Withaferin A reverses bile duct ligation‐induced liver fibrosis by modulating extracellular matrix deposition: Role of LOXL2/Snail1, vimentin, and NFκB signaling

Cerulein-induced chronic pancreatitis in Swiss albino mice: An improved short-term model for pharmacological screening

(2019) Sapana Bansod et al.   JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS

Modulation of cerulein‐induced pancreatic inflammation by hydroalcoholic extract of curry leaf ( Murraya koenigii )

(2019) Amit Khurana et al.   PHYTOTHERAPY RESEARCH

Dramatic improvement in pharmacokinetic and pharmacodynamic effects of sustain release curcumin microparticles demonstrated in experimental type 1 diabetes model

(2019) Pratibha Anchi et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Therapeutic applications of selenium nanoparticles

(2019) Amit Khurana et al.   BIOMEDICINE & PHARMACOTHERAPY

Visnagin attenuates acute pancreatitis via Nrf2/NFκB pathway and abrogates associated multiple organ dysfunction

(2019) Lakshmi Priya Pasari et al.   BIOMEDICINE & PHARMACOTHERAPY

Withaferin A ameliorates renal injury due to its potent effect on inflammatory signaling

(2019) Chandra S. Peddakkulappagari et al.   BIOFACTORS

Yttrium oxide nanoparticles reduce the severity of acute pancreatitis caused by cerulein hyperstimulation

(2019) Amit Khurana et al.   Nanomedicine-Nanotechnology Biology and Medicine

Nimbolide ameliorates unilateral ureteral obstruction-induced renal fibrosis by inhibition of TGF-β and EMT/Slug signalling

(2019) Shivaraju Annaldas et al.   MOLECULAR IMMUNOLOGY

The apparent competitive action of ECM proteases and cross-linking enzymes during fibrosis: Applications to drug discovery

(2018) Nikolaos A. Afratis et al.   ADVANCED DRUG DELIVERY REVIEWS

Andrographolide ameliorates silica induced pulmonary fibrosis

(2018) Sachin Karkale et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

First report on the pharmacokinetic profile of nimbolide, a novel anticancer agent in oral and intravenous administrated rats by LC/MS method

(2018) Shandilya Mahamuni Baira et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Sustained Release Curcumin Microparticles (CuMPs) for Effective Prophylactic Treatment of Exocrine Dysfunction of Pancreas: A Preclinical Study in Cerulein Induced Acute Pancreatitis

(2018) Pratibha Anchi et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Cardioprotective effects of nanoceria in a murine model of cardiac remodeling

(2018) Preeti Kumari et al.   JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY

Nanoceria ameliorates doxorubicin induced cardiotoxicity: Possible mitigation via reduction of oxidative stress and inflammation

(2018) Swetha Sangomla et al.   JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY

Isoproterenol-induced cardiac ischemia and fibrosis: Plant-based approaches for intervention

(2018) Prince Allawadhi et al.   PHYTOTHERAPY RESEARCH

Oropharyngeal administration of silica in Swiss mice: A robust and reproducible model of occupational pulmonary fibrosis

(2018) Sachin Karkale et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS

Nimbolide epigenetically regulates autophagy and apoptosis in breast cancer

(2018) Venkatesh Pooladanda et al.   TOXICOLOGY IN VITRO

Protective Effect of Nanoceria on Cisplatin-Induced Nephrotoxicity by Amelioration of Oxidative Stress and Pro-inflammatory Mechanisms

(2018) Mohd Aslam Saifi et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

Withaferin-A attenuates multiple low doses of Streptozotocin (MLD-STZ) induced type 1 diabetes

(2018) Sravani Tekula et al.   BIOMEDICINE & PHARMACOTHERAPY

Nanoceria suppresses multiple low doses of streptozotocin-induced Type 1 diabetes by inhibition of Nrf2/NF-κB pathway and reduction of apoptosis

(2018) Amit Khurana et al.   Nanomedicine

Withaferin A, a novel compound of Indian ginseng (Withania somnifera ), ameliorates Cerulein-induced acute pancreatitis: Possible role of oxidative stress and inflammation

(2018) Vijaya Lakshmi Tiruveedi et al.   PHYTOTHERAPY RESEARCH

Selective targeting of lysyl oxidase-like 2 (LOXL2) suppresses hepatic fibrosis progression and accelerates its reversal

(2017) Naoki Ikenaga et al.   GUT

Overview on Therapeutic Applications of Microparticulate Drug Delivery Systems

(2016) Swarna Bale et al.   CRITICAL REVIEWS IN THERAPEUTIC DRUG CARRIER SYSTEMS

Lysyl oxidase-like 2 (LOXL2) oxidizes trimethylated lysine 4 in histone H3

(2016) Nicolás Herranz et al.   FEBS Journal

Hepatoprotective and Anti-fibrotic Agents: It's Time to Take the Next Step

(2016) Ralf Weiskirchen   Frontiers in Pharmacology

Withaferin-A Reduces Acetaminophen-Induced Liver Injury in Mice

(2015) Ravirajsinh N. Jadeja et al.   BIOCHEMICAL PHARMACOLOGY

Protective effect of gastrodin on bile duct ligation-induced hepatic fibrosis in rats

(2015) Shuangshuang Zhao et al.   FOOD AND CHEMICAL TOXICOLOGY

Tu1889 Administration of Withaferin a Protects Mice From Cerulein-Induced Pancreatitis

(2015) Mazhar A. Kanak et al.   GASTROENTEROLOGY

Vimentin Phosphorylation Underlies Myofibroblast Sensitivity to Withaferin A In Vitro and during Corneal Fibrosis

(2015) Paola Bargagna-Mohan et al.   PLoS One

Liver cirrhosis mortality in 187 countries between 1980 and 2010: a systematic analysis

(2014) Ali A Mokdad et al.   BMC Medicine

Selenium nanoparticles involve HSP-70 and SIRT1 in preventing the progression of type 1 diabetic nephropathy

(2014) Goru Santosh Kumar et al.   CHEMICO-BIOLOGICAL INTERACTIONS

The Role of Snail in EMT and Tumorigenesis

(2014) Yifan Wang et al.   CURRENT CANCER DRUG TARGETS

Lysyl oxidase-like 2 (LOXL2) and E47 EMT factor: novel partners in E-cadherin repression and early metastasis colonization

(2014) G Canesin et al.   ONCOGENE

Cellular and molecular mechanisms in the pathogenesis of liver fibrosis: An update

(2014) Gülsüm Özlem Elpek   WORLD JOURNAL OF GASTROENTEROLOGY

Hepatic Localization of Macrophage Phenotypes during Fibrogenesis and Resolution of Fibrosis in Mice and Humans

(2014) Leonie Beljaars et al.   Frontiers in Immunology

Evolving therapies for liver fibrosis

(2013) Detlef Schuppan et al.   JOURNAL OF CLINICAL INVESTIGATION

Pathogenesis of Liver Fibrosis

(2011) Virginia Hernandez-Gea et al.   Annual Review of Pathology-Mechanisms of Disease

Withaferin A induces apoptosis in human melanoma cells through generation of reactive oxygen species and down-regulation of Bcl-2

(2011) Eleonore Mayola et al.   APOPTOSIS

Withaferin A inhibits breast cancer invasion and metastasis at sub-cytotoxic doses by inducing vimentin disassembly and serine 56 phosphorylation

(2011) Jose T. Thaiparambil et al.   INTERNATIONAL JOURNAL OF CANCER

A Novel Role of Vimentin Filaments: Binding and Stabilization of Collagen mRNAs

(2011) A. A. Challa et al.   MOLECULAR AND CELLULAR BIOLOGY

IKKα and IKKβ Each Function to Regulate NF-κB Activation in the TNF-Induced/Canonical Pathway

(2010) Mazhar Adli et al.   PLoS One

The Hypoxia-controlled FBXL14 Ubiquitin Ligase Targets SNAIL1 for Proteasome Degradation

(2009) Rosa Viñas-Castells et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inhibition of NFκB by the natural product Withaferin A in cellular models of Cystic Fibrosis inflammation

(2009) Rangan Maitra et al.   Journal of Inflammation-London