Alzheimer’s pathology targets distinct memory networks in the ageing brain

Functional connectivity associated with tau levels in ageing, Alzheimer’s, and small vessel disease

(2019) Nicolai Franzmeier et al.   BRAIN

Tau seeding activity begins in the transentorhinal/entorhinal regions and anticipates phospho-tau pathology in Alzheimer’s disease and PART

(2018) Sarah K. Kaufman et al.   ACTA NEUROPATHOLOGICA

NIA-AA Research Framework: Toward a biological definition of Alzheimer's disease

(2018) Clifford R. Jack et al.   Alzheimers & Dementia

Tau burden and the functional connectome in Alzheimer’s disease and progressive supranuclear palsy

(2018) Thomas E Cope et al.   BRAIN

Early Tau Burden Correlates with Higher Rate of Atrophy in Transentorhinal Cortex

(2018) Long Xie et al.   JOURNAL OF ALZHEIMERS DISEASE

Subthreshold Amyloid Predicts Tau Deposition in Aging

(2018) Stephanie L. Leal et al.   JOURNAL OF NEUROSCIENCE

Structural tract alterations predict downstream tau accumulation in amyloid-positive older individuals

(2018) Heidi I. L. Jacobs et al.   NATURE NEUROSCIENCE

Integrating new findings and examining clinical applications of pattern separation

(2018) Stephanie L. Leal et al.   NATURE NEUROSCIENCE

Age-related functional changes in domain-specific medial temporal lobe pathways

(2018) David Berron et al.   NEUROBIOLOGY OF AGING

Both hyper- and hypo-activation to cognitive challenge are associated with increased beta-amyloid deposition in healthy aging: A nonlinear effect

(2018) Chris M. Foster et al.   NEUROIMAGE

Functional Imbalance of Anterolateral Entorhinal Cortex and Hippocampal Dentate/CA3 Underlies Age-Related Object Pattern Separation Deficits

(2018) Zachariah M. Reagh et al.   NEURON

Shared Functions of Perirhinal and Parahippocampal Cortices: Implications for Cognitive Aging

(2018) Sara N. Burke et al.   TRENDS IN NEUROSCIENCES

On the origin of tau seeding activity in Alzheimer’s disease

(2018) Helmut Heinsen et al.   ACTA NEUROPATHOLOGICA

Which Memory System is Impaired First in Alzheimer's Disease?

(2018) Mira Didic et al.   JOURNAL OF ALZHEIMERS DISEASE

Selective and coherent activity increases due to stimulation indicate functional distinctions between episodic memory networks

(2018) Sungshin Kim et al.   Science Advances

Tau Accumulation in Clinically Normal Older Adults Is Associated with Hippocampal Hyperactivity

(2018) Willem Huijbers et al.   JOURNAL OF NEUROSCIENCE

The Relationship between Age, Neural Differentiation, and Memory Performance

(2018) Joshua D. Koen et al.   JOURNAL OF NEUROSCIENCE

Tau impairs neural circuits, dominating amyloid-β effects, in Alzheimer models in vivo

(2018) Marc Aurel Busche et al.   NATURE NEUROSCIENCE

Entorhinal Tau Pathology, Episodic Memory Decline, and Neurodegeneration in Aging

(2017) Anne Maass et al.   JOURNAL OF NEUROSCIENCE

Anterolateral Entorhinal Cortex Volume Predicted by Altered Intra-Item Configural Processing

(2017) Lok-Kin Yeung et al.   JOURNAL OF NEUROSCIENCE

Tau and β-Amyloid Are Associated with Medial Temporal Lobe Structure, Function, and Memory Encoding in Normal Aging

(2017) Shawn M. Marks et al.   JOURNAL OF NEUROSCIENCE

Integration of objects and space in perception and memory

(2017) Charles E Connor et al.   NATURE NEUROSCIENCE

Human anterolateral entorhinal cortex volumes are associated with cognitive decline in aging prior to clinical diagnosis

(2017) Rosanna K. Olsen et al.   NEUROBIOLOGY OF AGING

Amyloid and tau PET demonstrate region-specific associations in normal older people

(2017) Samuel N. Lockhart et al.   NEUROIMAGE

Comparison of multiple tau-PET measures as biomarkers in aging and Alzheimer's disease

(2017) Anne Maass et al.   NEUROIMAGE

Earliest accumulation of β-amyloid occurs within the default-mode network and concurrently affects brain connectivity

(2017) Sebastian Palmqvist et al.   Nature Communications

A protocol for manual segmentation of medial temporal lobe subregions in 7 Tesla MRI

(2017) D. Berron et al.   NeuroImage-Clinical

Dynamic relationships between age, amyloid-β deposition, and glucose metabolism link to the regional vulnerability to Alzheimer’s disease

(2016) Hwamee Oh et al.   BRAIN

Tau PET patterns mirror clinical and neuroanatomical variability in Alzheimer’s disease

(2016) Rik Ossenkoppele et al.   BRAIN

Greater loss of object than spatial mnemonic discrimination in aged adults

(2016) Zachariah M. Reagh et al.   HIPPOCAMPUS

Neuronal activity enhances tau propagation and tau pathology in vivo

(2016) Jessica W Wu et al.   NATURE NEUROSCIENCE

Evaluation of 2D multiband EPI imaging for high-resolution, whole-brain, task-based fMRI studies at 3T: Sensitivity and slice leakage artifacts

(2016) Nick Todd et al.   NEUROIMAGE

PET Imaging of Tau Deposition in the Aging Human Brain

(2016) Michael Schöll et al.   NEURON

PART is part of Alzheimer disease

(2015) Charles Duyckaerts et al.   ACTA NEUROPATHOLOGICA

Existing Pittsburgh Compound-B positron emission tomography thresholds are too high: statistical and pathological evaluation

(2015) Sylvia Villeneuve et al.   BRAIN

Cascading network failure across the Alzheimer’s disease spectrum

(2015) David T. Jones et al.   BRAIN

Prevalence of Amyloid PET Positivity in Dementia Syndromes

(2015) Rik Ossenkoppele et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Task-evoked fMRI changes in attention networks are associated with preclinical Alzheimer’s disease biomarkers

(2015) Brian A. Gordon et al.   NEUROBIOLOGY OF AGING

Aβ-related hyperactivation in frontoparietal control regions in cognitively normal elderly

(2015) Hwamee Oh et al.   NEUROBIOLOGY OF AGING

APOE-ε4 selectively modulates posteromedial cortex activity during scene perception and short-term memory in young healthy adults

(2015) J. P. Shine et al.   Scientific Reports

Functional topography of the human entorhinal cortex

(2015) Tobias Navarro Schröder et al.   eLife

Response of the medial temporal lobe network in amnestic mild cognitive impairment to therapeutic intervention assessed by fMRI and memory task performance

(2015) Arnold Bakker et al.   NeuroImage-Clinical

Primary age-related tauopathy (PART): a common pathology associated with human aging

(2014) John F. Crary et al.   ACTA NEUROPATHOLOGICA

Neuronal activity regulates extracellular tau in vivo

(2014) Kaoru Yamada et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Amyloid Deposition Is Linked to Aberrant Entorhinal Activity among Cognitively Normal Older Adults

(2014) W. Huijbers et al.   JOURNAL OF NEUROSCIENCE

Neural compensation in older people with brain amyloid-β deposition

(2014) Jeremy A Elman et al.   NATURE NEUROSCIENCE

Neural Specificity Predicts Fluid Processing Ability in Older Adults

(2013) J. Park et al.   JOURNAL OF NEUROSCIENCE

Trans-cellular Propagation of Tau Aggregation by Fibrillar Species

(2012) Najla Kfoury et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Two cortical systems for memory-guided behaviour

(2012) Charan Ranganath et al.   NATURE REVIEWS NEUROSCIENCE

Intact Memory for Irrelevant Information Impairs Perception in Amnesia

(2012) Morgan D. Barense et al.   NEURON

Reduction of Hippocampal Hyperactivity Improves Cognition in Amnestic Mild Cognitive Impairment

(2012) Arnold Bakker et al.   NEURON

Characterizing cognitive aging of recognition memory and related processes in animal models and in humans

(2012) Sara N. Burke et al.   Frontiers in Aging Neuroscience

The diagnosis of dementia due to Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer's disease

(2011) Guy M. McKhann et al.   Alzheimers & Dementia

The diagnosis of mild cognitive impairment due to Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer's disease

(2011) Marilyn S. Albert et al.   Alzheimers & Dementia

Amyloid- /Fyn-Induced Synaptic, Network, and Cognitive Impairments Depend on Tau Levels in Multiple Mouse Models of Alzheimer's Disease

(2011) E. D. Roberson et al.   JOURNAL OF NEUROSCIENCE

Neuronal activity regulates the regional vulnerability to amyloid-β deposition

(2011) Adam W Bero et al.   NATURE NEUROSCIENCE

A new neural framework for visuospatial processing

(2011) Dwight J. Kravitz et al.   NATURE REVIEWS NEUROSCIENCE

Age and amyloid-related alterations in default network habituation to stimulus repetition

(2011) Patrizia Vannini et al.   NEUROBIOLOGY OF AGING

Not quite PIB-positive, not quite PIB-negative: Slight PIB elevations in elderly normal control subjects are biologically relevant

(2011) Elizabeth C. Mormino et al.   NEUROIMAGE

Amyloid-β–induced neuronal dysfunction in Alzheimer's disease: from synapses toward neural networks

(2010) Jorge J Palop et al.   NATURE NEUROSCIENCE

High-resolution structural and functional MRI of hippocampal CA3 and dentate gyrus in patients with amnestic Mild Cognitive Impairment

(2010) Michael A. Yassa et al.   NEUROIMAGE

Functional-Anatomic Fractionation of the Brain's Default Network

(2010) Jessica R. Andrews-Hanna et al.   NEURON

Amyloid Deposition Is Associated with Impaired Default Network Function in Older Persons without Dementia

(2009) Reisa A. Sperling et al.   NEURON

The Brain's Default Network

(2008) Randy L. Buckner et al.   Annals of the New York Academy of Sciences

Clusters of Hyperactive Neurons Near Amyloid Plaques in a Mouse Model of Alzheimer's Disease

(2008) M. A. Busche et al.   SCIENCE