Abundance of d ‐2‐hydroxyglutarate in G2/M is determined by FOXM1 in mutant IDH1‐expressing cells
Published 2019 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Abundance of
d
‐2‐hydroxyglutarate in G2/M is determined by FOXM1 in mutant IDH1‐expressing cells
Authors
Keywords
-
Journal
FEBS LETTERS
Volume -, Issue -, Pages -
Publisher
Wiley
Online
2019-06-19
DOI
10.1002/1873-3468.13500
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Biological Role and Therapeutic Potential of IDH Mutations in Cancer
- (2018) Matthew S. Waitkus et al. CANCER CELL
- IDH1-mutant cancer cells are sensitive to cisplatin and an IDH1-mutant inhibitor counteracts this sensitivity
- (2018) Mohammed Khurshed et al. FASEB JOURNAL
- Role of Forkhead Box O (FOXO) transcription factor in aging and diseases
- (2018) Neelam Tia et al. GENE
- UPLC–MS/MS quantitative analysis and structural fragmentation study of five Parmotrema lichens from the Eastern Ghats
- (2018) K. Kumar et al. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
- SREBPs in Lipid Metabolism, Insulin Signaling, and Beyond
- (2018) Russell A. DeBose-Boyd et al. TRENDS IN BIOCHEMICAL SCIENCES
- Consumption of NADPH for 2-HG Synthesis Increases Pentose Phosphate Pathway Flux and Sensitizes Cells to Oxidative Stress
- (2018) Susan J. Gelman et al. Cell Reports
- Regulation of the master regulator FOXM1 in cancer
- (2018) Guo-Bin Liao et al. Cell Communication and Signaling
- Optineurin promotes autophagosome formation by recruiting the autophagy-related Atg12-5-16L1 complex to phagophores containing the Wipi2 protein
- (2017) Megha Bansal et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- L-2-Hydroxyglutarate production arises from noncanonical enzyme function at acidic pH
- (2017) Andrew M Intlekofer et al. Nature Chemical Biology
- Oncogenic Activities of IDH1/2 Mutations: From Epigenetics to Cellular Signaling
- (2017) Laurence M. Gagné et al. TRENDS IN CELL BIOLOGY
- AG-221, a First-in-Class Therapy Targeting Acute Myeloid Leukemia Harboring Oncogenic IDH2 Mutations
- (2017) Katharine Yen et al. Cancer Discovery
- The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary
- (2016) David N. Louis et al. ACTA NEUROPATHOLOGICA
- Sterol Regulatory Element Binding Protein Regulates the Expression and Metabolic Functions of Wild-Type and OncogenicIDH1
- (2016) Stéphane J. H. Ricoult et al. MOLECULAR AND CELLULAR BIOLOGY
- Transcriptional and post-transcriptional limitations of high-yielding, PEI-mediated transient transfection with CHO and HEK-293E cells
- (2015) Yashas Rajendra et al. BIOTECHNOLOGY PROGRESS
- Extreme Vulnerability of IDH1 Mutant Cancers to NAD+ Depletion
- (2015) Kensuke Tateishi et al. CANCER CELL
- IDH1, a CHOP and C/EBPβ-responsive gene under ER stress, sensitizes human melanoma cells to hypoxia-induced apoptosis
- (2015) Xuejun Yang et al. CANCER LETTERS
- Radioprotection of IDH1-Mutated Cancer Cells by the IDH1-Mutant Inhibitor AGI-5198
- (2015) R. J. Molenaar et al. CANCER RESEARCH
- MYC Disrupts the Circadian Clock and Metabolism in Cancer Cells
- (2015) Brian J. Altman et al. Cell Metabolism
- Hypoxia Induces Production of L-2-Hydroxyglutarate
- (2015) Andrew M. Intlekofer et al. Cell Metabolism
- Hypoxia-Mediated Increases in l -2-hydroxyglutarate Coordinate the Metabolic Response to Reductive Stress
- (2015) William M. Oldham et al. Cell Metabolism
- FOXOs support the metabolic requirements of normal and tumor cells by promoting IDH1 expression
- (2015) P. Charitou et al. EMBO REPORTS
- Integrated genomic characterization of IDH1-mutant glioma malignant progression
- (2015) Hanwen Bai et al. NATURE GENETICS
- Treatment with a Small Molecule Mutant IDH1 Inhibitor Suppresses Tumorigenic Activity and Decreases Production of the Oncometabolite 2-Hydroxyglutarate in Human Chondrosarcoma Cells
- (2015) Luyuan Li et al. PLoS One
- IDH1 Mutations Alter Citric Acid Cycle Metabolism and Increase Dependence on Oxidative Mitochondrial Metabolism
- (2014) A. R. Grassian et al. CANCER RESEARCH
- Regulation of PSMB5 Protein and β Subunits of Mammalian Proteasome by Constitutively Activated Signal Transducer and Activator of Transcription 3 (STAT3)
- (2014) Janakiram Reddy Vangala et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Improved vectors and genome-wide libraries for CRISPR screening
- (2014) Neville E Sanjana et al. NATURE METHODS
- The CHR site: definition and genome-wide identification of a cell cycle transcriptional element
- (2014) Gerd A. Müller et al. NUCLEIC ACIDS RESEARCH
- Aberrant IDH3α expression promotes malignant tumor growth by inducing HIF-1-mediated metabolic reprogramming and angiogenesis
- (2014) L Zeng et al. ONCOGENE
- Suppression of the FOXM1 transcriptional programme via novel small molecule inhibition
- (2014) Michael V. Gormally et al. Nature Communications
- Isocitrate dehydrogenase 1 mutant R132H sensitizes glioma cells to BCNU-induced oxidative stress and cell death
- (2013) Isabelle Vanessa Mohrenz et al. APOPTOSIS
- Inhibition of FOXM1 transcription factor suppresses cell proliferation and tumor growth of breast cancer
- (2013) C Yang et al. CANCER GENE THERAPY
- Identification of cell cycle–regulated genes periodically expressed in U2OS cells and their regulation by FOXM1 and E2F transcription factors
- (2013) Gavin D. Grant et al. MOLECULAR BIOLOGY OF THE CELL
- PKM2 Regulates Chromosome Segregation and Mitosis Progression of Tumor Cells
- (2013) Yuhui Jiang et al. MOLECULAR CELL
- BCAT1 promotes cell proliferation through amino acid catabolism in gliomas carrying wild-type IDH1
- (2013) Martje Tönjes et al. NATURE MEDICINE
- An Inhibitor of Mutant IDH1 Delays Growth and Promotes Differentiation of Glioma Cells
- (2013) D. Rohle et al. SCIENCE
- Targeted Inhibition of Mutant IDH2 in Leukemia Cells Induces Cellular Differentiation
- (2013) F. Wang et al. SCIENCE
- Genome-Scale CRISPR-Cas9 Knockout Screening in Human Cells
- (2013) Ophir Shalem et al. SCIENCE
- Histone H3 phosphorylation – A versatile chromatin modification for different occasions
- (2012) Anna Sawicka et al. BIOCHIMIE
- The MuvB complex sequentially recruits B-Myb and FoxM1 to promote mitotic gene expression
- (2012) S. Sadasivam et al. GENES & DEVELOPMENT
- Adenovirus-mediated RNA interference targeting FOXM1 transcription factor suppresses cell proliferation and tumor growth of nasopharyngeal carcinoma
- (2012) Hui Chen et al. JOURNAL OF GENE MEDICINE
- Overexpression of isocitrate dehydrogenase mutant proteins renders glioma cells more sensitive to radiation
- (2012) Sichen Li et al. NEURO-ONCOLOGY
- Oncometabolite 2-Hydroxyglutarate Is a Competitive Inhibitor of α-Ketoglutarate-Dependent Dioxygenases
- (2011) Wei Xu et al. CANCER CELL
- The oncometabolite 2-hydroxyglutarate inhibits histone lysine demethylases
- (2011) Rasheduzzaman Chowdhury et al. EMBO REPORTS
- The transcription factor FOXM1 is a cellular target of the natural product thiostrepton
- (2011) Nagaratna S. Hegde et al. Nature Chemistry
- Ollier disease and Maffucci syndrome are caused by somatic mosaic mutations of IDH1 and IDH2
- (2011) M Fernanda Amary et al. NATURE GENETICS
- The CHR promoter element controls cell cycle-dependent gene transcription and binds the DREAM and MMB complexes
- (2011) Gerd A. Müller et al. NUCLEIC ACIDS RESEARCH
- Frequent Mutation of Isocitrate Dehydrogenase (IDH)1 and IDH2 in Cholangiocarcinoma Identified Through Broad-Based Tumor Genotyping
- (2011) D. R. Borger et al. ONCOLOGIST
- Molecular basis for the differential use of glucose and glutamine in cell proliferation as revealed by synchronized HeLa cells
- (2011) S. L. Colombo et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The prognostic IDH1 R132 mutation is associated with reduced NADP+-dependent IDH activity in glioblastoma
- (2010) Fonnet E. Bleeker et al. ACTA NEUROPATHOLOGICA
- IDH1 Mutations Are Early Events in the Development of Astrocytomas and Oligodendrogliomas
- (2009) Takuya Watanabe et al. AMERICAN JOURNAL OF PATHOLOGY
- LIN54 is an essential core subunit of the DREAM/LINC complex that binds to the cdc2 promoter in a sequence-specific manner
- (2009) Fabienne Schmit et al. FEBS Journal
- Cancer-associated IDH1 mutations produce 2-hydroxyglutarate
- (2009) Lenny Dang et al. NATURE
- Recurring Mutations Found by Sequencing an Acute Myeloid Leukemia Genome
- (2009) Elaine R. Mardis et al. NEW ENGLAND JOURNAL OF MEDICINE
- IDH1andIDH2Mutations in Gliomas
- (2009) Hai Yan et al. NEW ENGLAND JOURNAL OF MEDICINE
- Thiazole Antibiotics Target FoxM1 and Induce Apoptosis in Human Cancer Cells
- (2009) Uppoor G. Bhat et al. PLoS One
- E3 ubiquitin ligase APC/C-Cdh1 accounts for the Warburg effect by linking glycolysis to cell proliferation
- (2009) A. Almeida et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- An Integrated Genomic Analysis of Human Glioblastoma Multiforme
- (2008) D. W. Parsons et al. SCIENCE
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started