Preeclampsia may influence offspring neuroanatomy and cognitive function: a role for placental growth factor†

First-trimester screening for early and late preeclampsia using maternal characteristics, biomarkers, and estimated placental volume

(2018) Jiri Sonek et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Associations between maternal cytokine levels during gestation and measures of child cognitive abilities and executive functioning

(2018) Mikhail G. Dozmorov et al.   BRAIN BEHAVIOR AND IMMUNITY

Deoxycorticosterone acetate-salt hypertension activates placental growth factor in the spleen to couple sympathetic drive and immune system activation

(2018) Marialuisa Perrotta et al.   CARDIOVASCULAR RESEARCH

Placental hypoxia inducible factor -1α & CHOP immuno-histochemical expression relative to maternal circulatory syncytiotrophoblast micro-vesicles in preeclamptic and normotensive pregnancies

(2018) S. Verma et al.   European Journal of Obstetrics & Gynecology and Reproductive Biology

Placental growth factor, vascular endothelial growth factor, and hypoxia-inducible factor-1α in the placentas of women with pre-eclampsia

(2018) Lobna E. Ali et al.   Journal of Maternal-Fetal & Neonatal Medicine

Microglia, the missing link in maternal immune activation and fetal neurodevelopment; and a possible link in preeclampsia and disturbed neurodevelopment?

(2018) Jelmer R. Prins et al.   JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Long-term impacts of prenatal synthetic glucocorticoids exposure on functional brain correlates of cognitive monitoring in adolescence

(2018) Liesa Ilg et al.   Scientific Reports

Apparent systemic 11ß-dehydroxysteroid dehydrogenase 2 activity is increased in preeclampsia but not in intrauterine growth restriction

(2018) M. Vasku et al.   Pregnancy Hypertension-An International Journal of Womens Cardiovascular Health

Resting-state functional connectivity in children born from gestations complicated by preeclampsia: A pilot study cohort

(2018) Lauren E. Mak et al.   Pregnancy Hypertension-An International Journal of Womens Cardiovascular Health

Effects of placental growth factor deficiency on behavior, neuroanatomy and cerebrovasculature of mice

(2018) Vanessa R. Kay et al.   PHYSIOLOGICAL GENOMICS

Loss of placental growth factor ameliorates maternal hypertension and preeclampsia in mice

(2018) Jacqueline G. Parchem et al.   JOURNAL OF CLINICAL INVESTIGATION

Preeclampsia and academic performance in children: A nationwide study from Iceland

(2018) Fridgeir A. Sverrisson et al.   PLoS One

Fetal Growth and Placental Growth Factor Umbilical Cord Blood Levels

(2017) Zoe A. Broere-Brown et al.   FETAL DIAGNOSIS AND THERAPY

Levels of serum-circulating angiogenic factors within 1 week prior to delivery are closely related to conditions of pregnant women with pre-eclampsia, gestational hypertension, and/or fetal growth restriction

(2017) Sakiko Nanjo et al.   JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH

Performance of first trimester biochemical markers and mean arterial pressure in prediction of early-onset pre-eclampsia

(2017) Jaana Nevalainen et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Variants in the fetal genome near FLT1 are associated with risk of preeclampsia

(2017) Ralph McGinnis et al.   NATURE GENETICS

ASPRE trial: performance of screening for preterm pre-eclampsia

(2017) D. L. Rolnik et al.   ULTRASOUND IN OBSTETRICS & GYNECOLOGY

Neurovascular Interaction Promotes the Morphological and Functional Maturation of Cortical Neurons

(2017) Kun-Wei Wu et al.   Frontiers in Cellular Neuroscience

Combined screening for early and late pre-eclampsia and intrauterine growth restriction by maternal history, uterine artery Doppler, mean arterial pressure and biochemical markers

(2017) Ewelina Litwińska et al.   Advances in Clinical and Experimental Medicine

Neurological function in children born to preeclamptic and hypertensive mothers – A systematic review

(2017) Ernesto A. Figueiró-Filho et al.   Pregnancy Hypertension-An International Journal of Womens Cardiovascular Health

PLGF, a placental marker of fetal brain defects after in utero alcohol exposure

(2017) Matthieu Lecuyer et al.   Acta Neuropathologica Communications

Impact of preeclampsia on cognitive function in the offspring

(2016) Matthew T. Rätsep et al.   BEHAVIOURAL BRAIN RESEARCH

Secular Trends in Preeclampsia Incidence and Outcomes in a Large Canada Database: A Longitudinal Study Over 24 Years

(2016) Nathalie Auger et al.   CANADIAN JOURNAL OF CARDIOLOGY

Lower placental growth factor and higher free β-hCG and PAPP-A levels in the fetal circulation of near-term pregnancies complicated with severe preeclampsia

(2016) Verónica Paredes et al.   GYNECOLOGICAL ENDOCRINOLOGY

Fluid Shear Stress Promotes Placental Growth Factor Upregulation in Human Syncytiotrophoblast Through the cAMP–PKA Signaling PathwayNovelty and Significance

(2016) Edouard Lecarpentier et al.   HYPERTENSION

The effect of pre-eclampsia-like syndrome induced by L-NAME on learning and memory and hippocampal glucocorticoid receptor expression: A rat model

(2016) Hao Zhu et al.   HYPERTENSION IN PREGNANCY

The utilisation of operant delayed matching and non-matching to position for probing cognitive flexibility and working memory in mouse models of Huntington's disease

(2016) Emma Yhnell et al.   JOURNAL OF NEUROSCIENCE METHODS

Uterine artery pulsatility index at 12, 22, 32 and 36 weeks' gestation in screening for pre-eclampsia

(2016) N. O'Gorman et al.   ULTRASOUND IN OBSTETRICS & GYNECOLOGY

Hypertensive disorders during pregnancy and health outcomes in the offspring: a systematic review

(2016) T. V. Pinheiro et al.   Journal of Developmental Origins of Health and Disease

Prospective assessment of neurodevelopment in children following a pregnancy complicated by severe pre-eclampsia

(2016) Chelsie Warshafsky et al.   BMJ Open

Clinical risk factors for pre-eclampsia determined in early pregnancy: systematic review and meta-analysis of large cohort studies

(2016) Emily Bartsch et al.   BMJ-British Medical Journal

Clinical risk factors for pre-eclampsia determined in early pregnancy: systematic review and meta-analysis of large cohort studies

(2016) Emily Bartsch et al.   BMJ-British Medical Journal

Brain Structural and Vascular Anatomy Is Altered in Offspring of Pre-Eclamptic Pregnancies: A Pilot Study

(2015) M. T. Ra tsep et al.   AMERICAN JOURNAL OF NEURORADIOLOGY

Fetal endocrine and metabolic adaptations to hypoxia: the role of the hypothalamic-pituitary-adrenal axis

(2015) Elizabeth A. Newby et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Bioactive factors in uteroplacental and systemic circulation link placental ischemia to generalized vascular dysfunction in hypertensive pregnancy and preeclampsia

(2015) Dania A. Shah et al.   BIOCHEMICAL PHARMACOLOGY

Placental Growth Factor Influences Maternal Cardiovascular Adaptation to Pregnancy in Mice1

(2015) Kristiina L. Aasa et al.   BIOLOGY OF REPRODUCTION

Fetal sex dependency of maternal vascular adaptation to pregnancy: a prospective population-based cohort study

(2015) ZA Broere-Brown et al.   BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY

Preeclampsia: Syndrome or Disease?

(2015) Leslie Myatt et al.   CURRENT HYPERTENSION REPORTS

Early pregnancy maternal and fetal angiogenic factors and fetal and childhood growth: the Generation R Study

(2015) N.E. Bergen et al.   HUMAN REPRODUCTION

Influence of Maternal Angiogenic Factors During Pregnancy on Microvascular Structure in School-Age Children

(2015) O. Gishti et al.   HYPERTENSION

Cognitive Training Enhances Intrinsic Brain Connectivity in Childhood

(2015) D. E. Astle et al.   JOURNAL OF NEUROSCIENCE

Placental growth factor deficiency is associated with impaired cerebral vascular development in mice

(2015) Rayana Leal Luna et al.   MOLECULAR HUMAN REPRODUCTION

Developmental and Functional Brain Impairment in Offspring from Preeclampsia-Like Rats

(2015) Xueyuan Liu et al.   MOLECULAR NEUROBIOLOGY

Uterine artery blood flow, fetal hypoxia and fetal growth

(2015) V. A. Browne et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Glucocorticoid Metabolism in Hypertensive Disorders of Pregnancy: Analysis of Plasma and Urinary Cortisol and Cortisone

(2015) Katarzyna Kosicka et al.   PLoS One

The role of the dorsal hippocampus in two versions of the touchscreen automated paired associates learning (PAL) task for mice

(2015) Chi Hun Kim et al.   PSYCHOPHARMACOLOGY

Artificial oxygen carriers rescue placental hypoxia and improve fetal development in the rat pre-eclampsia model

(2015) Heng Li et al.   Scientific Reports

Preeclampsia, Placental Insufficiency, and Autism Spectrum Disorder or Developmental Delay

(2015) Cheryl K. Walker et al.   JAMA Pediatrics

Fetal Sex-Based Differences in Maternal Hormones, Angiogenic Factors, and Immune Mediators During Pregnancy and the Postpartum Period

(2014) Elizabeth Ann L. Enninga et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Maternal hypertensive disorders during pregnancy: adaptive functioning and psychiatric and psychological problems of the older offspring

(2014) S Tuovinen et al.   BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY

Pre-eclampsia and cardiovascular disease

(2014) C. W. Chen et al.   CARDIOVASCULAR RESEARCH

Maternal Preeclampsia and Risk for Cardiovascular Disease in Offspring

(2014) Guadalupe Herrera-Garcia et al.   CURRENT HYPERTENSION REPORTS

VEGF189 binds NRP1 and is sufficient for VEGF/NRP1-dependent neuronal patterning in the developing brain

(2014) M. Tillo et al.   DEVELOPMENT

Pre-eclampsia—An additional risk factor for cognitive impairment at school age after intrauterine growth restriction and very preterm birth

(2014) E. Morsing et al.   EARLY HUMAN DEVELOPMENT

The Angiogenic Factor PlGF Mediates a Neuroimmune Interaction in the Spleen to Allow the Onset of Hypertension

(2014) Daniela Carnevale et al.   IMMUNITY

HIF-1 Alpha and Placental Growth Factor in Pregnancies Complicated With Preeclampsia: A Qualitative and Quantitative Analysis

(2014) Gayatri Rath et al.   JOURNAL OF CLINICAL LABORATORY ANALYSIS

Transcriptional landscape of the prenatal human brain

(2014) Jeremy A. Miller et al.   NATURE

Maternal immune activation and abnormal brain development across CNS disorders

(2014) Irene Knuesel et al.   Nature Reviews Neurology

Maternal Pravastatin Prevents Altered Fetal Brain Development in a Preeclamptic CD-1 Mouse Model

(2014) Alissa R. Carver et al.   PLoS One

Maternal hypertensive diseases negatively affect offspring motor development

(2014) Tegan Grace et al.   Pregnancy Hypertension-An International Journal of Womens Cardiovascular Health

Sex differences in memory for landmark arrays in C57BL/J6 mice

(2013) Tania J. Bettis et al.   ANIMAL COGNITION

Navigation rules for vessels and neurons: cooperative signaling between VEGF and neural guidance cues

(2013) Sophie Chauvet et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Early-Life Glucocorticoid Exposure: The Hypothalamic-Pituitary-Adrenal Axis, Placental Function, and Long-term Disease Risk

(2013) Thorsten Braun et al.   ENDOCRINE REVIEWS

VEGF, PIGF and HIF-1α in placentas of early- and late-onset pre-eclamptic patients

(2013) Selda Demircan Sezer et al.   GYNECOLOGICAL ENDOCRINOLOGY

Spiral Artery Remodeling and Trophoblast Invasion in Preeclampsia and Fetal Growth Restriction

(2013) Fiona Lyall et al.   HYPERTENSION

The effect of maternal pravastatin therapy on adverse sensorimotor outcomes of the offspring in a murine model of preeclampsia

(2013) Alissa R. Carver et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE

Endothelial VEGF Sculpts Cortical Cytoarchitecture

(2013) S. Li et al.   JOURNAL OF NEUROSCIENCE

A preclinical cognitive test battery to parallel the National Institute of Health Toolbox in humans: bridging the translational gap

(2013) Shikha Snigdha et al.   NEUROBIOLOGY OF AGING

Evidence of sexual dimorphism in the placental function with severe preeclampsia

(2013) S. Muralimanoharan et al.   PLACENTA

Maternal hypertensive disorders in pregnancy and self-reported cognitive impairment of the offspring 70 years later: the Helsinki Birth Cohort Study

(2012) Soile Tuovinen et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Pre-eclampsia and offspring cardiovascular health: mechanistic insights from experimental studies

(2012) Esther F. Davis et al.   CLINICAL SCIENCE

Uterine natural killer cells initiate spiral artery remodeling in human pregnancy

(2012) Andrew Robson et al.   FASEB JOURNAL

Newborns of Preeclamptic Women Show Evidence of Sex-Specific Disparity in Fetal Growth

(2012) Simone A. Reynolds et al.   Gender Medicine

Low Placental Growth Factor Across Pregnancy Identifies a Subset of Women With Preterm Preeclampsia

(2012) Robert W. Powers et al.   HYPERTENSION

Midtrimester amniotic fluid concentrations of angiogenic factors in relation to maternal, gestational and neonatal characteristics in normal pregnancies

(2012) Thalis Papapostolou et al.   Journal of Maternal-Fetal & Neonatal Medicine

The neurocognitive outcome of IUGR children born to mothers with and without preeclampsia

(2012) Y. Leitner et al.   Journal of Maternal-Fetal & Neonatal Medicine

Astrocytes Control the Development of the Migration-Promoting Vasculature Scaffold in the Postnatal Brain via VEGF Signaling

(2012) L. Bozoyan et al.   JOURNAL OF NEUROSCIENCE

Hypertensive disorders in pregnancy and cognitive decline in the offspring up to old age

(2012) S. Tuovinen et al.   NEUROLOGY

Do hypertensive diseases of pregnancy disrupt neurocognitive development in offspring?

(2012) Andrew J. O. Whitehouse et al.   PAEDIATRIC AND PERINATAL EPIDEMIOLOGY

Resource allocation in utero and health in later life

(2012) D.J.P. Barker et al.   PLACENTA

Outcome at 4.5 years of children born after expectant management of early-onset hypertensive disorders of pregnancy

(2011) Aleid G. van Wassenaer et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Hypertensive disorders in pregnancy and intellectual abilities in the offspring in young adulthood: The Helsinki Birth Cohort Study

(2011) Soile Tuovinen et al.   ANNALS OF MEDICINE

Increased expression of placental growth factor in patients with temporal lobe epilepsy and a rat model

(2011) Yali Xu et al.   BRAIN RESEARCH

VEGF signalling controls GnRH neuron survival via NRP1 independently of KDR and blood vessels

(2011) A. Cariboni et al.   DEVELOPMENT

Hypertensive disorders in pregnancy and risk of severe mental disorders in the offspring in adulthood: The Helsinki Birth Cohort Study

(2011) Soile Tuovinen et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Increased Placental Growth Factor in Cerebrospinal Fluid of Patients with Epilepsy

(2011) Yali Xu et al.   NEUROCHEMICAL RESEARCH

Brain Connectivity

(2011) Gaolang Gong et al.   NEUROSCIENTIST

Prediction of Neurodevelopmental and Sensory Outcome at 5 Years in Norwegian Children Born Extremely Preterm

(2011) K. T. Leversen et al.   PEDIATRICS

Impact of chorioamnionitis and preeclampsia on neurodevelopmental outcome in preterm infants below 32 weeks gestational age

(2010) Luregn J Schlapbach et al.   ACTA PAEDIATRICA

The “Great Obstetrical Syndromes” are associated with disorders of deep placentation

(2010) Ivo Brosens et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Depressive symptoms in adulthood and intrauterine exposure to pre-eclampsia: the Helsinki Birth Cohort Study

(2010) S Tuovinen et al.   BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY

Circulating cytokines, chemokines and adhesion molecules in normal pregnancy and preeclampsia determined by multiplex suspension array

(2010) Andras Szarka et al.   BMC IMMUNOLOGY

Vascular endothelial growth factor signaling implicated in neuroprotective effects of placental growth factor in an in vitro ischemic model

(2010) Huan Du et al.   BRAIN RESEARCH

Prenatal stress and brain development

(2010) Arnaud Charil et al.   BRAIN RESEARCH REVIEWS

Sex- and Brain Size–Related Small-World Structural Cortical Networks in Young Adults: A DTI Tractography Study

(2010) Chaogan Yan et al.   CEREBRAL CORTEX

Rewirable gene regulatory networks in the preimplantation embryonic development of three mammalian species

(2010) D. Xie et al.   GENOME RESEARCH

Are Maternal Genitourinary Infection and Pre-Eclampsia Associated With ADHD in School-Aged Children?

(2010) Joshua R. Mann et al.   Journal of Attention Disorders

Maternal activating KIRs protect against human reproductive failure mediated by fetal HLA-C2

(2010) Susan E. Hiby et al.   JOURNAL OF CLINICAL INVESTIGATION

Perinatal asphyxia is associated with the umbilical cord nucleated red blood cell count in pre-eclamptic pregnancies

(2010) F. Bayram et al.   JOURNAL OF OBSTETRICS AND GYNAECOLOGY

Pre-eclampsia: fitting together the placental, immune and cardiovascular pieces

(2010) Joanna L James et al.   JOURNAL OF PATHOLOGY

Treatment with sildenafil prevents impairment of learning in rats born to pre-eclamptic mothers

(2010) O. Cauli et al.   NEUROSCIENCE

Functional Assays for Neurotoxicity Testing

(2010) Virginia C. Moser   TOXICOLOGIC PATHOLOGY

Pregnancy-associated Hypertensive Disorders and Adult Cognitive Function Among Danish Conscripts

(2009) V. Ehrenstein et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Evidence for Immune Cell Involvement in Decidual Spiral Arteriole Remodeling in Early Human Pregnancy

(2009) Samantha D. Smith et al.   AMERICAN JOURNAL OF PATHOLOGY

Rheological and Physiological Consequences of Conversion of the Maternal Spiral Arteries for Uteroplacental Blood Flow during Human Pregnancy

(2009) G.J. Burton et al.   PLACENTA

Pre-Eclampsia Is Associated With Increased Risk of Stroke in the Adult Offspring

(2009) Eero Kajantie et al.   STROKE

Hypertensive Diseases of Pregnancy and the Development of Behavioral Problems in Childhood and Adolescence: The Western Australian Pregnancy Cohort Study

(2008) Monique Robinson et al.   JOURNAL OF PEDIATRICS

High resolution three-dimensional brain atlas using an average magnetic resonance image of 40 adult C57Bl/6J mice

(2008) A.E. Dorr et al.   NEUROIMAGE

Preeclampsia and Risk for Epilepsy in Offspring

(2008) C. S. Wu et al.   PEDIATRICS