Air Pollution, Combustion and Friction Derived Nanoparticles, and Alzheimer’s Disease in Urban Children and Young Adults

Longitudinal tau accumulation and atrophy in aging and alzheimer disease

(2019) Theresa M. Harrison et al.   ANNALS OF NEUROLOGY

Natural, incidental, and engineered nanomaterials and their impacts on the Earth system

(2019) Michael F. Hochella et al.   SCIENCE

Tau seeding activity begins in the transentorhinal/entorhinal regions and anticipates phospho-tau pathology in Alzheimer’s disease and PART

(2018) Sarah K. Kaufman et al.   ACTA NEUROPATHOLOGICA

NIA-AA Research Framework: Toward a biological definition of Alzheimer's disease

(2018) Clifford R. Jack et al.   Alzheimers & Dementia

Depression and Risk of Alzheimer's Dementia: A Longitudinal Analysis to Determine Predictors of Increased Risk among Older Adults with Depression

(2018) Damien Gallagher et al.   AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY

Hallmarks of Alzheimer disease are evolving relentlessly in Metropolitan Mexico City infants, children and young adults. APOE4 carriers have higher suicide risk and higher odds of reaching NFT stage V at ≤ 40 years of age

(2018) Lilian Calderón-Garcidueñas et al.   ENVIRONMENTAL RESEARCH

Alzheimer's disease and alpha-synuclein pathology in the olfactory bulbs of infants, children, teens and adults ≤ 40 years in Metropolitan Mexico City. APOE4 carriers at higher risk of suicide accelerate their olfactory bulb pathology

(2018) Lilian Calderón-Garcidueñas et al.   ENVIRONMENTAL RESEARCH

Impact of nanoparticles on neuron biology: current research trends

(2018) Firdos Khan et al.   International Journal of Nanomedicine

Violence rife in Mexico, affecting medical community

(2018) David Agren   LANCET

Ambient air pollution and completed suicide in 26 South Korean cities: Effect modification by demographic and socioeconomic factors

(2018) Hyewon Lee et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Vital Signs: Trends in State Suicide Rates — United States, 1999–2016 and Circumstances Contributing to Suicide — 27 States, 2015

(2018) Deborah M. Stone et al.   MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT

Absolute 10-year risk of dementia by age, sex andAPOEgenotype: a population-based cohort study

(2018) Katrine L. Rasmussen et al.   CANADIAN MEDICAL ASSOCIATION JOURNAL

Traffic-Related Air Pollution, APOE ε4 Status, and Neurodevelopmental Outcomes among School Children Enrolled in the BREATHE Project (Catalonia, Spain)

(2018) Silvia Alemany et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Titanium dioxide nanoparticles induce mouse hippocampal neuron apoptosis via oxidative stress- and calcium imbalance-mediated endoplasmic reticulum stress

(2018) Qiong He et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Neuroinflammation, Hyperphosphorylated Tau, Diffuse Amyloid Plaques, and Down-Regulation of the Cellular Prion Protein in Air Pollution Exposed Children and Young Adults

(2018) Lilian Calderón-Garcidueñas et al.   JOURNAL OF ALZHEIMERS DISEASE

Interest of neuroimaging of social exclusion in suicide

(2018) Emilie Olié et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Prévention du suicide et santé connectée

(2018) Sofian Berrouiguet et al.   M S-MEDECINE SCIENCES

New classification of tauopathies

(2018) G.U. Höglinger et al.   REVUE NEUROLOGIQUE

Long-term occupational trajectories and suicide: a 22-year follow-up of the GAZEL cohort study

(2018) Marine Azevedo Da Silva et al.   SCANDINAVIAN JOURNAL OF WORK ENVIRONMENT & HEALTH

Incidence of female suicide in New York City: how important are socioeconomic factors?

(2018) Bonu Sengupta et al.   SOCIAL PSYCHIATRY AND PSYCHIATRIC EPIDEMIOLOGY

Distribution of magnetic remanence carriers in the human brain

(2018) Stuart A. Gilder et al.   Scientific Reports

Electromagnetic Regulation of Cell Activity

(2018) Sarah A. Stanley et al.   Cold Spring Harbor Perspectives in Medicine

Blood-Cerebrospinal Fluid Barrier Gradients in Mild Cognitive Impairment and Alzheimer's Disease: Relationship to Inflammatory Cytokines and Chemokines

(2018) Brian R. Ott et al.   Frontiers in Aging Neuroscience

Assessing Risk of Future Suicidality in Emergency Department Patients

(2018) Krista Brucker et al.   ACADEMIC EMERGENCY MEDICINE

Emergency Department Presentations and Youth Suicide: A Case-Control Study

(2018) Anne E. Rhodes et al.   CANADIAN JOURNAL OF PSYCHIATRY-REVUE CANADIENNE DE PSYCHIATRIE

The Role of APOE and TREM2 in Alzheimer′s Disease—Current Understanding and Perspectives

(2018) Cody Wolfe et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The Synergistic Effects of APOE Genotype and Obesity on Alzheimer’s Disease Risk

(2018) Nahdia Jones et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Non-Phosphorylated Tau in Cerebrospinal Fluid is a Marker of Alzheimer’s Disease Continuum in Young Urbanites Exposed to Air Pollution

(2018) Lilian Calderón-Garcidueñas et al.   JOURNAL OF ALZHEIMERS DISEASE

The association between PM2.5 exposure and neurological disorders: A systematic review and meta-analysis

(2018) Pengfei Fu et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Combustion-derived nanoparticles, the neuroenteric system, cervical vagus, hyperphosphorylated alpha synuclein and tau in young Mexico City residents

(2017) Lilian Calderón-Garcidueñas et al.   ENVIRONMENTAL RESEARCH

Does air pollution trigger suicide? A case-crossover analysis of suicide deaths over the life span

(2017) Lidia Casas et al.   EUROPEAN JOURNAL OF EPIDEMIOLOGY

Mitochondrial dysfunction underlies cognitive defects as a result of neural stem cell depletion and impaired neurogenesis

(2017) Mireille Khacho et al.   HUMAN MOLECULAR GENETICS

Combustion-Derived Nanoparticles in Key Brain Target Cells and Organelles in Young Urbanites: Culprit Hidden in Plain Sight in Alzheimer’s Disease Development

(2017) Angélica González-Maciel et al.   JOURNAL OF ALZHEIMERS DISEASE

The role of APOE on lipid homeostasis and inflammation in normal brains

(2017) G. William Rebeck   JOURNAL OF LIPID RESEARCH

Living near major roads and the incidence of dementia, Parkinson's disease, and multiple sclerosis: a population-based cohort study

(2017) Hong Chen et al.   LANCET

Precision medicine for suicidality: from universality to subtypes and personalization

(2017) A B Niculescu et al.   MOLECULAR PSYCHIATRY

The Neurovascular Unit Coming of Age: A Journey through Neurovascular Coupling in Health and Disease

(2017) Costantino Iadecola   NEURON

Traffic is a major source of atmospheric nanocluster aerosol

(2017) Topi Rönkkö et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Prospective associations of exercise and depressive symptoms in older adults: the role of apolipoprotein E4

(2017) Po-Wen Ku et al.   QUALITY OF LIFE RESEARCH

Effects of silica nanoparticle exposure on mitochondrial function during neuronal differentiation

(2017) Angélique D. Ducray et al.   JOURNAL OF NANOBIOTECHNOLOGY

Preclinical Alzheimer's disease: Definition, natural history, and diagnostic criteria

(2016) Bruno Dubois et al.   Alzheimers & Dementia

Mitochondrial traffic jams in Alzheimer's disease - pinpointing the roadblocks

(2016) Sónia C. Correia et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Interactive and additive influences of Gender, BMI and Apolipoprotein 4 on cognition in children chronically exposed to high concentrations of PM2.5 and ozone. APOE 4 females are at highest risk in Mexico City

(2016) Lilian Calderón-Garcidueñas et al.   ENVIRONMENTAL RESEARCH

Prefrontal white matter pathology in air pollution exposed Mexico City young urbanites and their potential impact on neurovascular unit dysfunction and the development of Alzheimer's disease

(2016) Lilian Calderón-Garcidueñas et al.   ENVIRONMENTAL RESEARCH

Insulin resistance, dyslipidemia, and apolipoprotein E interactions as mechanisms in cognitive impairment and Alzheimer's disease

(2016) Therese S Salameh et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Size-dependent cytotoxicity of Fe3O4 nanoparticles induced by biphasic regulation of oxidative stress in different human hepatoma cells

(2016) Pei Feng Liu et al.   International Journal of Nanomedicine

Ambient air pollution and suicide in Tokyo, 2001–2011

(2016) Chris Fook Sheng Ng et al.   JOURNAL OF AFFECTIVE DISORDERS

Cerebrospinal Fluid Biomarkers in Highly Exposed PM2.5 Urbanites: The Risk of Alzheimer’s and Parkinson’s Diseases in Young Mexico City Residents

(2016) Lilian Calderón-Garcidueñas et al.   JOURNAL OF ALZHEIMERS DISEASE

Longitudinal association of obesity, metabolic syndrome and diabetes with risk of elevated aminotransferase levels in a cohort of Mexican health workers

(2016) Yvonne N. Flores et al.   Journal of Digestive Diseases

Mexico's epidemic of violence and its public health significance on average length of life

(2016) Vladimir Canudas-Romo et al.   JOURNAL OF EPIDEMIOLOGY AND COMMUNITY HEALTH

Timing of Physical Activity, Apolipoprotein Eε4 Genotype, and Risk of Incident Mild Cognitive Impairment

(2016) Janina Krell-Roesch et al.   JOURNAL OF THE AMERICAN GERIATRICS SOCIETY

The adaptive immune system restrains Alzheimer’s disease pathogenesis by modulating microglial function

(2016) Samuel E. Marsh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Magnetite pollution nanoparticles in the human brain

(2016) Barbara A. Maher et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Association of Higher Cortical Amyloid Burden With Loneliness in Cognitively Normal Older Adults

(2016) Nancy J. Donovan et al.   JAMA Psychiatry

Acute Air Pollution Exposure and Risk of Suicide Completion

(2015) A. V. Bakian et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

The preclinical phase of the pathological process underlying sporadic Alzheimer’s disease

(2015) Heiko Braak et al.   BRAIN

External magnetic fields affect the biological impacts of superparamagnetic iron nanoparticles

(2015) Saeed Shanehsazzadeh et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Mexico City normal weight children exposed to high concentrations of ambient PM2.5 show high blood leptin and endothelin-1, vitamin D deficiency, and food reward hormone dysregulation versus low pollution controls. Relevance for obesity and Alzheimer disease

(2015) Lilian Calderón-Garcidueñas et al.   ENVIRONMENTAL RESEARCH

Urban air pollution, poverty, violence and health – Neurological and immunological aspects as mediating factors

(2015) Marianne Kristiansson et al.   ENVIRONMENTAL RESEARCH

Cerebrovascular and mitochondrial abnormalities in Alzheimer’s disease: a brief overview

(2015) Cristina Carvalho et al.   JOURNAL OF NEURAL TRANSMISSION

Expression of Regulatory Proteins in Choroid Plexus Changes in Early Stages of Alzheimer Disease

(2015) Agnieszka Krzyzanowska et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Understanding and predicting suicidality using a combined genomic and clinical risk assessment approach

(2015) A B Niculescu et al.   MOLECULAR PSYCHIATRY

Invited review: Neuropathology of tauopathies: principles and practice

(2015) G. G. Kovacs   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Gold Nanoparticles Increase Endothelial Paracellular Permeability by Altering Components of Endothelial Tight Junctions, and Increase Blood-Brain Barrier Permeability in Mice

(2015) Ching-Hao Li et al.   TOXICOLOGICAL SCIENCES

Amyloid biomarkers in Alzheimer's disease

(2015) Kaj Blennow et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Choroid plexus dysfunction impairs beta-amyloid clearance in a triple transgenic mouse model of Alzheimer’s disease

(2015) Ibrahim González-Marrero et al.   Frontiers in Cellular Neuroscience

APOE ε4: The most prevalent yet understudied risk factor for Alzheimer's disease

(2014) Daniel M. Michaelson   Alzheimers & Dementia

Apolipoprotein E: Structure and function in lipid metabolism, neurobiology, and Alzheimer's diseases

(2014) Yadong Huang et al.   NEUROBIOLOGY OF DISEASE

Uptake and Metabolism of Iron Oxide Nanoparticles in Brain Cells

(2014) Charlotte Petters et al.   NEUROCHEMICAL RESEARCH

Carbonaceous Aerosols in Fine Particulate Matter of Santiago Metropolitan Area, Chile

(2014) Richard Toro Araya et al.   TheScientificWorldJOURNAL

20-Year prevalence projections for dementia and impact of preventive policy about risk factors

(2013) Hélène Jacqmin-Gadda et al.   EUROPEAN JOURNAL OF EPIDEMIOLOGY

Brain Differences in Infants at Differential Genetic Risk for Late-Onset Alzheimer Disease

(2013) Douglas C. Dean et al.   JAMA Neurology

Brain immune interactions and air pollution: macrophage inhibitory factor (MIF), prion cellular protein (PrPC), Interleukin-6 (IL-6), interleukin 1 receptor antagonist (IL-1Ra), and interleukin-2 (IL-2) in cerebrospinal fluid and MIF in serum differentiate urban children exposed to severe vs. low air pollution

(2013) Lilian Calderón-Garcidueñas et al.   Frontiers in Neuroscience

PM2.5 mass and species trends in Santiago, Chile, 1998 to 2010: The impact of fuel-related interventions and fuel sales

(2012) Iny Jhun et al.   JOURNAL OF THE AIR & WASTE MANAGEMENT ASSOCIATION

Air quality progress in North American megacities: A review

(2011) David D. Parrish et al.   ATMOSPHERIC ENVIRONMENT

Concentrations and properties of airborne particles in the Mexico City subway system

(2011) V. Mugica-Álvarez et al.   ATMOSPHERIC ENVIRONMENT

Exposure to severe urban air pollution influences cognitive outcomes, brain volume and systemic inflammation in clinically healthy children

(2011) Lilian Calderón-Garcidueñas et al.   BRAIN AND COGNITION

Apolipoprotein E isoforms and regulation of the innate immune response in brain of patients with Alzheimer's disease

(2011) C Dirk Keene et al.   CURRENT OPINION IN NEUROBIOLOGY

Stages of the Pathologic Process in Alzheimer Disease: Age Categories From 1 to 100 Years

(2011) Heiko Braak et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Ambient Particulate Matter as a Risk Factor for Suicide

(2010) Changsoo Kim et al.   AMERICAN JOURNAL OF PSYCHIATRY

Hosted and Free-Floating Metal-Bearing Atmospheric Nanoparticles in Mexico City

(2010) Kouji Adachi et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Nuclear Tau, a Key Player in Neuronal DNA Protection

(2010) Audrey Sultan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Trigeminal Pathways Deliver a Low Molecular Weight Drug from the Nose to the Brain and Orofacial Structures

(2010) Neil J. Johnson et al.   MOLECULAR PHARMACEUTICS

Urban air pollution: Influences on olfactory function and pathology in exposed children and young adults

(2009) Lilian Calderón-Garcidueñas et al.   EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY

Apolipoprotein E4 Domain Interaction Induces Endoplasmic Reticulum Stress and Impairs Astrocyte Function

(2009) Ning Zhong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Systemic inflammation and disease progression in Alzheimer disease

(2009) C. Holmes et al.   NEUROLOGY

Cognitive reserve☆

(2009) Yaakov Stern   NEUROPSYCHOLOGIA

Air pollution, cognitive deficits and brain abnormalities: A pilot study with children and dogs

(2008) Lilian Calderón-Garcidueñas et al.   BRAIN AND COGNITION

Systemic Inflammation, Endothelial Dysfunction, and Activation in Clinically Healthy Children Exposed to Air Pollutants

(2008) L. Calderón-Garcidueñas et al.   INHALATION TOXICOLOGY

Neurodevelopmental Trajectories of the Human Cerebral Cortex

(2008) P. Shaw et al.   JOURNAL OF NEUROSCIENCE

Long-term Air Pollution Exposure Is Associated with Neuroinflammation, an Altered Innate Immune Response, Disruption of the Blood-Brain Barrier, Ultrafine Particulate Deposition, and Accumulation of Amyloid β-42 and α-Synuclein in Children and Young Adults

(2008) Lilian Calderón-Garcidueñas et al.   TOXICOLOGIC PATHOLOGY