Structural tract alterations predict downstream tau accumulation in amyloid-positive older individuals

Harvard Aging Brain Study: Dataset and accessibility

(2017) Alexander Dagley et al.   NEUROIMAGE

Hyperphosphorylation determines both the spread and the morphology of tau pathology

(2016) Wen Hu et al.   Alzheimers & Dementia

The relationship between cerebrospinal fluid markers of Alzheimer pathology and positron emission tomography tau imaging

(2016) Brian A. Gordon et al.   BRAIN

In Vivo Tau, Amyloid, and Gray Matter Profiles in the Aging Brain

(2016) J. Sepulcre et al.   JOURNAL OF NEUROSCIENCE

Neuronal activity enhances tau propagation and tau pathology in vivo

(2016) Jessica W Wu et al.   NATURE NEUROSCIENCE

A critical appraisal of the pathogenic protein spread hypothesis of neurodegeneration

(2016) Dominic M. Walsh et al.   NATURE REVIEWS NEUROSCIENCE

Accelerated decline in white matter integrity in clinically normal individuals at risk for Alzheimer's disease

(2016) Anna Rieckmann et al.   NEUROBIOLOGY OF AGING

Aberrant functional connectivity differentiates retrosplenial cortex from posterior cingulate cortex in prodromal Alzheimer's disease

(2016) Kim N.H. Dillen et al.   NEUROBIOLOGY OF AGING

PET Imaging of Tau Deposition in the Aging Human Brain

(2016) Michael Schöll et al.   NEURON

Differential Time Course of Microstructural White Matter in Patients With Psychotic Disorder and Individuals at Risk: A 3-Year Follow-up Study

(2016) Patrick Domen et al.   SCHIZOPHRENIA BULLETIN

Evaluation of Tau Imaging in Staging Alzheimer Disease and Revealing Interactions Between β-Amyloid and Tauopathy

(2016) Liang Wang et al.   JAMA Neurology

Propagation of tau pathology: hypotheses, discoveries, and yet unresolved questions from experimental and human brain studies

(2015) Jada Lewis et al.   ACTA NEUROPATHOLOGICA

Validating novel tau positron emission tomography tracer [F-18]-AV-1451 (T807) on postmortem brain tissue

(2015) Marta Marquié et al.   ANNALS OF NEUROLOGY

Tau positron emission tomographic imaging in aging and early Alzheimer disease

(2015) Keith A. Johnson et al.   ANNALS OF NEUROLOGY

Asymmetries of amyloid-β burden and neuronal dysfunction are positively correlated in Alzheimer’s disease

(2015) Lars Frings et al.   BRAIN

The preclinical phase of the pathological process underlying sporadic Alzheimer’s disease

(2015) Heiko Braak et al.   BRAIN

Tau and neurodegenerative disease: the story so far

(2015) Khalid Iqbal et al.   Nature Reviews Neurology

Neuronal uptake and propagation of a rare phosphorylated high-molecular-weight tau derived from Alzheimer’s disease brain

(2015) Shuko Takeda et al.   Nature Communications

Amyloid accelerates tau propagation and toxicity in a model of early Alzheimer’s disease

(2015) Amy M Pooler et al.   Acta Neuropathologica Communications

A novel in vivo model of tau propagation with rapid and progressive neurofibrillary tangle pathology: the pattern of spread is determined by connectivity, not proximity

(2014) Zeshan Ahmed et al.   ACTA NEUROPATHOLOGICA

Frontal Cortical and Subcortical Projections Provide a Basis for Segmenting the Cingulum Bundle: Implications for Neuroimaging and Psychiatric Disorders

(2014) S. R. Heilbronner et al.   JOURNAL OF NEUROSCIENCE

Models of β-amyloid induced Tau-pathology: the long and “folded” road to understand the mechanism

(2014) Ilie-Cosmin Stancu et al.   Molecular Neurodegeneration

Amyloid and APOE  4 interact to influence short-term decline in preclinical Alzheimer disease

(2014) E. C. Mormino et al.   NEUROLOGY

Synergistic Effect of β-Amyloid and Neurodegeneration on Cognitive Decline in Clinically Normal Individuals

(2014) Elizabeth C. Mormino et al.   JAMA Neurology

Dissecting the uncinate fasciculus: disorders, controversies and a hypothesis

(2013) Rebecca J. Von Der Heide et al.   BRAIN

A concise radiosynthesis of the tau radiopharmaceutical, [18F]T807

(2013) Timothy M. Shoup et al.   JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS

Molecular drivers and cortical spread of lateral entorhinal cortex dysfunction in preclinical Alzheimer's disease

(2013) Usman A Khan et al.   NATURE NEUROSCIENCE

Cortical surface-based analysis reduces bias and variance in kinetic modeling of brain PET data

(2013) Douglas N. Greve et al.   NEUROIMAGE

Neurofibrillary tangle-bearing neurons are functionally integrated in cortical circuits in vivo

(2013) K. V. Kuchibhotla et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Asymmetry of neurodegenerative disease-related pathologies: a cautionary note

(2012) Harald Stefanits et al.   ACTA NEUROPATHOLOGICA

Propagation of Tau Pathology in a Model of Early Alzheimer's Disease

(2012) Alix de Calignon et al.   NEURON

Subjective cognitive complaints and amyloid burden in cognitively normal older individuals

(2012) Rebecca E. Amariglio et al.   NEUROPSYCHOLOGIA

Alzheimer’s pathogenesis: is there neuron-to-neuron propagation?

(2011) Heiko Braak et al.   ACTA NEUROPATHOLOGICA

Amyloid-Dependent and Amyloid-Independent Stages of Alzheimer Disease

(2011) Bradley T. Hyman   ARCHIVES OF NEUROLOGY

Partial volume effect as a hidden covariate in DTI analyses

(2011) Sjoerd B. Vos et al.   NEUROIMAGE

Aβ Accelerates the Spatiotemporal Progression of Tau Pathology and Augments Tau Amyloidosis in an Alzheimer Mouse Model

(2010) David E. Hurtado et al.   AMERICAN JOURNAL OF PATHOLOGY

Sequential relationships between grey matter and white matter atrophy and brain metabolic abnormalities in early Alzheimer's disease

(2010) N. Villain et al.   BRAIN

Transsynaptic Progression of Amyloid-β-Induced Neuronal Dysfunction within the Entorhinal-Hippocampal Network

(2010) Julie A. Harris et al.   NEURON

Disruption of Functional Connectivity in Clinically Normal Older Adults Harboring Amyloid Burden

(2009) T. Hedden et al.   JOURNAL OF NEUROSCIENCE

Cortical Hubs Revealed by Intrinsic Functional Connectivity: Mapping, Assessment of Stability, and Relation to Alzheimer's Disease

(2009) R. L. Buckner et al.   JOURNAL OF NEUROSCIENCE

About “axial” and “radial” diffusivities

(2009) Claudia A.M. Wheeler-Kingshott et al.   MAGNETIC RESONANCE IN MEDICINE

Transmission and spreading of tauopathy in transgenic mouse brain

(2009) Florence Clavaguera et al.   NATURE CELL BIOLOGY

What does the retrosplenial cortex do?

(2009) Seralynne D. Vann et al.   NATURE REVIEWS NEUROSCIENCE

Evaluation of 14 nonlinear deformation algorithms applied to human brain MRI registration

(2009) Arno Klein et al.   NEUROIMAGE

Cerebral White Matter Integrity and Cognitive Aging: Contributions from Diffusion Tensor Imaging

(2009) David J. Madden et al.   NEUROPSYCHOLOGY REVIEW

Stereotaxic white matter atlas based on diffusion tensor imaging in an ICBM template

(2008) Susumu Mori et al.   NEUROIMAGE