Serum Insulin-Like Growth Factor I Deficiency Associates to Alzheimer’s Disease Co-Morbidities

Circulating insulin-like growth factor I modulates mood and is a biomarker of vulnerability to stress: from mouse to man

(2018) A. Santi et al.   Translational Psychiatry

Exercise-linked FNDC5/irisin rescues synaptic plasticity and memory defects in Alzheimer’s models

(2018) Mychael V. Lourenco et al.   NATURE MEDICINE

Neuropsychiatric symptoms predict hypometabolism in preclinical Alzheimer disease

(2017) Kok Pin Ng et al.   NEUROLOGY

Low serum insulin-like growth factor-I (IGF-I) level is associated with increased risk of vascular dementia

(2017) Patrick Quinlan et al.   PSYCHONEUROENDOCRINOLOGY

Insulin-like growth factor-1: a possible marker for emotional and cognitive disturbances, and treatment effectiveness in major depressive disorder

(2017) Oleg A. Levada et al.   Annals of General Psychiatry

IGF-1 has sexually dimorphic, pleiotropic, and time-dependent effects on healthspan, pathology, and lifespan

(2017) Nicole M. Ashpole et al.   GeroScience

Incidence and impact of subclinical epileptiform activity in Alzheimer's disease

(2016) Keith A. Vossel et al.   ANNALS OF NEUROLOGY

Sleep extension increases IGF-I concentrations before and during sleep deprivation in healthy young men

(2016) Mounir Chennaoui et al.   Applied Physiology Nutrition and Metabolism

FNDC5 relates to skeletal muscle IGF-I and mitochondrial function and gene expression in obese men with reduced growth hormone

(2016) Suman Srinivasa et al.   GROWTH HORMONE & IGF RESEARCH

Low Serum Insulin-Like Growth Factor-I Predicts Cognitive Decline in Alzheimer’s Disease

(2016) Jean-Sébastien Vidal et al.   JOURNAL OF ALZHEIMERS DISEASE

Human Cortical Neural Stem Cells Expressing Insulin-Like Growth Factor-I: A Novel Cellular Therapy for Alzheimer's Disease

(2016) Lisa M. McGinley et al.   Stem Cells Translational Medicine

Insulin-like growth factor 1 and risk of depression in older people: the English Longitudinal Study of Ageing

(2016) S Chigogora et al.   Translational Psychiatry

Insulin-Like Growth Factor 1 (IGF-1) in Parkinson's Disease: Potential as Trait-, Progression- and Prediction Marker and Confounding Factors

(2016) Felix P. Bernhard et al.   PLoS One

Meta-Analysis of Serum Insulin-Like Growth Factor 1 in Alzheimer’s Disease

(2016) Philip P. Ostrowski et al.   PLoS One

Blocking IGF Signaling in Adult Neurons Alleviates Alzheimer's Disease Pathology through Amyloid-β Clearance

(2015) Géraldine Gontier et al.   JOURNAL OF NEUROSCIENCE

Hippocampal insulin resistance and cognitive dysfunction

(2015) Geert Jan Biessels et al.   NATURE REVIEWS NEUROSCIENCE

Serum insulin-like growth factor-I and amyloid beta protein in Alzheimer's disease: relationship with cognitive function

(2015) Ayako Kimoto et al.   Psychogeriatrics

Serum insulin-like growth factor-I and amyloid beta protein in Alzheimer's disease: relationship with cognitive function

(2015) Ayako Kimoto et al.   Psychogeriatrics

Insulin-like growth factor-1 and risk of Alzheimer dementia and brain atrophy

(2014) A. J. Westwood et al.   NEUROLOGY

A novel inhibitor of the insulin/IGF signaling pathway protects from age-onset, neurodegeneration-linked proteotoxicity

(2013) Tayir El-Ami et al.   AGING CELL

Serum but not cerebrospinal fluid levels of insulin-like growth factor-I (IGF-I) and IGF-binding protein-3 (IGFBP-3) are increased in Alzheimer's disease

(2013) Per Johansson et al.   PSYCHONEUROENDOCRINOLOGY

Loss of serum IGF-I input to the brain as an early biomarker of disease onset in Alzheimer mice

(2013) A Trueba-Sáiz et al.   Translational Psychiatry

Insulin-Like Growth Factor-I and Insulin-Like Growth Factor Binding Protein-3 in Alzheimer's Disease

(2012) Emmanuelle Duron et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

The many faces of insulin-like peptide signalling in the brain

(2012) Ana M. Fernandez et al.   NATURE REVIEWS NEUROSCIENCE

Early brain amyloidosis in APP/PS1 mice with serum insulin-like growth factor-I deficiency

(2012) R. Poirier et al.   NEUROSCIENCE LETTERS

Sex-Dependent Alterations in Social Behaviour and Cortical Synaptic Activity Coincide at Different Ages in a Model of Alzheimer’s Disease

(2012) Cyril Bories et al.   PLoS One

Serum insulin like growth factor-1 is associated with working memory, executive function and selective attention in a sample of healthy, fit older adults

(2011) D. Bellar et al.   NEUROSCIENCE

Assessment of Social Interaction Behaviors

(2011) Oksana Kaidanovich-Beilin et al.   Jove-Journal of Visualized Experiments

Associative Learning and CA3-CA1 Synaptic Plasticity Are Impaired in D1R Null, Drd1a-/- Mice and in Hippocampal siRNA Silenced Drd1a Mice

(2010) O. Ortiz et al.   JOURNAL OF NEUROSCIENCE

Molecular Evolution and Functional Characterization of Drosophila Insulin-Like Peptides

(2010) Sebastian Grönke et al.   PLoS Genetics

Insulin like growth factor-1 and insulin like growth factor binding proteins in the cerebrospinal fluid and serum from patients with Alzheimer's disease

(2009) Zivar Salehi et al.   BIOFACTORS

The insulin paradox: aging, proteotoxicity and neurodegeneration

(2008) Ehud Cohen et al.   NATURE REVIEWS NEUROSCIENCE

Social participation in home-living patients with mild Alzheimer's disease

(2007) Lisbeth Villemoes Sørensen et al.   ARCHIVES OF GERONTOLOGY AND GERIATRICS

The effects of exercise on spatial learning and anxiety-like behavior are mediated by an IGF-I-dependent mechanism related to hippocampal neurogenesis

(2007) J.L. Trejo et al.   MOLECULAR AND CELLULAR NEUROSCIENCE