Article
Biochemistry & Molecular Biology
Chunling Wei, Peiwu Cui, Xiangqian Liu
Summary: Antibacterial resistance is a serious global health problem, and scientists are focusing on developing new antibacterial drugs from natural products. This study investigated the antibacterial activity and mechanism of madecassic acid (MA), a compound isolated from Chinese medicine. It was found that MA had inhibitory effects on eight pathogenic bacteria, with a minimum inhibitory concentration of 31.25μg/mL for Staphylococcus aureus.
Article
Food Science & Technology
Yawei Ning, Linlin Hou, Mengge Ma, Mingrui Li, Zhongqing Zhao, Dongchun Zhang, Zhixin Wang, Yingmin Jia
Summary: Sucrose laurate (SL) is a dual-functional additive with emulsifying and antibacterial activities. The synergistic antibacterial mechanism of SL and nisin were studied against Staphylococcus aureus. This research provides insights into broadening the application of SL in food industry.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2022)
Article
Food Science & Technology
Deyin Zhao, Qian Wang, Fengxia Lu, Xiaomei Bie, Haizhen Zhao, Zhaoxin Lu, Yingjian Lu
Summary: Plantaricin 827, a novel bacteriocin, has been found to effectively inhibit S. aureus and significantly extend the shelf life of skim milk. Its antibacterial mechanism involves increasing cell membrane permeability, inhibiting biofilm formation, and interacting with genomic DNA minor groove in AT-rich regions.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2022)
Review
Biochemistry & Molecular Biology
Lutfun Nahar, Afaf Al-Groshi, Anil Kumar, Satyajit D. Sarker
Summary: Arbutin, a natural skin-whitening agent, shows potential therapeutic properties in addition to its skin whitening effect. This article provides a comprehensive overview of the distribution of arbutin in plants and critically evaluates its potential as an anticancer agent based on published literature.
Article
Food Science & Technology
Hui Li, Yan-yan Huang, Keren Agyekumwaa Addo, Ze-xuan Huang, Yi-gang Yu, Xing-long Xiao
Summary: This study revealed the stress response mechanism of S. aureus under CUM pressure, providing a theoretical basis for the application of CUM in meat products.
INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY
(2022)
Article
Food Science & Technology
Jinming Dai, Mei Bai, Changzhu Li, Wai San Cheang, Haiying Cui, Lin Lin
Summary: This study aimed to investigate the impact of citral concentration on its antibacterial effect against Staphylococcus aureus. The results showed that citral at a concentration of 0.5 mg/mL significantly disturbed the cell membrane fluidity and permeability, leading to cell death. However, at a concentration of 0.25 mg/mL, the membrane damage was reduced and a complex interaction between citral and the membrane components was observed. Overall, this study provides valuable insights into the antibacterial mechanisms of natural compounds and expands the potential applications of citral as a natural antimicrobial.
Article
Food Science & Technology
Weijun Leng, Xiaoyun Wu, Tong Shi, Zhiyu Xiong, Li Yuan, Wengang Jin, Ruichang Gao
Summary: The skin mucus extract of Channa argus possesses strong inhibitory action against Staphylococcus aureus, disrupting cell membrane functions to induce intracellular metabolic imbalance and affecting the normal physiological functions and growth of the bacteria. The antimicrobial mechanism involves inhibiting primary metabolic pathways of the bacteria such as the tricarboxylic acid cycle and amino acid biosynthesis.
Article
Biochemistry & Molecular Biology
Yong Guo, Ruige Yang, Fangfang Chen, Tingting Yan, Tingyu Wen, Fang Li, Xiaoyu Su, Lei Wang, Juan Du, Jifeng Liu
Summary: In this study, three triphenyl-sesquineolignans were isolated and seven derivatives were prepared. Compound 6 showed the best antibacterial activity against Gram-positive bacteria and clinical MRSA strains, with low drug resistance development probability and hemolysis. Mechanism studies revealed that compound 6 kills bacterial strains by disrupting membranes, indicating its potential as a new antibacterial candidate for combating MRSA infections.
BIOORGANIC CHEMISTRY
(2021)
Article
Microbiology
Yanhui Hu, Yuyuan Xing, Peng Ye, Haikuan Yu, Xianglei Meng, Yuting Song, Gongying Wang, Yanyan Diao
Summary: Ionic liquids (ILs) have been gaining attention in the biomedical field due to their unique properties. However, there is still a lack of understanding of their potential applications and underlying principles. We evaluated the antibacterial activity and mechanism of imidazole chloride ILs on Staphylococcus aureus, finding that the length of the imidazolidinyl side chain positively correlated with ILs toxicity. C12MIMCl caused bacterial death by simultaneously affecting the internal and external parts of S. aureus, stimulating oxidative stress and destroying the cell membrane.
FRONTIERS IN MICROBIOLOGY
(2023)
Article
Food Science & Technology
Hui Yang, Xiangjun Zhan, Luyi Song, Shuai Cheng, Ruiying Su, Yingying Zhang, Du Guo, Xin Lu, Xiaodong Xia, Chao Shi
Summary: This study investigated the antibacterial and antibiofilm mechanism of ultrasound combined with citral nanoemulsion against Staphylococcus aureus and mature biofilm. The combination treatment disrupted cell membrane integrity and permeability, enhanced cellular oxidative stress and membrane lipid peroxidation, and resulted in cell rupture and collapse. In addition, the treatment showed a more pronounced removal effect than both alone in the biofilm on the stainless steel sheet. This research provides a safe and efficient sterilization method for the food industry.
INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY
(2023)
Article
Food Science & Technology
Mengyuan Qi, Ruoqing Zhao, Qingyan Liu, Haiyang Yan, Yan Zhang, Shiyi Wang, Yuan Yuan
Summary: The inhibitory effects of three types of electric fields on Staphylococcus aureus were investigated, with prick electrostatic field (HVPEF) showing the most sensitivity and effectiveness in damaging cell membrane and increasing cell permeability. This technology has potential applications in non-thermal food sterilization.
Article
Chemistry, Medicinal
Dingyi Shen, Songpo Duan, Yuhan Hu, Jintong Liang, Youzhi Tang
Summary: This study found that the phloroglucinol derivative TPG and 2-nitrophloroglucinol exhibited potent synergistic antibacterial activity with penicillin or bacitracin against MRSA. The combination disrupted the MRSA cell membrane and inhibited the expression of related proteins, effectively inhibiting MRSA growth.
PHYTOTHERAPY RESEARCH
(2023)
Article
Food Science & Technology
Jun Li, Changzhu Li, Ce Shi, Javad Aliakbarlu, Haiying Cui, Lin Lin
Summary: This study investigated the antibacterial mechanisms of clove essential oil (CEO) against Staphylococcus aureus and evaluated its efficacy in pork preservation. It was found that CEO damaged the morphology of Staphylococcus aureus cells and led to leakage of intracellular components. At the metabolic level, CEO significantly inhibited the respiratory metabolism of Staphylococcus aureus. Molecular biology experiments showed that CEO interacted with Staphylococcus aureus DNA molecules and affected the expression of virulence genes. Application results demonstrated the good antibacterial effect of CEO in pork preservation without affecting its texture.
INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY
(2022)
Article
Agriculture, Multidisciplinary
Hang Sun, Mohammad Fawad Ansari, Bo Fang, Cheng-He Zhou
Summary: Berberine-hybridized benzimidazoles, such as the 2,4-dichlorobenzyl derivative 7d, showed potent antibacterial efficacy against Staphylococcus aureus, with the ability to eradicate bacterial biofilm and low toxicity towards mammalian cells. Combination with norfloxacin enhanced the antibacterial efficacy, while development of bacterial resistance was not observed. Mechanism studies indicated that the active molecule 7d damaged membrane integrity, stimulated ROS generation, and bound with DNA and S. aureus sortase A, exerting powerful antibacterial ability in treating S. aureus in the livestock industry.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2021)
Article
Chemistry, Medicinal
Binru Yin, Xisha Lin, Ting Wang, Li Liu
Summary: Human milk N-glycome exhibits strong antibacterial activity against Staphylococcus aureus by targeting the bacterial cell surface.
ACS INFECTIOUS DISEASES
(2022)
Article
Environmental Sciences
Hongchuan Li, Rui Jin, Zhaowen Xu, Hongxiang Hu, Yusef Kianpoor Kalkhajeh, Yingying Zhao, Linchuan Zhan
Summary: In this study, the potential of chelate tetrasodium glutamate diacetate (GLDA) combined with Tagetes patula L. to remediate cadmium-contaminated soil was investigated. The results showed that GLDA application significantly increased the biomass and cadmium content of Tagetes patula, indicating the efficacy of GLDA for the remediation of cadmium-contaminated farmlands.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Engineering, Electrical & Electronic
Tongchuan Chen, Yingying Zhao, Qianqian Wang, Wenting Wang, Aimin An
Summary: This paper proposes a Distributed Secondary Compensation Control (DSCC) method to solve the problems of the transmission system controlled by traditional droop control. It improves the dynamic response of the system and its fault ride through capability.
JOURNAL OF ELECTRICAL ENGINEERING & TECHNOLOGY
(2023)
Article
Chemistry, Applied
Ying-Ying Zhao, Yu-Jie Li, Xiao-Mei Yu, Qin-Ting Su, Li-Wen Wang, Yu-Shu Zhu, Yan-Hui Fu, Guang-Ying Chen, Yan-Ping Liu
Summary: A new bisabolane-type sesquiterpenoid, morincitrinoid A (1), was isolated from the stems and leaves of Morinda citrifolia L., along with five known analogues (2-6), through phytochemical study. The chemical structure of 1 was determined by comprehensive spectral analysis. Compounds 1-6 exhibited significant anti-inflammatory and anti-HIV activities, inhibiting NO production and HIV-1 reverse transcriptase (RT) with comparable or better potency than hydrocortisone, indicating their potential therapeutic value.
NATURAL PRODUCT RESEARCH
(2023)
Article
Pharmacology & Pharmacy
Shuai-Bing Liu, Xia Yao, Jun Tao, Jian-Jun Yang, Ying-Ying Zhao, Dong-Wei Liu, Su-Yun Wang, Su-Ke Sun, Xu Wang, Pang-Ke Yan, Nan Wu, Xiao Liu, Xiao-Jian Zhang, Xin Tian, Zhang-Suo Liu
Summary: The aim of this study was to develop a population pharmacokinetic (PK) model for ciprofol and its major metabolite M4, and link it to the population pharmacodynamics (PD) model in subjects with different renal functions. The study found that the PK of ciprofol and M4 could be best described by three-compartment and two-compartment models, respectively. The concentrations of ciprofol and M4 were linked using a linear protein binding model. Hemoglobin and uric acid were identified as covariates affecting the clearance of ciprofol and M4. The developed model provides a comprehensive understanding of the PK and PD of ciprofol.
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
(2023)
Review
Physics, Multidisciplinary
Sayantan Mazumdar, Ying Zhao, Xiaodan Zhang
Summary: Perovskite/silicon tandem solar cells (PSTSCs) have the potential to overcome the efficiency limit of single-junction silicon solar cells by combining the wider bandgap of a semitransparent perovskite solar cell (PSC) with the ability of a narrow bandgap silicon solar cell to convert infrared light. However, the actual efficiency of PSTSCs is currently below the theoretical limit, and challenges in stability and upscaling need to be addressed.
SCIENCE CHINA-PHYSICS MECHANICS & ASTRONOMY
(2023)
Article
Environmental Sciences
Zirui Ye, Miao Qi, Yingming Zhao, Wei Wei, X. George Xu
Summary: This study estimated the fetal and pediatric doses from chest CT scans performed during the COVID-19 pandemic. Organ and effective doses were calculated using VirtualDose-CT software. The results showed that fetal absorbed doses ranged from 0.04 to 0.61 mGy depending on the gestational age, and extending the scan range to the abdominal region increased fetal doses by almost 4-fold. The findings provide valuable information for radiologists and patients to minimize unnecessary radiation exposure.
RADIATION PROTECTION DOSIMETRY
(2023)
Article
Chemistry, Physical
Liang Yan, Qiao Yuan, Hui Tian, Wanzhong Ren, Lei Wang, Yingchun Zhao
Summary: Mo-Bi based catalysts have attracted attention for the oxidation reaction of isobutene to methacrolein. Most studies focus on the reaction mechanism and catalytic active sites, but fail to reflect the real reaction process on commercial catalyst surfaces. This research demonstrates that fine-tuning the active phase structure can greatly enhance the catalytic performances, providing a new perspective for developing high-performance catalysts.
REACTION KINETICS MECHANISMS AND CATALYSIS
(2023)
Article
Environmental Sciences
Kaixin Zheng, Yufen Wang, Xiaomin Wang, Tingting Zhu, Xueming Chen, Yingxin Zhao, Peizhe Sun, Yindong Tong, Yiwen Liu
Summary: This survey investigated the influence of ultrasound (US) and potassium permanganate (KMnO4) co-pretreatment on anaerobic digestion of waste activated sludge (WAS). The results showed that the co-treatment significantly increased the cumulative methane yield and improved the biodegradability of soluble organics. The analysis also revealed that US + KMnO4 pretreatment enhanced the biochemical methane potential, hydrolysis rate, and relative abundance of functional microorganisms associated with anaerobic digestion.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Chemistry, Multidisciplinary
Lu Jin, Ningyu Ren, Pengyang Wang, Renjie Li, Qifan Xue, Fei Huang, Xiaobo Zhang, Ying Zhao, Xiaodan Zhang
Summary: A secondary anti-solvent strategy is proposed for the first time to further reduce surface defects in conventional surface passivation for perovskite solar cells. This strategy effectively enhances the crystallization quality of 2D perovskite and reduces the surface defect density by nearly two orders.
Article
Environmental Sciences
Yingying Zhao, Meng Su, Xin Meng, Jiying Liu, Faming Wang
Summary: This study evaluated the effects of environmental heat stress and personal cooling strategies on the physiological and perceptual responses of college students wearing personal protective equipment (PPE). The results showed that PPE can help mitigate heat stress, and the use of cooling systems can further reduce heat strain. The perceptual responses improved significantly with the use of personal cooling systems.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2023)
Article
Genetics & Heredity
Xiaochen Zhu, Yingying Zhao, Hua Wei, Nan Hu, Qingbiao Hu, Yingdong Li
Summary: In this study, the complete mitochondrial genome of the poorly understood leech species Torix tukubana was sequenced using next-generation sequencing. The results showed that the mitogenome consisted of 13 protein-coding genes, 22 tRNAs, 2 rRNAs, and 1 control region. The phylogenetic analysis indicated that T. tukubana belonged to the monophyletic group of Glossiphoniidae, consistent with previous research.
Article
Chemistry, Multidisciplinary
Sanjiang Pan, Renjie Li, Jin Wang, Qixing Zhang, Manjing Wang, Biao Shi, Pengyang Wang, Ying Zhao, Xiaodan Zhang
Summary: In this paper, a two-dimensional nanosheet quaternary metal hydroxide catalyst composed of Ni, Fe, Cr, and Mo elements was reported. By in situ electrochemical activation, the catalyst obtained higher metal valence states and many O vacancies, providing excellent catalytic activity and corrosion resistance in overall alkaline seawater electrolysis. The floating solar seawater splitting device showed an efficiency of solar energy to hydrogen of 20.61 +/- 0.77%.
Article
Chemistry, Multidisciplinary
Hongrui Sun, Sanlong Wang, Shanshan Qi, Pengyang Wang, Renjie Li, Biao Shi, Qixing Zhang, Qian Huang, Shengzhi Xu, Ying Zhao, Xiaodan Zhang
Summary: An innovative in-situ etching (ISE) method using methanol is proposed to reduce surface defects in inorganic perovskite solar cells (IPSCs). The treatment with methanol leads to a decrease in surface defects and the passivation of grain boundary defects, resulting in a reduction in trap density and improved charge carrier extraction. The efficiency of the IPSCs is enhanced from 16.00% to 19.34% using this method.
ADVANCED FUNCTIONAL MATERIALS
(2023)
Article
Food Science & Technology
Sijie Wu, Lu Wang, Yingying Zhao, Bilian Chen, Dan Qiu, Peilong Sun, Ping Shao, Simin Feng
Summary: The strength of bio-based hydrogels can be enhanced by incorporating whey protein nanofiber (WPN) into sodium alginate (SA) hydrogels. The SA/WPN double network hydrogels showed improved rheological and textural properties through electrostatic interactions. The addition of WPN increased the storage modulus, hardness, adhesiveness, and cohesiveness of the hydrogels. Curcumin was successfully encapsulated in the SA/WPN hydrogels through various interactions and resulted in changes in the crystalline state. These findings suggest that SA/WPN double network hydrogels have potential as carriers for hydrophobic bioactive substances.
FOOD RESEARCH INTERNATIONAL
(2023)
Article
Materials Science, Multidisciplinary
Ying Zhao, Lian-Cai An, Kai Li, Yong-Ji Gong, Tian-Meng Guo, Fei-Fei Gao, Yang Lei, Quanwen Li, Wei Li, Xian-He Bu
Summary: Hybrid organic-inorganic piezoelectrics have gained attention for their fascinating performance, ease of synthesis, and mechanical flexibility. However, most reported systems contain toxic heavy metals or are unstable due to metal halide bonds. In this research, a stable zero-dimensional hybrid piezoelectric material based on an environmentally friendly anion of SCN- was synthesized. The resulting flexible composite films showed exceptional mechanical energy harvesting properties, outperforming state-of-the-art piezoelectric devices, with excellent durability and stability.
SCIENCE CHINA-MATERIALS
(2023)
