ATAT1 regulates forebrain development and stress-induced tubulin hyperacetylation

TAK1 activation of alpha-TAT1 and microtubule hyperacetylation control AKT signaling and cell growth

(2018) Nirav Shah et al.   Nature Communications

Salt-responsive gut commensal modulates TH17 axis and disease

(2017) Nicola Wilck et al.   NATURE

Tubulin acetylation protects long-lived microtubules against mechanical ageing

(2017) Didier Portran et al.   NATURE CELL BIOLOGY

Microtubules acquire resistance from mechanical breakage through intralumenal acetylation

(2017) Zhenjie Xu et al.   SCIENCE

Critical role of the HDAC6–cortactin axis in human megakaryocyte maturation leading to a proplatelet-formation defect

(2017) Kahia Messaoudi et al.   Nature Communications

Cholesterol in platelet biogenesis and activation

(2016) N. Wang et al.   BLOOD

BRPF1 is essential for development of fetal hematopoietic stem cells

(2016) Linya You et al.   JOURNAL OF CLINICAL INVESTIGATION

Acetylated tubulin is essential for touch sensation in mice

(2016) Shane J Morley et al.   eLife

HDAC6 inhibition induces mitochondrial fusion, autophagic flux and reduces diffuse mutant huntingtin in striatal neurons

(2015) Pedro Guedes-Dias et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Platelet disorders

(2015) Manasa Krishnegowda et al.   BLOOD COAGULATION & FIBRINOLYSIS

Tubulin acetylation: responsible enzymes, biological functions and human diseases

(2015) Lin Li et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

GeneMatcher: A Matching Tool for Connecting Investigators with an Interest in the Same Gene

(2015) Nara Sobreira et al.   HUMAN MUTATION

The Chromatin Regulator BRPF3 Preferentially Activates the HBO1 Acetyltransferase but Is Dispensable for Mouse Development and Survival

(2015) Kezhi Yan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Deficiency of the Chromatin Regulator Brpf1 Causes Abnormal Brain Development

(2015) Linya You et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Selective reduction of striatal mature BDNF without induction of proBDNF in the zQ175 mouse model of Huntington's disease

(2015) Qian Ma et al.   NEUROBIOLOGY OF DISEASE

The Lysine Acetyltransferase Activator Brpf1 Governs Dentate Gyrus Development through Neural Stem Cells and Progenitors

(2015) Linya You et al.   PLoS Genetics

 -Tubulin Acetylation Elevated in Metastatic and Basal-like Breast Cancer Cells Promotes Microtentacle Formation, Adhesion, and Invasive Migration

(2014) A. E. Boggs et al.   CANCER RESEARCH

Microtubule acetylation amplifies p38 kinase signalling and anti-inflammatory IL-10 production

(2014) Bin Wang et al.   Nature Communications

The emerging role of acetylation in the regulation of autophagy

(2013) Ágnes Bánréti et al.   Autophagy

Acetylation of α-Tubulin on Lys40Is a Widespread Post-Translational Modification in Angiosperms

(2013) Umihito NAKAGAWA et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Mice Lacking α-Tubulin Acetyltransferase 1 Are Viable but Display α-Tubulin Acetylation Deficiency and Dentate Gyrus Distortion

(2013) Go-Woon Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Tumor Suppressor Kinase LKB1 Activates the Downstream Kinases SIK2 and SIK3 to Stimulate Nuclear Export of Class IIa Histone Deacetylases

(2013) Donald R. Walkinshaw et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Effects of tubulin acetylation and tubulin acetyltransferase binding on microtubule structure

(2013) Stuart C. Howes et al.   MOLECULAR BIOLOGY OF THE CELL

HDAC6 as a target for neurodegenerative diseases: what makes it different from the other HDACs?

(2013) Claudia Simões-Pires et al.   Molecular Neurodegeneration

Genetic deletion of Rnd3 results in aqueductal stenosis leading to hydrocephalus through up-regulation of Notch signaling

(2013) X. Lin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

αTAT1 is the major α-tubulin acetyltransferase in mice

(2013) Nereo Kalebic et al.   Nature Communications

HDAC6 controls the kinetics of platelet activation

(2012) K. Sadoul et al.   BLOOD

Posttranslational Acetylation of α-Tubulin Constrains Protofilament Number in Native Microtubules

(2012) Juan G. Cueva et al.   CURRENT BIOLOGY

Genetically Separable Functions of the MEC-17 Tubulin Acetyltransferase Affect Microtubule Organization

(2012) Irini Topalidou et al.   CURRENT BIOLOGY

Heat shock induces rapid resorption of primary cilia

(2012) N. V. Prodromou et al.   JOURNAL OF CELL SCIENCE

MEC-17 Deficiency Leads to Reduced  -Tubulin Acetylation and Impaired Migration of Cortical Neurons

(2012) L. Li et al.   JOURNAL OF NEUROSCIENCE

Hdac6 Knock-Out Increases Tubulin Acetylation but Does Not Modify Disease Progression in the R6/2 Mouse Model of Huntington's Disease

(2011) Anna Bobrowska et al.   PLoS One

Cut homeobox 1 causes chromosomal instability by promoting bipolar division after cytokinesis failure

(2011) Laurent Sansregret et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Acetylated microtubules are required for fusion of autophagosomes with lysosomes

(2010) Rui Xie et al.   BMC CELL BIOLOGY

Myc-Nick: A Cytoplasmic Cleavage Product of Myc that Promotes α-Tubulin Acetylation and Cell Differentiation

(2010) Maralice Conacci-Sorrell et al.   CELL

Starvation-induced Hyperacetylation of Tubulin Is Required for the Stimulation of Autophagy by Nutrient Deprivation

(2010) Camille Geeraert et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MEC-17 is an α-tubulin acetyltransferase

(2010) Jyothi S. Akella et al.   NATURE

The major  -tubulin K40 acetyltransferase  TAT1 promotes rapid ciliogenesis and efficient mechanosensation

(2010) T. Shida et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Elongator Controls the Migration and Differentiation of Cortical Neurons through Acetylation of α-Tubulin

(2009) Catherine Creppe et al.   CELL

Traveling waves in developing cerebellar cortex mediated by asymmetrical Purkinje cell connectivity

(2009) Alanna J Watt et al.   NATURE NEUROSCIENCE

Mice Lacking Histone Deacetylase 6 Have Hyperacetylated Tubulin but Are Viable and Develop Normally

(2008) Y. Zhang et al.   MOLECULAR AND CELLULAR BIOLOGY

Striatal Plasticity and Basal Ganglia Circuit Function

(2008) Anatol C. Kreitzer et al.   NEURON