Gpr126 (Adgrg6) is expressed in cell types known to be exposed to mechanical stimuli

Myelinating Schwann Cell Polarity and Mechanically-Driven Myelin Sheath Elongation

(2018) Nicolas Tricaud   Frontiers in Cellular Neuroscience

Piezo1 is a mechanically activated ion channel and mediates pressure induced pancreatitis

(2018) Joelle M.-J. Romac et al.   Nature Communications

The oscillation of intracellular Ca2+ influx associated with the circadian expression of Piezo1 and TRPV4 in the bladder urothelium

(2018) Tatsuya Ihara et al.   Scientific Reports

A multi-ethnic meta-analysis confirms the association of rs6570507 with adolescent idiopathic scoliosis

(2018) Ikuyo Kou et al.   Scientific Reports

High Prevalence of a Hotspot of Noncoding Somatic Mutations in Intron 6 of GPR126 in Bladder Cancer

(2018) Simon Garinet et al.   MOLECULAR CANCER RESEARCH

The flow responsive transcription factor Klf2 is required for myocardial wall integrity by modulating Fgf signaling

(2018) Seyed Javad Rasouli et al.   eLife

Activation of Adhesion G Protein-coupled Receptors

(2017) Lilian M. Demberg et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TRPM7 Is Involved in Volume Regulation in Salivary Glands

(2017) J.M. Kim et al.   JOURNAL OF DENTAL RESEARCH

Genetic Variant of GPR126 Gene is Functionally Associated With Adolescent Idiopathic Scoliosis in Chinese Population

(2017) Xiaodong Qin et al.   SPINE

Effects of shear stress on endothelial cells: go with the flow

(2016) D. A. Chistiakov et al.   Acta Physiologica

Interplay between cardiac function and heart development

(2016) Laura Andrés-Delgado et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Endothelial fluid shear stress sensing in vascular health and disease

(2016) Nicolas Baeyens et al.   JOURNAL OF CLINICAL INVESTIGATION

Gpr126/Adgrg6 Has Schwann Cell Autonomous and Nonautonomous Functions in Peripheral Nerve Injury and Repair

(2016) Amit Mogha et al.   JOURNAL OF NEUROSCIENCE

The prion protein is an agonistic ligand of the G protein-coupled receptor Adgrg6

(2016) Alexander Küffer et al.   NATURE

YAP and TAZ control peripheral myelination and the expression of laminin receptors in Schwann cells

(2016) Yannick Poitelon et al.   NATURE NEUROSCIENCE

Mutations of GPR126 Are Responsible for Severe Arthrogryposis Multiplex Congenita

(2015) Gianina Ravenscroft et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Collecting Duct Intercalated Cell Function and Regulation

(2015) A. Roy et al.   Clinical Journal of the American Society of Nephrology

Establishing neural crest identity: a gene regulatory recipe

(2015) M. Simoes-Costa et al.   DEVELOPMENT

Association of GPR126 gene polymorphism with adolescent idiopathic scoliosis in Chinese populations

(2015) Ji-Feng Xu et al.   GENOMICS

Gpr126/Adgrg6deletion in cartilage models idiopathic scoliosis and pectus excavatum in mice

(2015) Courtney M. Karner et al.   HUMAN MOLECULAR GENETICS

The Adhesion GPCR GPR126 Has Distinct, Domain-Dependent Functions in Schwann Cell Development Mediated by Interaction with Laminin-211

(2015) Sarah C. Petersen et al.   NEURON

Next generation sequencing in a large cohort of patients presenting with neuromuscular disease before or at birth

(2015) Emily J. Todd et al.   Orphanet Journal of Rare Diseases

Sixteen new lung function signals identified through 1000 Genomes Project reference panel imputation

(2015) María Soler Artigas et al.   Nature Communications

Collecting Duct Principal Cell Transport Processes and Their Regulation

(2014) D. Pearce et al.   Clinical Journal of the American Society of Nephrology

Type IV collagen is an activating ligand for the adhesion G protein-coupled receptor GPR126

(2014) K. J. Paavola et al.   Science Signaling

A Tethered Agonist within the Ectodomain Activates the Adhesion G Protein-Coupled Receptors GPR126 and GPR133

(2014) Ines Liebscher et al.   Cell Reports

Analysis of Gpr126 function defines distinct mechanisms controlling the initiation and maturation of myelin

(2013) T. D. Glenn et al.   DEVELOPMENT

Semicircular canal morphogenesis in the zebrafish inner ear requires the function of gpr126 (lauscher), an adhesion class G protein-coupled receptor gene

(2013) F.-S. Geng et al.   DEVELOPMENT

Gpr126 Functions in Schwann Cells to Control Differentiation and Myelination via G-Protein Activation

(2013) A. Mogha et al.   JOURNAL OF NEUROSCIENCE

Genetic variants in GPR126 are associated with adolescent idiopathic scoliosis

(2013) Ikuyo Kou et al.   NATURE GENETICS

Organ-specific function of adhesion G protein-coupled receptor GPR126 is domain-dependent

(2013) C. Patra et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lower urinary tract development and disease

(2013) Hila Milo Rasouly et al.   Wiley Interdisciplinary Reviews-Systems Biology and Medicine

The heart endocardium is derived from vascular endothelial progenitors

(2011) M. Milgrom-Hoffman et al.   DEVELOPMENT

Gpr126 is essential for peripheral nerve development and myelination in mammals

(2011) K. R. Monk et al.   DEVELOPMENT

Characterization of the differential response of endothelial cells exposed to normal and elevated laminar shear stress

(2011) Stephen J. White et al.   JOURNAL OF CELLULAR PHYSIOLOGY

The Orphan Adhesion-GPCR GPR126 Is Required for Embryonic Development in the Mouse

(2010) Helen Waller-Evans et al.   PLoS One

Meta-analyses of genome-wide association studies identify multiple loci associated with pulmonary function

(2009) Dana B Hancock et al.   NATURE GENETICS

A G Protein-Coupled Receptor Is Essential for Schwann Cells to Initiate Myelination

(2009) K. R. Monk et al.   SCIENCE

Expression profile of the entire family of Adhesion G protein-coupled receptors in mouse and rat

(2008) Tatjana Haitina et al.   BMC NEUROSCIENCE

Anatomical Profiling of G Protein-Coupled Receptor Expression

(2008) Jean B. Regard et al.   CELL

Regulation of chondrogenesis and chondrocyte differentiation by stress

(2008) Michael J. Zuscik et al.   JOURNAL OF CLINICAL INVESTIGATION