Genomewide Association Study of Statin‐Induced Myopathy in Patients Recruited Using the UK Clinical Practice Research Datalink

Association between SLCO1B1 T521C polymorphism and risk of statin-induced myopathy: a meta-analysis

(2018) Qian Xiang et al.   PHARMACOGENOMICS JOURNAL

Interpretation of the evidence for the efficacy and safety of statin therapy

(2016) Rory Collins et al.   LANCET

Dense genotyping of immune-related loci in idiopathic inflammatory myopathies confirms HLA alleles as the strongest genetic risk factor and suggests different genetic background for major clinical subgroups

(2015) Simon Rothwell et al.   ANNALS OF THE RHEUMATIC DISEASES

SLCO1B1 polymorphism markedly affects the pharmacokinetics of lovastatin acid

(2015) Aleksi Tornio et al.   Pharmacogenetics and Genomics

Predictors and outcomes of increases in creatine phosphokinase concentrations or rhabdomyolysis risk during statin treatment

(2014) Tjeerd P. van Staa et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Phenotype Standardization for Statin-Induced Myotoxicity

(2014) A Alfirevic et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

GATM gene variants and statin myopathy risk

(2014) D. F. Carr et al.   NATURE

GATM locus does not replicate in rhabdomyolysis study

(2014) James S. Floyd et al.   NATURE

Electronic health records for biological sample collection: feasibility study of statin-induced myopathy using the Clinical Practice Research Datalink

(2013) Helen O'Meara et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

SLCO1B1 Genetic Variant Associated With Statin-Induced Myopathy: A Proof-of-Concept Study Using the Clinical Practice Research Datalink

(2013) D F Carr et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

A statin-dependent QTL for GATM expression is associated with statin-induced myopathy

(2013) Lara M. Mangravite et al.   NATURE

A high-performance computing toolset for relatedness and principal component analysis of SNP data

(2012) X. Zheng et al.   BIOINFORMATICS

Impact of common genetic variation on response to simvastatin therapy among 18 705 participants in the Heart Protection Study

(2012) Jemma C. Hopewell et al.   EUROPEAN HEART JOURNAL

Fast and accurate genotype imputation in genome-wide association studies through pre-phasing

(2012) Bryan Howie et al.   NATURE GENETICS

Genetic Influence in Statin Intolerance

(2011) L Puccetti et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Association of common variants in the human eyes shut ortholog (EYS) with statin-induced myopathy: Evidence for additional functions of EYS

(2011) Paul J. Isackson et al.   MUSCLE & NERVE

A linear complexity phasing method for thousands of genomes

(2011) Olivier Delaneau et al.   NATURE METHODS

Cerivastatin, genetic variants, and the risk of rhabdomyolysis

(2011) Kristin D. Marciante et al.   Pharmacogenetics and Genomics

Differential effect of the rs4149056 variant in SLCO1B1 on myopathy associated with simvastatin and atorvastatin

(2011) L R Brunham et al.   PHARMACOGENOMICS JOURNAL

Genotype Imputation with Thousands of Genomes

(2011) Bryan Howie et al.   G3-Genes Genomes Genetics

GWAMA: software for genome-wide association meta-analysis

(2010) Reedik Mägi et al.   BMC BIOINFORMATICS

Common Nonsynonymous Substitutions in SLCO1B1 Predispose to Statin Intolerance in Routinely Treated Individuals With Type 2 Diabetes: A Go-DARTS Study

(2010) L A Donnelly et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Intestinal Absorption of HMG-CoA Reductase Inhibitor Pitavastatin Mediated by Organic Anion Transporting Polypeptide and P-Glycoprotein/Multidrug Resistance 1

(2010) Yoshiyuki Shirasaka et al.   Drug Metabolism and Pharmacokinetics

Impact of OATP transporters on pharmacokinetics

(2009) A Kalliokoski et al.   BRITISH JOURNAL OF PHARMACOLOGY

Transporter Pharmacogenetics and Statin Toxicity

(2009) M Niemi   CLINICAL PHARMACOLOGY & THERAPEUTICS

The SLCO1B1*5Genetic Variant Is Associated With Statin-Induced Side Effects

(2009) Deepak Voora et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Pharmacogenetics of the organic anion transporting polypeptide 1A2

(2009) Ryan M Franke et al.   PHARMACOGENOMICS

A Flexible and Accurate Genotype Imputation Method for the Next Generation of Genome-Wide Association Studies

(2009) Bryan N. Howie et al.   PLoS Genetics

SLCO1B1Variants and Statin-Induced Myopathy — A Genomewide Study

(2008)   NEW ENGLAND JOURNAL OF MEDICINE

The effect of SLCO1B1*15 on the disposition of pravastatin and pitavastatin is substrate dependent: the contribution of transporting activity changes by SLCO1B1*15

(2008) Jian Wei Deng et al.   Pharmacogenetics and Genomics