Effects of age, BMI and sex on the glial cell marker TSPO — a multicentre [11C]PBR28 HRRT PET study

Characterization of the High-Affinity Drug Ligand Binding Site of Mouse Recombinant TSPO

(2019) Soria Iatmanen-Harbi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Building a database for brain 18 kDa translocator protein imaged using [11C]PBR28 in healthy subjects

(2018) Soumen Paul et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Influence of alcoholism and cholesterol on TSPO binding in brain: PET [11C]PBR28 studies in humans and rodents

(2018) Sung Won Kim et al.   NEUROPSYCHOPHARMACOLOGY

Sex-Specific Features of Microglia from Adult Mice

(2018) Alessandro Villa et al.   Cell Reports

Microglial Function across the Spectrum of Age and Gender

(2017) Jillian Nissen   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

11C-DPA-713 has much greater specific binding to translocator protein 18 kDa (TSPO) in human brain than 11C-(R)-PK11195

(2017) Masato Kobayashi et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Sifting through the surfeit of neuroinflammation tracers

(2017) Paul Cumming et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Reconceptualization of translocator protein as a biomarker of neuroinflammation in psychiatry

(2017) T Notter et al.   MOLECULAR PSYCHIATRY

Lower levels of the glial cell marker TSPO in drug-naive first-episode psychosis patients as measured using PET and [11C]PBR28

(2017) K Collste et al.   MOLECULAR PSYCHIATRY

Effect of Cigarette Smoking on a Marker for Neuroinflammation: A [11C]DAA1106 Positron Emission Tomography Study

(2017) Arthur L Brody et al.   NEUROPSYCHOPHARMACOLOGY

Assessment of simplified ratio-based approaches for quantification of PET [11C]PBR28 data

(2017) Granville J. Matheson et al.   EJNMMI Research

In vivo evidence of a functional association between immune cells in blood and brain in healthy human subjects

(2016) Naoki Kanegawa et al.   BRAIN BEHAVIOR AND IMMUNITY

Dietary obesity reversibly induces synaptic stripping by microglia and impairs hippocampal plasticity

(2016) Shuai Hao et al.   BRAIN BEHAVIOR AND IMMUNITY

Estrogens, Neuroinflammation, and Neurodegeneration

(2016) Alessandro Villa et al.   ENDOCRINE REVIEWS

Interactions between inflammation, sex steroids, and Alzheimer’s disease risk factors

(2016) Mariana F. Uchoa et al.   FRONTIERS IN NEUROENDOCRINOLOGY

Translocator protein (18kDa) as a pharmacological target in adipocytes to regulate glucose homeostasis

(2015) Jiehan Li et al.   BIOCHEMICAL PHARMACOLOGY

Effect of the myeloperoxidase inhibitor AZD3241 on microglia: a PET study in Parkinson’s disease

(2015) Aurelija Jucaite et al.   BRAIN

Roles of microglia in brain development, tissue maintenance and repair

(2015) Mackenzie A. Michell-Robinson et al.   BRAIN

Test–retest reproducibility of [11C]PBR28 binding to TSPO in healthy control subjects

(2015) K. Collste et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Structure and activity of tryptophan-rich TSPO proteins

(2015) Y. Guo et al.   SCIENCE

Evidence for a novel functional role of astrocytes in the acute homeostatic response to high-fat diet intake in mice

(2015) Laura B. Buckman et al.   Molecular Metabolism

High-fat diet consumption disrupts memory and primes elevations in hippocampal IL-1β, an effect that can be prevented with dietary reversal or IL-1 receptor antagonism

(2014) Julia L. Sobesky et al.   BRAIN BEHAVIOR AND IMMUNITY

Determination of [11C]PBR28 Binding Potential in vivo: A First Human TSPO Blocking Study

(2014) David R Owen et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Obesity Elicits Interleukin 1-Mediated Deficits in Hippocampal Synaptic Plasticity

(2014) J. R. Erion et al.   JOURNAL OF NEUROSCIENCE

The neuroinflammation marker translocator protein is not elevated in individuals with mild-to-moderate depression: A [11C]PBR28 PET study

(2013) Jonas Hannestad et al.   BRAIN BEHAVIOR AND IMMUNITY

Neuroinflammation in healthy aging: A PET study using a novel Translocator Protein 18kDa (TSPO) radioligand, [18F]-FEPPA

(2013) I. Suridjan et al.   NEUROIMAGE

Translocator Protein 18 kDa (TSPO) Is Regulated in White and Brown Adipose Tissue by Obesity

(2013) Misty M. Thompson et al.   PLoS One

An 18-kDa Translocator Protein (TSPO) Polymorphism Explains Differences in Binding Affinity of the PET Radioligand PBR28

(2011) David R Owen et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Age-related alterations in the dynamic behavior of microglia

(2010) Mausam R. Damani et al.   AGING CELL

Microglial activation in healthy aging

(2010) Alie Schuitemaker et al.   NEUROBIOLOGY OF AGING

Ex vivo cultures of microglia from young and aged rodent brain reveal age-related changes in microglial function

(2010) eMalick G. Njie et al.   NEUROBIOLOGY OF AGING

Translocator Protein 2 Is Involved in Cholesterol Redistribution during Erythropoiesis

(2009) Jinjiang Fan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Increased Binding of Peripheral Benzodiazepine Receptor in Alzheimer's Disease Measured by Positron Emission Tomography with [11C]DAA1106

(2008) Fumihiko Yasuno et al.   BIOLOGICAL PSYCHIATRY

Peripheral lipopolysaccharide (LPS) challenge promotes microglial hyperactivity in aged mice that is associated with exaggerated induction of both pro-inflammatory IL-1β and anti-inflammatory IL-10 cytokines

(2008) Christopher J. Henry et al.   BRAIN BEHAVIOR AND IMMUNITY

Expression of the translocator protein of 18 kDa by microglia, macrophages and astrocytes based on immunohistochemical localization in abnormal human brain

(2008) M. Cosenza-Nashat et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY