A subtype of oral, laryngeal, esophageal, and lung, squamous cell carcinoma with high levels of TrkB-T1 neurotrophin receptor mRNA
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Title
A subtype of oral, laryngeal, esophageal, and lung, squamous cell carcinoma with high levels of TrkB-T1 neurotrophin receptor mRNA
Authors
Keywords
NTRK2, TRKB-T1, Squamous cell carcinoma, NFE2L2, SOX2, PIK3CA, Sonic hedgehog
Journal
BMC CANCER
Volume 19, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2019-06-20
DOI
10.1186/s12885-019-5789-8
References
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Note: Only part of the references are listed.- Gene-expression signature regulated by the KEAP1-NRF2-CUL3 axis is associated with a poor prognosis in head and neck squamous cell cancer
- (2018) Akhileshwar Namani et al. BMC CANCER
- Pan-Cancer Molecular Classes Transcending Tumor Lineage Across 32 Cancer Types, Multiple Data Platforms, and over 10,000 Cases
- (2018) Fengju Chen et al. CLINICAL CANCER RESEARCH
- SOX2 regulation by hedgehog signaling controls adult lingual epithelium homeostasis
- (2018) David Castillo-Azofeifa et al. DEVELOPMENT
- Why Differentiation Therapy Sometimes Fails: Molecular Mechanisms of Resistance to Retinoids
- (2018) Petr Chlapek et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Astrocyte truncated-TrkB mediates BDNF antiapoptotic effect leading to neuroprotection
- (2018) Julieta Saba et al. JOURNAL OF NEUROCHEMISTRY
- Overexpression of PIK3CA in head and neck squamous cell carcinoma is associated with poor outcome and activation of the YAP pathway
- (2018) Ramón García-Escudero et al. ORAL ONCOLOGY
- TRKB tyrosine kinase receptor is a potential therapeutic target for poorly differentiated oral squamous cell carcinoma
- (2018) Kazumasa Moriwaki et al. Oncotarget
- SOX2 activation predicts prognosis in patients with head and neck squamous cell carcinoma
- (2018) Ji Hyun Chung et al. Scientific Reports
- Truncated TrkB.T1-Mediated Astrocyte Dysfunction Contributes to Impaired Motor Function and Neuropathic Pain after Spinal Cord Injury
- (2017) Jessica J. Matyas et al. JOURNAL OF NEUROSCIENCE
- Uncovering the role of brain-derived neurotrophic factor/tyrosine kinase receptor B signaling in head and neck malignancies
- (2017) Juliana Kern de Moraes et al. JOURNAL OF ORAL PATHOLOGY & MEDICINE
- New targets bring hope in squamous cell lung cancer: neurotrophic tyrosine kinase gene fusions
- (2017) Christian Rolfo et al. LABORATORY INVESTIGATION
- Brain-derived neurotrophic factor/tropomyosin-related kinase B signaling pathway contributes to the aggressive behavior of lung squamous cell carcinoma
- (2017) Keigo Ozono et al. LABORATORY INVESTIGATION
- PIK3CA mutations as prognostic factor in squamous cell lung carcinoma
- (2017) Marc McGowan et al. LUNG CANCER
- Enhancing GTEx by bridging the gaps between genotype, gene expression, and disease
- (2017) Barbara E Stranger et al. NATURE GENETICS
- Human neural stem/progenitor cells derived from the olfactory epithelium express the TrkB receptor and migrate in response to BDNF
- (2017) Leonardo Ortiz-López et al. NEUROSCIENCE
- JASPAR 2018: update of the open-access database of transcription factor binding profiles and its web framework
- (2017) Aziz Khan et al. NUCLEIC ACIDS RESEARCH
- NRF2-regulated metabolic gene signature as a prognostic biomarker in non-small cell lung cancer
- (2017) Akhileshwar Namani et al. Oncotarget
- TrkB promotes laryngeal cancer metastasis via activation PI3K/AKT pathway
- (2017) Liang Jiang et al. Oncotarget
- Characterizing gene sets using discriminative random walks with restart on heterogeneous biological networks
- (2016) Charles Blatti et al. BIOINFORMATICS
- Reduced mRNA expression levels of NFE2L2 are associated with poor outcome in breast cancer patients
- (2016) Barbara Wolf et al. BMC CANCER
- Neurogenin 3 is regulated by neurotrophic tyrosine kinase receptor type 2 (TRKB) signaling in the adult human exocrine pancreas
- (2016) Michael J. Shamblott et al. Cell Communication and Signaling
- Enrichr: a comprehensive gene set enrichment analysis web server 2016 update
- (2016) Maxim V. Kuleshov et al. NUCLEIC ACIDS RESEARCH
- Expression of nuclear factor, erythroid 2-like 2-mediated genes differentiates tuberculosis
- (2016) Zhongqing Qian et al. TUBERCULOSIS
- Tropomyosin-related kinase B/brain derived-neurotrophic factor signaling pathway as a potential therapeutic target for colorectal cancer
- (2016) Hussein Akil WORLD JOURNAL OF GASTROENTEROLOGY
- Hedgehog and TGFβ signaling converge on Gli2 to control bony invasion and bone destruction in oral squamous cell carcinoma
- (2016) Shellese A. Cannonier et al. Oncotarget
- The role of HPV RNA transcription, immune response-related gene expression and disruptiveTP53mutations in diagnostic and prognostic profiling of head and neck cancer
- (2015) Gunnar Wichmann et al. INTERNATIONAL JOURNAL OF CANCER
- TrkB Promotes Breast Cancer Metastasis via Suppression of Runx3 and Keap1 Expression
- (2015) MOLECULES AND CELLS
- p63 sustains self-renewal of mammary cancer stem cells through regulation of Sonic Hedgehog signaling
- (2015) Elisa Maria Memmi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Lung Cancer Incidence Trends by Gender, Race and Histology in the United States, 1973–2010
- (2015) Rafael Meza et al. PLoS One
- Nrf2 is Useful for Predicting the Effect of Chemoradiation Therapy on Esophageal Squamous Cell Carcinoma
- (2014) Yota Kawasaki et al. ANNALS OF SURGICAL ONCOLOGY
- Quiescent Sox2+ Cells Drive Hierarchical Growth and Relapse in Sonic Hedgehog Subgroup Medulloblastoma
- (2014) Robert J. Vanner et al. CANCER CELL
- The PRKCI and SOX2 Oncogenes Are Coamplified and Cooperate to Activate Hedgehog Signaling in Lung Squamous Cell Carcinoma
- (2014) Verline Justilien et al. CANCER CELL
- Sonic Hedgehog Signaling in Basal Cell Nevus Syndrome
- (2014) M. Athar et al. CANCER RESEARCH
- Sonic hedgehog signaling may promote invasion and metastasis of oral squamous cell carcinoma by activating MMP-9 and E-cadherin expression
- (2014) Hai-Xia Fan et al. MEDICAL ONCOLOGY
- SOX2 controls tumour initiation and cancer stem-cell functions in squamous-cell carcinoma
- (2014) Soufiane Boumahdi et al. NATURE
- Esophageal Carcinoma
- (2014) Anil K. Rustgi et al. NEW ENGLAND JOURNAL OF MEDICINE
- TRKing Down an Old Oncogene in a New Era of Targeted Therapy
- (2014) Aria Vaishnavi et al. Cancer Discovery
- SOX2 overexpression correlates with poor prognosis in laryngeal squamous cell carcinoma
- (2013) Xia-bing Tang et al. AURIS NASUS LARYNX
- Proteomic Analysis of Ubiquitin Ligase KEAP1 Reveals Associated Proteins That Inhibit NRF2 Ubiquitination
- (2013) B. E. Hast et al. CANCER RESEARCH
- The emerging role of the Nrf2-Keap1 signaling pathway in cancer
- (2013) M. C. Jaramillo et al. GENES & DEVELOPMENT
- TCPA: a resource for cancer functional proteomics data
- (2013) Jun Li et al. NATURE METHODS
- Molecular Subtypes in Head and Neck Cancer Exhibit Distinct Patterns of Chromosomal Gain and Loss of Canonical Cancer Genes
- (2013) Vonn Walter et al. PLoS One
- Upregulation of TrkB Promotes Epithelial-Mesenchymal Transition and Anoikis Resistance in Endometrial Carcinoma
- (2013) Wei Bao et al. PLoS One
- Integrative Analysis of Complex Cancer Genomics and Clinical Profiles Using the cBioPortal
- (2013) J. Gao et al. Science Signaling
- Copy Number Amplification of the PIK3CA Gene Is Associated with Poor Prognosis in Non-lymph node metastatic Head and Neck Squamous Cell Carcinoma
- (2012) Toshihito Suda et al. BMC CANCER
- Trks are novel oncogenes involved in the induction of neovascularization, tumor progression, and nodal metastasis in oral squamous cell carcinoma
- (2012) Tomonori Sasahira et al. CLINICAL & EXPERIMENTAL METASTASIS
- Truncated TrkB: Beyond a dominant negative receptor
- (2012) Barbara M. Fenner CYTOKINE & GROWTH FACTOR REVIEWS
- Disruption of SoxB1-Dependent Sonic hedgehog Expression in the Hypothalamus Causes Septo-optic Dysplasia
- (2012) Li Zhao et al. DEVELOPMENTAL CELL
- Expression of TrkB and BDNF is associated with poor prognosis in non-small cell lung cancer
- (2012) Kyoko Okamura et al. LUNG CANCER
- Cutoff Finder: A Comprehensive and Straightforward Web Application Enabling Rapid Biomarker Cutoff Optimization
- (2012) Jan Budczies et al. PLoS One
- The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data: Figure 1.
- (2012) Ethan Cerami et al. Cancer Discovery
- Brain-Derived Neurotrophic Factor and Neurotrophin-4/5 Are Expressed in Breast Cancer and Can Be Targeted to Inhibit Tumor Cell Survival
- (2011) E. Vanhecke et al. CLINICAL CANCER RESEARCH
- SOX2 gene amplification and protein overexpression are associated with better outcome in squamous cell lung cancer
- (2011) Theresia Wilbertz et al. MODERN PATHOLOGY
- Therapeutic targeting of Trk supresses tumor proliferation and enhances cisplatin activity in HNSCC
- (2010) Turker Yilmaz et al. CANCER BIOLOGY & THERAPY
- Lung Squamous Cell Carcinoma mRNA Expression Subtypes Are Reproducible, Clinically Important, and Correspond to Normal Cell Types
- (2010) M. D. Wilkerson et al. CLINICAL CANCER RESEARCH
- Human TrkB gene: novel alternative transcripts, protein isoforms and expression pattern in the prefrontal cerebral cortex during postnatal development
- (2010) Kristi Luberg et al. JOURNAL OF NEUROCHEMISTRY
- TrkB induces EMT and has a key role in invasion of head and neck squamous cell carcinoma
- (2010) M E Kupferman et al. ONCOGENE
- TrkBT1 Induces Liver Metastasis of Pancreatic Cancer Cells by Sequestering Rho GDP Dissociation Inhibitor and Promoting RhoA Activation
- (2009) Z. Li et al. CANCER RESEARCH
- Gene Expression Profiling Identifies Genes Predictive of Oral Squamous Cell Carcinoma
- (2008) C. Chen et al. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
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