maintenance of Survivin

(2011) T. Nardiello et al.   CLINICAL CANCER RESEARCH

Potential targets for pancreatic cancer immunotherapeutics

(2011) Lindzy F Dodson et al.   Immunotherapy

The biology of cancer testis antigens: Putative function, regulation and therapeutic potential

(2011) Elisabetta Fratta et al.   Molecular Oncology

Nutrient starvation elicits an acute autophagic response mediated by Ulk1 dephosphorylation and its subsequent dissociation from AMPK

(2011) L. Shang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MAGE A3 antigen-specific cancer immunotherapeutic

(2010) Nir Peled et al.   Immunotherapy

miR-34a confers chemosensitivity through modulation of MAGE-A and p53 in medulloblastoma

(2010) Shyamal D. Weeraratne et al.   NEURO-ONCOLOGY

Phenotype and Genotype of Pancreatic Cancer Cell Lines

(2010) Emily L. Deer et al.   PANCREAS

Chemokines and chemokine receptors: new insights into cancer-related inflammation

(2010) Gwendal Lazennec et al.   TRENDS IN MOLECULAR MEDICINE

Hypoxia Induced Tumor Metabolic Switch Contributes to Pancreatic Cancer Aggressiveness

(2010) Sophie Vasseur et al.   Cancers

Autophagy: Not good OR bad, but good AND bad

(2009) Brian J. Altman et al.   Autophagy

Cancer-testis antigens MAGE-C1/CT7 and MAGE-A3 promote the survival of multiple myeloma cells

(2009) D. Atanackovic et al.   HAEMATOLOGICA

A Versatile Viral System for Expression and Depletion of Proteins in Mammalian Cells

(2009) Eric Campeau et al.   PLoS One

Analysis of expression profiles of MAGE-A antigens in oral squamous cell carcinoma cell lines

(2009) Urs DA Müller-Richter et al.   Head & Face Medicine

The Melanoma-Associated Antigen A3 Mediates Fibronectin-Controlled Cancer Progression and Metastasis

(2008) W. Liu et al.   CANCER RESEARCH

Fibroblast Growth Factor 2 and Estrogen Control the Balance of Histone 3 Modifications Targeting MAGE-A3 in Pituitary Neoplasia

(2008) X. Zhu et al.   CLINICAL CANCER RESEARCH

CCL2 Protects Prostate Cancer PC3 Cells from Autophagic Death via Phosphatidylinositol 3-Kinase/AKT-dependent Survivin Up-regulation

(2008) Hernan Roca et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Role of the Tumor Microenvironment in the Progression of Pancreatic Cancer

(2008) Buckminster Farrow et al.   JOURNAL OF SURGICAL RESEARCH

Booster vaccination of cancer patients with MAGE-A3 protein reveals long-term immunological memory or tolerance depending on priming

(2008) D. Atanackovic et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA