Structural Investigations on the Interactions between Cytidine Deaminase Human APOBEC3G and DNA

Perspective: APOBEC mutagenesis in drug resistance and immune escape in HIV and cancer evolution

(2018) S Venkatesan et al.   ANNALS OF ONCOLOGY

Molecular Interactions of a DNA Modifying Enzyme APOBEC3F Catalytic Domain with a Single-Stranded DNA

(2018) Yao Fang et al.   JOURNAL OF MOLECULAR BIOLOGY

Modeling the Embrace of a Mutator: APOBEC Selection of Nucleic Acid Ligands

(2018) Jason D. Salter et al.   TRENDS IN BIOCHEMICAL SCIENCES

Crystal structure of the catalytic domain of HIV-1 restriction factor APOBEC3G in complex with ssDNA

(2018) Atanu Maiti et al.   Nature Communications

Crystal Structure of Cytidine Deaminase Human APOBEC3F Chimeric Catalytic Domain in Complex with DNA

(2018) Chao Cheng et al.   CHINESE JOURNAL OF CHEMISTRY

Crystal structure of APOBEC3A bound to single-stranded DNA reveals structural basis for cytidine deamination and specificity

(2017) Takahide Kouno et al.   Nature Communications

A Novel Regulator of Activation-Induced Cytidine Deaminase/APOBECs in Immunity and Cancer: Schrödinger’s CATalytic Pocket

(2017) Justin J. King et al.   Frontiers in Immunology

Apobec3G-Based Strategies to Defeat HIV Infection

(2016) Xiaozhuo Ran et al.   CURRENT HIV RESEARCH

Structural and functional assessment of APOBEC3G macromolecular complexes

(2016) Bogdan Polevoda et al.   METHODS

Structural basis for targeted DNA cytosine deamination and mutagenesis by APOBEC3A and APOBEC3B

(2016) Ke Shi et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Crystal structures of APOBEC3G N-domain alone and its complex with DNA

(2016) Xiao Xiao et al.   Nature Communications

Structural basis for targeted DNA cytosine deamination and mutagenesis by APOBEC3A and APOBEC3B

(2016) Ke Shi et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Catalytic Analysis of APOBEC3G Involving Real-Time NMR Spectroscopy Reveals Nucleic Acid Determinants for Deamination

(2015) Keisuke Kamba et al.   PLoS One

Crystal Structure of DNA Cytidine Deaminase ABOBEC3G Catalytic Deamination Domain Suggests a Binding Mode of Full-length Enzyme to Single-stranded DNA

(2014) Xiuxiu Lu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The multifaceted roles of RNA binding in APOBEC cytidine deaminase functions

(2014) Kimberly M. Prohaska et al.   Wiley Interdisciplinary Reviews-RNA

Efficient Deamination of 5-Methylcytidine and 5-Substituted Cytidine Residues in DNA by Human APOBEC3A Cytidine Deaminase

(2013) Rodolphe Suspène et al.   PLoS One

AID/APOBEC cytosine deaminase induces genome-wide kataegis

(2012) Artem G Lada et al.   Biology Direct

First-In-Class Small Molecule Inhibitors of the Single-Strand DNA Cytosine Deaminase APOBEC3G

(2011) Ming Li et al.   ACS Chemical Biology

T-cell differentiation factor CBF-β regulates HIV-1 Vif-mediated evasion of host restriction

(2011) Wenyan Zhang et al.   NATURE

Vif hijacks CBF-β to degrade APOBEC3G and promote HIV-1 infection

(2011) Stefanie Jäger et al.   NATURE

Structural Model for Deoxycytidine Deamination Mechanisms of the HIV-1 Inactivation Enzyme APOBEC3G

(2010) Linda Chelico et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crystal Structure of the APOBEC3G Catalytic Domain Reveals Potential Oligomerization Interfaces

(2010) Shivender M.D. Shandilya et al.   STRUCTURE

Structure, interaction and real-time monitoring of the enzymatic reaction of wild-type APOBEC3G

(2009) Ayako Furukawa et al.   EMBO JOURNAL

Dissecting APOBEC3G Substrate Specificity by Nucleoside Analog Interference

(2009) Jason W. Rausch et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

An Extended Structure of the APOBEC3G Catalytic Domain Suggests a Unique Holoenzyme Model

(2009) Elena Harjes et al.   JOURNAL OF MOLECULAR BIOLOGY

A Model for Oligomeric Regulation of APOBEC3G Cytosine Deaminase-dependent Restriction of HIV

(2008) Linda Chelico et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Guidelines for Naming Nonprimate APOBEC3 Genes and Proteins

(2008) R. S. LaRue et al.   JOURNAL OF VIROLOGY

Crystal structure of the anti-viral APOBEC3G catalytic domain and functional implications

(2008) Lauren G. Holden et al.   NATURE

Structure of the DNA deaminase domain of the HIV-1 restriction factor APOBEC3G

(2008) Kuan-Ming Chen et al.   NATURE

HIV-1 Vif, APOBEC, and Intrinsic Immunity

(2008) Ritu Goila-Gaur et al.   Retrovirology