Natural products from filamentous fungi and production by heterologous expression

Identification and manipulation of the pleuromutilin gene cluster from Clitopilus passeckerianus for increased rapid antibiotic production

(2016) Andy M. Bailey et al.   Scientific Reports

Production of New Cladosporin Analogues by Reconstitution of the Polyketide Synthases Responsible for the Biosynthesis of this Antimalarial Agent

(2015) Rachel V. K. Cochrane et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Heterologous expression of a fungal sterol esterase/lipase in different hosts: Effect on solubility, glycosylation and production

(2015) María Eugenia Vaquero et al.   JOURNAL OF BIOSCIENCE AND BIOENGINEERING

Single-step fermentative production of the cholesterol-lowering drug pravastatin via reprogramming ofPenicillium chrysogenum

(2015) Kirsty J. McLean et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Heterologous expression of the avirulence gene ACE1 from the fungal rice pathogen Magnaporthe oryzae

(2015) Zhongshu Song et al.   Chemical Science

Rapid Reconstitution of Biosynthetic Machinery for Fungal Metabolites inAspergillus oryzae: Total Biosynthesis of Aflatrem

(2014) Koichi Tagami et al.   CHEMBIOCHEM

Antibiotic resistance needs global solutions

(2014) Alexander M Aiken et al.   LANCET INFECTIOUS DISEASES

Reconstructing fungal natural product biosynthetic pathways

(2014) C. M. Lazarus et al.   NATURAL PRODUCT REPORTS

NextGen microbial natural products discovery

(2014) Claudia Schmidt-Dannert   Microbial Biotechnology

Isolation and Characterisation of a Ferrirhodin Synthetase Gene from the Sugarcane PathogenFusarium sacchari

(2013) Asifa Munawar et al.   CHEMBIOCHEM

Total Synthesis of (+)-Pleuromutilin

(2013) Neal J. Fazakerley et al.   CHEMISTRY-A EUROPEAN JOURNAL

Gene clustering in plant specialized metabolism

(2013) Hans-Wilhelm Nützmann et al.   CURRENT OPINION IN BIOTECHNOLOGY

Recent advances in genome mining of secondary metabolite biosynthetic gene clusters and the development of heterologous expression systems in Aspergillus nidulans

(2013) Junko Yaegashi et al.   JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

Strategies for mining fungal natural products

(2013) Philipp Wiemann et al.   JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

Reconstitution of Biosynthetic Machinery for Indole-Diterpene Paxilline in Aspergillus oryzae

(2013) Koichi Tagami et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Heterologous Reconstitution of the Intact Geodin Gene Cluster in Aspergillus nidulans through a Simple and Versatile PCR Based Approach

(2013) Morten Thrane Nielsen et al.   PLoS One

Establishing a New Methodology for Genome Mining and Biosynthesis of Polyketides and Peptides through Yeast Molecular Genetics

(2012) Kan'ichiro Ishiuchi et al.   CHEMBIOCHEM

Genetic, molecular, and biochemical basis of fungal tropolone biosynthesis

(2012) J. Davison et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Total Biosynthesis of Diterpene Aphidicolin, a Specific Inhibitor of DNA Polymerase α: Heterologous Expression of Four Biosynthetic Genes inAspergillus oryzae

(2011) Ryuya FUJII et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Rational Domain Swaps Decipher Programming in Fungal Highly Reducing Polyketide Synthases and Resurrect an Extinct Metabolite

(2011) Katja M. Fisch et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

First Heterologous Reconstruction of a Complete Functional Fungal Biosynthetic Multigene Cluster

(2010) Mary N. Heneghan et al.   CHEMBIOCHEM

Fungal secondary metabolites – Strategies to activate silent gene clusters

(2010) Axel A. Brakhage et al.   FUNGAL GENETICS AND BIOLOGY

The antibiotics market

(2010) Bashar Hamad   NATURE REVIEWS DRUG DISCOVERY

Oral Fingolimod or Intramuscular Interferon for Relapsing Multiple Sclerosis

(2010) Jeffrey A. Cohen et al.   NEW ENGLAND JOURNAL OF MEDICINE

Secondary metabolic gene clusters: evolutionary toolkits for chemical innovation

(2010) Anne Osbourn   TRENDS IN GENETICS

Establishing Molecular Tools for Genetic Manipulation of the Pleuromutilin-Producing Fungus Clitopilus passeckerianus

(2009) S. Kilaru et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Investigating pleuromutilin-producingClitopilusspecies and related basidiomycetes

(2009) Amanda J. Hartley et al.   FEMS MICROBIOLOGY LETTERS

Complete Reconstitution of a Highly Reducing Iterative Polyketide Synthase

(2009) S. M. Ma et al.   SCIENCE

Construction of a Citrinin Gene Cluster Expression System in Heterologous Aspergillus oryzae

(2008) Kanae Sakai et al.   JOURNAL OF BIOSCIENCE AND BIOENGINEERING