SOX2 gene amplification and protein overexpression are associated with better outcome in squamous cell lung cancer

Progressive 3q Amplification Consistently TargetsSOX2in Preinvasive Squamous Lung Cancer

(2010) Frank McCaughan et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Sox2 Protein Expression is an Independent Poor Prognostic Indicator in Stage I Lung Adenocarcinoma

(2010) Lynette M. Sholl et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

SOX2 in Gastric Carcinoma, but not Hath1, is Related to Patients’ Clinicopathological Features and Prognosis

(2010) Xin Zhang et al.   JOURNAL OF GASTROINTESTINAL SURGERY

SOX2 Is an Oncogene Activated by Recurrent 3q26.3 Amplifications in Human Lung Squamous Cell Carcinomas

(2010) Thomas Hussenet et al.   PLoS One

Sex Determining Region Y-Box 2 (SOX2) Is a Potential Cell-Lineage Gene Highly Expressed in the Pathogenesis of Squamous Cell Carcinomas of the Lung

(2010) Ping Yuan et al.   PLoS One

Evidence That SOX2 Overexpression Is Oncogenic in the Lung

(2010) Yun Lu et al.   PLoS One

Recurrent copy number gain of transcription factorSOX2and corresponding high protein expression in oral squamous cell carcinoma

(2009) Kolja Freier et al.   GENES CHROMOSOMES & CANCER

SOX2 is highly expressed in squamous cell carcinomas of the gastrointestinal tract

(2009) Kevin B. Long et al.   HUMAN PATHOLOGY

The Yin and Yang of Sox proteins: Activation and repression in development and disease

(2009) Li-Jin Chew et al.   JOURNAL OF NEUROSCIENCE RESEARCH

SOX2 is an amplified lineage-survival oncogene in lung and esophageal squamous cell carcinomas

(2009) Adam J Bass et al.   NATURE GENETICS

The Increasing Complexity of the Cancer Stem Cell Paradigm

(2009) J. M. Rosen et al.   SCIENCE

Functional Evidence that the Self-Renewal GeneNANOGRegulates Human Tumor Development

(2009) Collene R. Jeter et al.   STEM CELLS

Sox2 Expression in Pulmonary Non-small Cell and Neuroendocrine Carcinomas

(2009) Lynette M. Sholl et al.   APPLIED IMMUNOHISTOCHEMISTRY & MOLECULAR MORPHOLOGY

Prognostic Significance of Epithelial-Mesenchymal and Mesenchymal-Epithelial Transition Protein Expression in Non-Small Cell Lung Cancer

(2008) A. Soltermann et al.   CLINICAL CANCER RESEARCH

Sox2 is important for two crucial processes in lung development: Branching morphogenesis and epithelial cell differentiation

(2008) Cristina Gontan et al.   DEVELOPMENTAL BIOLOGY

Clinical significance of TTF-1 protein expression andTTF-1gene amplification in lung adenocarcinoma

(2008) Justine A. Barletta et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

TTF1 expression in non-small cell lung carcinoma: association withTTF1gene amplification and improved survival

(2008) S Perner et al.   JOURNAL OF PATHOLOGY

Role of Chromosome 3q Amplification in Lung Cancer

(2008) Jun Qian et al.   Journal of Thoracic Oncology

An embryonic stem cell–like gene expression signature in poorly differentiated aggressive human tumors

(2008) Ittai Ben-Porath et al.   NATURE GENETICS

Chromosomal Abnormalities in Cancer

(2008) Stefan Fröhling et al.   NEW ENGLAND JOURNAL OF MEDICINE

Genomic profiling identifies TITF1 as a lineage-specific oncogene amplified in lung cancer

(2008) K A Kwei et al.   ONCOGENE