Identification and manipulation of the pleuromutilin gene cluster from Clitopilus passeckerianus for increased rapid antibiotic production

Synthesis of novel pleuromutilin derivatives. Part 1: Preliminary studies of antituberculosis activity

(2015) Ying-Jie Dong et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Design, Synthesis, and Structure–Activity Relationship Studies of Novel Thioether Pleuromutilin Derivatives as Potent Antibacterial Agents

(2014) Chenyu Ling et al.   JOURNAL OF MEDICINAL CHEMISTRY

Total Synthesis of (+)-Pleuromutilin

(2013) Neal J. Fazakerley et al.   CHEMISTRY-A EUROPEAN JOURNAL

Transgene Induced Co-Suppression during Vegetative Growth in Cryptococcus neoformans

(2012) Xuying Wang et al.   PLoS Genetics

Total Biosynthesis of Diterpene Aphidicolin, a Specific Inhibitor of DNA Polymerase α: Heterologous Expression of Four Biosynthetic Genes inAspergillus oryzae

(2011) Ryuya FUJII et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

First Heterologous Reconstruction of a Complete Functional Fungal Biosynthetic Multigene Cluster

(2010) Mary N. Heneghan et al.   CHEMBIOCHEM

Establishing Molecular Tools for Genetic Manipulation of the Pleuromutilin-Producing Fungus Clitopilus passeckerianus

(2009) S. Kilaru et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Investigating pleuromutilin-producingClitopilusspecies and related basidiomycetes

(2009) Amanda J. Hartley et al.   FEMS MICROBIOLOGY LETTERS

Biosynthetic Gene-Based Secondary Metabolite Screening: A New Diterpene, Methyl Phomopsenonate, from the FungusPhomopsis amygdali

(2009) Tomonobu Toyomasu et al.   JOURNAL OF ORGANIC CHEMISTRY

Late Stage Oxidations during the Biosynthesis of the 2-Pyridone Tenellin in the Entomopathogenic FungusBeauveria bassiana

(2008) Laura M. Halo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Natural products to drugs: natural product-derived compounds in clinical trials

(2008) Mark S. Butler   NATURAL PRODUCT REPORTS

The pleuromutilin drugs tiamulin and valnemulin bind to the RNA at the peptidyl transferase centre on the ribosome

(2003) Susan M. Poulsen et al.   MOLECULAR MICROBIOLOGY