Adaptive Immunity in Hypertension

1,2,3,4,6 penta-O -galloyl-β-D-glucose modulates perivascular inflammation and prevents vascular dysfunction in angiotensin II-induced hypertension.

(2019) Tomasz P. Mikolajczyk et al.   BRITISH JOURNAL OF PHARMACOLOGY

B-Cell Deficiency Lowers Blood Pressure in Mice

(2019) Luke S. Dingwell et al.   HYPERTENSION

PD-1/PD-L1 regulates Treg differentiation in pregnancy-induced hypertension

(2018) Lai Jiang et al.   BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH

Hypertension and increased endothelial mechanical stretch promote monocyte differentiation and activation: roles of STAT3, interleukin 6 and hydrogen peroxide

(2018) Roxana Loperena et al.   CARDIOVASCULAR RESEARCH

Dynamic and diverse changes in the functional properties of vascular smooth muscle cells in pulmonary hypertension

(2018) Kurt R Stenmark et al.   CARDIOVASCULAR RESEARCH

Multiple common comorbidities produce left ventricular diastolic dysfunction associated with coronary microvascular dysfunction, oxidative stress, and myocardial stiffening

(2018) Oana Sorop et al.   CARDIOVASCULAR RESEARCH

Deoxycorticosterone acetate-salt hypertension activates placental growth factor in the spleen to couple sympathetic drive and immune system activation

(2018) Marialuisa Perrotta et al.   CARDIOVASCULAR RESEARCH

Brain MRI fiber-tracking reveals white matter alterations in hypertensive patients without damage at conventional neuroimaging

(2018) Lorenzo Carnevale et al.   CARDIOVASCULAR RESEARCH

Vascular smooth muscle contraction in hypertension

(2018) Rhian M Touyz et al.   CARDIOVASCULAR RESEARCH

OUP accepted manuscript

(2018)   CARDIOVASCULAR RESEARCH

Myeloid CD11c+Antigen-Presenting Cells Ablation Prevents Hypertension in Response to Angiotensin II Plus High-Salt DietNovelty and Significance

(2018) Daniel Hevia et al.   HYPERTENSION

Nox2 in regulatory T cells promotes angiotensin II–induced cardiovascular remodeling

(2018) Amber Emmerson et al.   JOURNAL OF CLINICAL INVESTIGATION

Sex bias in MHC I-associated shaping of the adaptive immune system

(2018) Tilman Schneider-Hohendorf et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Angiotensin II-induced Hypertension is Reduced by Deficiency of P-selectin Glycoprotein Ligand-1

(2018) Qian Wang et al.   Scientific Reports

Interleukin-12p35 knockout promotes macrophage differentiation, aggravates vascular dysfunction, and elevates blood pressure in angiotensin II-infused mice

(2018) Jing Ye et al.   CARDIOVASCULAR RESEARCH

In renovascular hypertension, TNF-α type-1 receptors in the area postrema mediate increases in cardiac and renal sympathetic nerve activity and blood pressure

(2018) Willian S Korim et al.   CARDIOVASCULAR RESEARCH

SGK1-FoxO1 Signaling Pathway Mediates Th17/Treg Imbalance and Target Organ Inflammation in Angiotensin II-Induced Hypertension

(2018) Ya-Nan Du et al.   Frontiers in Physiology

Treg cells depletion is a mechanism that drives microvascular dysfunction in mice with established hypertension

(2018) Eman Radwan et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

The immunology of hypertension

(2017) Allison E. Norlander et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Interleukin 17A and Toll-like Receptor 4 in Patients with Arterial Hypertension

(2017) Tihana Simundic et al.   KIDNEY & BLOOD PRESSURE RESEARCH

Dysfunction of the thymus in mice with hypertension

(2017) Xianliang Dai et al.   Experimental and Therapeutic Medicine

Rapid Recall Ability of Memory T cells is Encoded in their Epigenome

(2017) Artem Barski et al.   Scientific Reports

A Single Angiotensin II Hypertensive Stimulus Is Associated with Prolonged Neuronal and Immune System Activation in Wistar-Kyoto Rats

(2017) Jasenka Zubcevic et al.   Frontiers in Physiology

Vascular transcriptome profiling identifies Sphingosine kinase 1 as a modulator of angiotensin II-induced vascular dysfunction

(2017) Mateusz Siedlinski et al.   Scientific Reports

CD70 Exacerbates Blood Pressure Elevation and Renal Damage in Response to Repeated Hypertensive StimuliNovelty and Significance

(2016) Hana A. Itani et al.   CIRCULATION RESEARCH

Role of chemokine RANTES in the regulation of perivascular inflammation, T-cell accumulation, and vascular dysfunction in hypertension

(2016) Tomasz P. Mikolajczyk et al.   FASEB JOURNAL

Activation of Human T Cells in HypertensionNovelty and Significance

(2016) Hana A. Itani et al.   HYPERTENSION

Interleukin-17A Regulates Renal Sodium Transporters and Renal Injury in Angiotensin II–Induced HypertensionNovelty and Significance

(2016) Allison E. Norlander et al.   HYPERTENSION

Interleukin-10 limits increased blood pressure and vascular RhoA/Rho-kinase signaling in angiotensin II-infused mice

(2016) Victor V. Lima et al.   LIFE SCIENCES

Renal Tumor Necrosis Factor α Contributes to Hypertension in Dahl Salt-Sensitive Rats

(2016) Baorui Huang et al.   Scientific Reports

Inflammasome activity is essential for one kidney/deoxycorticosterone acetate/salt-induced hypertension in mice

(2015) S M Krishnan et al.   BRITISH JOURNAL OF PHARMACOLOGY

Sex-specific immune modulation of primary hypertension

(2015) Kathryn Sandberg et al.   CELLULAR IMMUNOLOGY

Myeloid Suppressor Cells Accumulate and Regulate Blood Pressure in HypertensionNovelty and Significance

(2015) Kandarp H. Shah et al.   CIRCULATION RESEARCH

Renal Transporter Activation During Angiotensin-II Hypertension is Blunted in Interferon-γ−/−and Interleukin-17A−/−MiceNovelty and Significance

(2015) Nikhil V. Kamat et al.   HYPERTENSION

Obligatory Role for B Cells in the Development of Angiotensin II–Dependent HypertensionNovelty and Significance

(2015) Christopher T. Chan et al.   HYPERTENSION

CCL5 upregulates IL-10 expression and partially mediates the antihypertensive effects of IL-10 in the vascular smooth muscle cells of spontaneously hypertensive rats

(2015) Hye Young Kim et al.   HYPERTENSION RESEARCH

Elevated Serum Level of Interleukin 17 in a Population With Prehypertension

(2015) Wei Yao et al.   Journal of Clinical Hypertension

Lymphocyte adaptor protein LNK deficiency exacerbates hypertension and end-organ inflammation

(2015) Mohamed A. Saleh et al.   JOURNAL OF CLINICAL INVESTIGATION

Heterogeneity of peripheral blood monocytes, endothelial dysfunction and subclinical atherosclerosis in patients with systemic lupus erythematosus

(2015) T P Mikołajczyk et al.   LUPUS

Hypertensive Renal Injury Is Associated With Gene Variation Affecting Immune Signaling

(2014) M. C. Braun et al.   Circulation-Cardiovascular Genetics

Sex Differences in T Cells in Hypertension

(2014) Ashlee J. Tipton et al.   CLINICAL THERAPEUTICS

Diversity in the preimmune immunoglobulin repertoire of SHR lines susceptible and resistant to end-organ injury

(2014) M L Gonzalez-Garay et al.   GENES AND IMMUNITY

Female Spontaneously Hypertensive Rats Have a Compensatory Increase in Renal Regulatory T Cells in Response to Elevations in Blood Pressure

(2014) Ashlee J. Tipton et al.   HYPERTENSION

Oligoclonal CD8 + T Cells Play a Critical Role in the Development of Hypertension

(2014) Daniel W. Trott et al.   HYPERTENSION

Sex-Specific T-Cell Regulation of Angiotensin II–Dependent Hypertension

(2014) Hong Ji et al.   HYPERTENSION

Sex Differences in T-Lymphocyte Tissue Infiltration and Development of Angiotensin II Hypertension

(2014) Dennis P. Pollow et al.   HYPERTENSION

Spironolactone Decreases DOCA–Salt–Induced Organ Damage by Blocking the Activation of T Helper 17 and the Downregulation of Regulatory T Lymphocytes

(2014) Cristián A. Amador et al.   HYPERTENSION

Tumor Necrosis Factor-α Produced in the Kidney Contributes to Angiotensin II–dependent Hypertension

(2014) Jiandong Zhang et al.   HYPERTENSION

The Angiogenic Factor PlGF Mediates a Neuroimmune Interaction in the Spleen to Allow the Onset of Hypertension

(2014) Daniela Carnevale et al.   IMMUNITY

DC isoketal-modified proteins activate T cells and promote hypertension

(2014) Annet Kirabo et al.   JOURNAL OF CLINICAL INVESTIGATION

Rheumatoid arthritis and cardiovascular disease

(2013) Cynthia S. Crowson et al.   AMERICAN HEART JOURNAL

Immunosenescent CD8 + T Cells and C-X-C Chemokine Receptor Type 3 Chemokines Are Increased in Human Hypertension

(2013) Jong-Chan Youn et al.   HYPERTENSION

Senescent T Cells and Hypertension

(2013) Meena S. Madhur et al.   HYPERTENSION

Administration of Interleukin-17 Soluble Receptor C Suppresses T H 17 Cells, Oxidative Stress, and Hypertension in Response to Placental Ischemia During Pregnancy

(2013) Denise C. Cornelius et al.   HYPERTENSION

A leading role for the immune system in the pathophysiology of preeclampsia

(2013) Estibalitz Laresgoiti-Servitje   JOURNAL OF LEUKOCYTE BIOLOGY

Induction of pathogenic TH17 cells by inducible salt-sensing kinase SGK1

(2013) Chuan Wu et al.   NATURE

Sodium chloride drives autoimmune disease by the induction of pathogenic TH17 cells

(2013) Markus Kleinewietfeld et al.   NATURE

Interleukin-17 causes Rho-kinase-mediated endothelial dysfunction and hypertension

(2012) Hoanglan Nguyen et al.   CARDIOVASCULAR RESEARCH

Interferon-γ Signaling Inhibition Ameliorates Angiotensin II–Induced Cardiac Damage

(2012) Lajos Markó et al.   HYPERTENSION

Female Mice are Protected against High-Fat Diet Induced Metabolic Syndrome and Increase the Regulatory T Cell Population in Adipose Tissue

(2012) Ulrika S. Pettersson et al.   PLoS One

Natural Regulatory T Cells Control Coronary Arteriolar Endothelial Dysfunction in Hypertensive Mice

(2011) Khalid Matrougui et al.   AMERICAN JOURNAL OF PATHOLOGY

Interleukin-10 Released by CD4 + CD25 + Natural Regulatory T Cells Improves Microvascular Endothelial Function Through Inhibition of NADPH Oxidase Activity in Hypertensive Mice

(2011) Modar Kassan et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

High-Resolution Identity by Descent Mapping Uncovers the Genetic Basis for Blood Pressure Differences Between Spontaneously Hypertensive Rat Lines

(2011) Rebecca Bell et al.   Circulation-Cardiovascular Genetics

Correlation Between HLA-DRB1, HLA-DQB1 Polymorphism and Autoantibodies Against Angiotensin AT1 Receptors in Chinese Patients With Essential Hypertension

(2011) Feng Zhu et al.   CLINICAL CARDIOLOGY

T Regulatory Lymphocytes Prevent Angiotensin II–Induced Hypertension and Vascular Injury

(2011) Tlili Barhoumi et al.   HYPERTENSION

Immune regulation and vascular inflammation in genetic hypertension

(2010) Emilie C. Viel et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

T Cells and Blood Vessels

(2010) De-xiu Bu et al.   CIRCULATION

Inhibition and Genetic Ablation of the B7/CD28 T-Cell Costimulation Axis Prevents Experimental Hypertension

(2010) Antony Vinh et al.   CIRCULATION

Central and Peripheral Mechanisms of T-Lymphocyte Activation and Vascular Inflammation Produced by Angiotensin II–Induced Hypertension

(2010) Paul J. Marvar et al.   CIRCULATION RESEARCH

High Dietary Protein Exacerbates Hypertension and Renal Damage in Dahl SS Rats by Increasing Infiltrating Immune Cells in the Kidney

(2010) Carmen De Miguel et al.   HYPERTENSION

Protective actions of estrogen on angiotensin II-induced hypertension: role of central nitric oxide

(2009) Baojian Xue et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Regulatory T Cells Ameliorate Angiotensin II–Induced Cardiac Damage

(2009) Heda Kvakan et al.   CIRCULATION

Endogenous Interleukin-10 Inhibits Angiotensin II–Induced Vascular Dysfunction

(2009) Sean P. Didion et al.   HYPERTENSION

Interleukin 17 Promotes Angiotensin II–Induced Hypertension and Vascular Dysfunction

(2009) Meena S. Madhur et al.   HYPERTENSION

Angiotensin Receptor Agonistic Autoantibody Is Highly Prevalent in Preeclampsia

(2009) Athar H. Siddiqui et al.   HYPERTENSION

Central estrogen inhibition of angiotensin II-induced hypertension in male mice and the role of reactive oxygen species

(2008) Baojian Xue et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Joint Effects of Antibody to Heat Shock Protein 60, Hypertension, and Diabetes on Risk of Coronary Heart Disease in Chinese

(2008) X. Zhang et al.   CLINICAL CHEMISTRY

Involvement of Tumor Necrosis Factor-α in Angiotensin II–Mediated Effects on Salt Appetite, Hypertension, and Cardiac Hypertrophy

(2008) Srinivas Sriramula et al.   HYPERTENSION

Potential Relevance of α1-Adrenergic Receptor Autoantibodies in Refractory Hypertension

(2008) Katrin Wenzel et al.   PLoS One