Microbial degradation of fluorinated drugs: biochemical pathways, impacts on the environment and potential applications

The biodegradation vs. biotransformation of fluorosubstituted aromatics

(2015) Martina Kiel et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Biotransformation of fluoroquinolone antibiotics by ligninolytic fungi – Metabolites, enzymes and residual antibacterial activity

(2015) Monika Čvančarová et al.   CHEMOSPHERE

Reviewing the serotonin reuptake inhibitors (SSRIs) footprint in the aquatic biota: Uptake, bioaccumulation and ecotoxicology

(2015) Liliana J.G. Silva et al.   ENVIRONMENTAL POLLUTION

Recent advances in fluorination techniques and their anticipated impact on drug metabolism and toxicity

(2015) Cormac D Murphy et al.   Expert Opinion on Drug Metabolism & Toxicology

Biotransformation of the Antibiotic Danofloxacin by Xylaria longipes Leads to an Efficient Reduction of Its Antibacterial Activity

(2015) Marina Rusch et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Production of drug metabolites by immobilised Cunninghamella elegans: from screening to scale up

(2015) Laura Quinn et al.   JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

Degradation of 5-FU by means of advanced (photo)oxidation processes: UV/H2O2, UV/Fe2+/H2O2 and UV/TiO2 — Comparison of transformation products, ready biodegradability and toxicity

(2015) Carlos Alexandre Lutterbeck et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Occurrence and removal of frequently prescribed pharmaceuticals and corresponding metabolites in wastewater of a sewage treatment plant

(2015) Robert Gurke et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Novel fluorinated lipopeptides from Bacillus sp. CS93 via precursor-directed biosynthesis

(2014) Neil K. O’Connor et al.   AMINO ACIDS

Degradation of benzotrifluoride via the dioxygenase pathway inRhodococcussp. 065240

(2014) Kenichi Yano et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Drug metabolism in microorganisms

(2014) Cormac D. Murphy   BIOTECHNOLOGY LETTERS

Enzymatic Fluorination and Biotechnological Developments of the Fluorinase

(2014) David O’Hagan et al.   CHEMICAL REVIEWS

Targeted Fluorination of a Nonsteroidal Anti-inflammatory Drug to Prolong Metabolic Half-Life

(2014) Maxwell J. Shaughnessy et al.   ChemMedChem

Enantioselective biodegradation of fluoxetine by the bacterial strain Labrys portucalensis F11

(2014) Irina S. Moreira et al.   CHEMOSPHERE

Biodegradation of ofloxacin, norfloxacin, and ciprofloxacin as single and mixed substrates by Labrys portucalensis F11

(2013) Catarina L. Amorim et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Microbial biotransformation of aryl sulfanylpentafluorides

(2013) Emma Kavanagh et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Fluorouracil in the environment: Analysis, occurrence, degradation and transformation

(2013) Tina Kosjek et al.   JOURNAL OF CHROMATOGRAPHY A

Fluorine Speciation Analysis Using Reverse Phase Liquid Chromatography Coupled Off-Line to Continuum Source Molecular Absorption Spectrometry (CS-MAS): Identification and Quantification of Novel Fluorinated Organic Compounds in Environmental and Biological Samples

(2012) Zhiwei Qin et al.   ANALYTICAL CHEMISTRY

Identification of the Enzyme Responsible for N -Acetylation of Norfloxacin by Microbacterium sp. Strain 4N2-2

(2012) Dae-Wi Kim et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Degradation of fluorobenzene and its central metabolites 3-fluorocatechol and 2-fluoromuconate by Burkholderia fungorum FLU100

(2012) Niko Strunk et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Bioaugmentation of Sewage Sludge with Trametes versicolor in Solid-Phase Biopiles Produces Degradation of Pharmaceuticals and Affects Microbial Communities

(2012) Carlos E. Rodríguez-Rodríguez et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Biocatalytic synthesis of flavones and hydroxyl-small molecules by recombinant Escherichia coli cells expressing the cyanobacterial CYP110E1 gene

(2012) Takuya Makino et al.   Microbial Cell Factories

Selective Continuous Flow Processes Using Fluorine Gas

(2012) Christopher B. McPake et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Metabolite proving fungal cleavage of the aromatic core part of a fluoroquinolone antibiotic

(2012) Heinz-Georg Wetzstein et al.   AMB Express

Modification of Norfloxacin by a Microbacterium sp. Strain Isolated from a Wastewater Treatment Plant

(2011) Dae-Wi Kim et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Isolation and characterization of a Rhodococcus strain able to degrade 2-fluorophenol

(2011) Anouk F. Duque et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Degradation of the antibiotics norfloxacin and ciprofloxacin by a white-rot fungus and identification of degradation products

(2011) Ailette Prieto et al.   BIORESOURCE TECHNOLOGY

Solid-phase treatment with the fungus Trametes versicolor substantially reduces pharmaceutical concentrations and toxicity from sewage sludge

(2011) Carlos E. Rodríguez-Rodríguez et al.   BIORESOURCE TECHNOLOGY

Bacterial production of hydroxylated and amidated metabolites of flurbiprofen

(2011) Tara V. Bright et al.   JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC

Production of anticancer polyenes through precursor-directed biosynthesis

(2011) Benjamin R. Clark et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Degradation of selected pharmaceutical and personal care products (PPCPs) by white-rot fungi

(2011) A. I. Rodarte-Morales et al.   WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY

Biotransformation of Flurbiprofen by Cunninghamella Species

(2010) J. Amadio et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Mineralization and transformation of monofluorophenols by Pseudonocardia benzenivorans

(2010) Eun-Ju Kim et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Biodegradation of polyfluorinated biphenyl in bacteria

(2010) David Hughes et al.   BIODEGRADATION

Production of human metabolites of the anti-cancer drug flutamide via biotransformation in Cunninghamella species

(2010) Jessica Amadio et al.   BIOTECHNOLOGY LETTERS

Microbial Metabolism. Part 11. Metabolites of Flutamide

(2010) Wimal Herath et al.   CHEMICAL & PHARMACEUTICAL BULLETIN

Synthesis of an 8-pentafluorosulfanyl analog of the antimalarial agent mefloquine

(2010) Tingting Mo et al.   TETRAHEDRON LETTERS

Biotransformation of fluorobiphenyl by Cunninghamella elegans

(2009) Jessica Amadio et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

An enzymatic route to 5-deoxy-5-[18F]fluoro-d-ribose, a [18F]-fluorinated sugar for PET imaging

(2009) Mayca Onega et al.   CHEMICAL COMMUNICATIONS

ENVIRONMENTAL PROPERTIES OF PENTAFLUOROSULFANYL COMPOUNDS: PHYSICAL PROPERTIES AND PHOTODEGRADATION

(2009) Derek A. Jackson et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Acetylation of fluoroquinolone antimicrobial agents by anEscherichia colistrain isolated from a municipal wastewater treatment plant

(2009) C.M. Jung et al.   JOURNAL OF APPLIED MICROBIOLOGY

Purification and properties of fluoroacetate dehalogenase from Pseudomonas fluorescens DSM 8341

(2008) Clár Donnelly et al.   BIOTECHNOLOGY LETTERS

Degradation of fluorobiphenyl byPseudomonas pseudoalcaligenesKF707

(2008) Cormac D. Murphy et al.   FEMS MICROBIOLOGY LETTERS

Perfluorinated compounds – Exposure assessment for the general population in western countries

(2008) Hermann Fromme et al.   INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH

Labrys portucalensis sp. nov., a fluorobenzene-degrading bacterium isolated from an industrially contaminated sediment in northern Portugal

(2008) M. F. Carvalho et al.   INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY

Chemo-enzymatic fluorination of unactivated organic compounds

(2008) Andrea Rentmeister et al.   Nature Chemical Biology