Centaurea cyanus extracted 13‐O‐acetylsolstitialin A decrease Bax/Bcl‐2 ratio and expression of cyclin D1/Cdk‐4 to induce apoptosis and cell cycle arrest in MCF‐7 and MDA‐MB‐231 breast cancer cell lines

Cancer statistics, 2018

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A2a adenosine receptor agonist improves endoplasmic reticulum stress in MIN6 cell line through protein kinase A/ protein kinase B/ Cyclic adenosine monophosphate response element-binding protein/ and Growth Arrest And DNA-Damage-Inducible 34/ eukaryotic I

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Chemical features and bioactivities of cornflower (Centaurea cyanus L.) capitula: The blue flowers and the unexplored non-edible part

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A2B adenosine receptor agonist induces cell cycle arrest and apoptosis in breast cancer stem cells via ERK1/2 phosphorylation

(2017) Seyyed Mehdi Jafari et al.   CELLULAR ONCOLOGY

Sinuleptolide inhibits proliferation of oral cancer Ca9-22 cells involving apoptosis, oxidative stress, and DNA damage

(2016) Yung-Ting Chang et al.   ARCHIVES OF ORAL BIOLOGY

Natural Products as Sources of New Drugs from 1981 to 2014

(2016) David J. Newman et al.   JOURNAL OF NATURAL PRODUCTS

Mitochondrial apoptosis: killing cancer using the enemy within

(2015) J Lopez et al.   BRITISH JOURNAL OF CANCER

Apigenin, a dietary flavonoid, inhibits proliferation of human bladder cancer T-24 cells via blocking cell cycle progression and inducing apoptosis

(2015) Ming-Der Shi et al.   Cancer Cell International

Molecular mechanism of apoptosis induction by Gaillardin, a sesquiterpene lactone, in breast cancer cell lines

(2015) Faranak Fallahian et al.   CELL BIOLOGY AND TOXICOLOGY

The role of oxidative stress in anticancer activity of sesquiterpene lactones

(2015) Katarzyna Gach et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

The differential susceptibilities of MCF-7 and MDA-MB-231 cells to the cytotoxic effects of curcumin are associated with the PI3K/Akt-SKP2-Cip/Kips pathway

(2014) Tao Jia et al.   Cancer Cell International

Cancer incidence and mortality worldwide: Sources, methods and major patterns in GLOBOCAN 2012

(2014) Jacques Ferlay et al.   INTERNATIONAL JOURNAL OF CANCER

Past, Present, and Future Challenges in Breast Cancer Treatment

(2014) George W. Sledge et al.   JOURNAL OF CLINICAL ONCOLOGY

Secondary metabolites of three endemic Centaurea L. species

(2014) Vele Tesevic et al.   JOURNAL OF THE SERBIAN CHEMICAL SOCIETY

Britannin, a sesquiterpene lactone, inhibits proliferation and induces apoptosis through the mitochondrial signaling pathway in human breast cancer cells

(2014) Maryam Hamzeloo-Moghadam et al.   TUMOR BIOLOGY

5-epi-Sinuleptolide induces cell cycle arrest and apoptosis through tumor necrosis factor/mitochondria-mediated caspase signaling pathway in human skin cancer cells

(2012) Chia-Hua Liang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

What made sesquiterpene lactones reach cancer clinical trials?

(2010) Akram Ghantous et al.   DRUG DISCOVERY TODAY

Centchroman induces G0/G1 arrest and Caspase-dependent Apoptosis involving Mitochondrial Membrane Depolarization in MCF-7 and MDA MB-231 Human Breast Cancer Cells

(2008) Manisha Nigam et al.   LIFE SCIENCES