Revisiting the classification of adhesion GPCRs

Latrophilins and Teneurins in Invertebrates: No Love for Each Other?

(2019) Torsten Schöneberg et al.   Frontiers in Neuroscience

Involvement of the Adhesion GPCRs Latrophilins in the Regulation of Insulin Release

(2019) Juliane Röthe et al.   Cell Reports

Cartography of rhodopsin-like G protein-coupled receptors across vertebrate genomes

(2019) Maiju Rinne et al.   Scientific Reports

The G protein-coupled receptors deorphanization landscape

(2018) Céline Laschet et al.   BIOCHEMICAL PHARMACOLOGY

GPR56/ADGRG1 regulates development and maintenance of peripheral myelin

(2018) Sarah D. Ackerman et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Parallel Genomic Engineering of TwoDrosophilaGenes Using OrthogonalattB/attPSites

(2018) Beatriz Blanco-Redondo et al.   G3-Genes Genomes Genetics

GPCRdb in 2018: adding GPCR structure models and ligands

(2017) Gáspár Pándy-Szekeres et al.   NUCLEIC ACIDS RESEARCH

Visualizing the GPCR Network: Classification and Evolution

(2017) Geng-Ming Hu et al.   Scientific Reports

Mechano-dependent signaling by Latrophilin/CIRL quenches cAMP in proprioceptive neurons

(2017) Nicole Scholz et al.   eLife

The constitutive activity of the adhesion GPCR GPR114/ADGRG5 is mediated by its tethered agonist

(2016) Caroline Wilde et al.   FASEB JOURNAL

MEGA7: Molecular Evolutionary Genetics Analysis Version 7.0 for Bigger Datasets

(2016) Sudhir Kumar et al.   MOLECULAR BIOLOGY AND EVOLUTION

Structural Basis for Regulation of GPR56/ADGRG1 by Its Alternatively Spliced Extracellular Domains

(2016) Gabriel S. Salzman et al.   NEURON

Structure-Based Sequence Alignment of the Transmembrane Domains of All Human GPCRs: Phylogenetic, Structural and Functional Implications

(2016) Vaclav Cvicek et al.   PLoS Computational Biology

Defining the gene repertoire and spatiotemporal expression profiles of adhesion G protein-coupled receptors in zebrafish

(2015) Breanne L Harty et al.   BMC GENOMICS

Two disparate ligand-binding sites in the human P2Y1 receptor

(2015) Dandan Zhang et al.   NATURE

The Adhesion GPCR GPR126 Has Distinct, Domain-Dependent Functions in Schwann Cell Development Mediated by Interaction with Laminin-211

(2015) Sarah C. Petersen et al.   NEURON

Structural Basis of Latrophilin-FLRT Interaction

(2015) Verity A. Jackson et al.   STRUCTURE

The Adhesion GPCR Latrophilin/CIRL Shapes Mechanosensation

(2015) Nicole Scholz et al.   Cell Reports

Oriented Cell Division in the C. elegans Embryo Is Coordinated by G-Protein Signaling Dependent on the Adhesion GPCR LAT-1

(2015) Antje Müller et al.   PLoS Genetics

Sequence, Structure and Ligand Binding Evolution of Rhodopsin-Like G Protein-Coupled Receptors: A Crystal Structure-Based Phylogenetic Analysis

(2015) Steffen Wolf et al.   PLoS One

The GPCR repertoire in the demosponge Amphimedon queenslandica: insights into the GPCR system at the early divergence of animals

(2014) Arunkumar Krishnan et al.   BMC EVOLUTIONARY BIOLOGY

Sequence-structure based phylogeny of GPCR Class A Rhodopsin receptors

(2014) Kavita Kumari Kakarala et al.   MOLECULAR PHYLOGENETICS AND EVOLUTION

Agonist-bound structure of the human P2Y12 receptor

(2014) Jin Zhang et al.   NATURE

Structure of the human P2Y12 receptor in complex with an antithrombotic drug

(2014) Kaihua Zhang et al.   NATURE

A Tethered Agonist within the Ectodomain Activates the Adhesion G Protein-Coupled Receptors GPR126 and GPR133

(2014) Ines Liebscher et al.   Cell Reports

Remarkable similarities between the hemichordate (Saccoglossus kowalevskii) and vertebrate GPCR repertoire

(2013) Arunkumar Krishnan et al.   GENE

Latrophilins Function as Heterophilic Cell-adhesion Molecules by Binding to Teneurins

(2013) Antony A. Boucard et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A novel evolutionarily conserved domain of cell-adhesion GPCRs mediates autoproteolysis

(2012) Demet Araç et al.   EMBO JOURNAL

High Affinity Neurexin Binding to Cell Adhesion G-protein-coupled Receptor CIRL1/Latrophilin-1 Produces an Intercellular Adhesion Complex

(2012) Antony A. Boucard et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The GPS Motif Is a Molecular Switch for Bimodal Activities of Adhesion Class G Protein-Coupled Receptors

(2012) Simone Prömel et al.   Cell Reports

An improved classification of G-protein-coupled receptors using sequence-derived features

(2010) Zhen-Ling Peng et al.   BMC BIOINFORMATICS

7TMRmine: a Web server for hierarchical mining of 7TMR proteins

(2009) Guoqing Lu et al.   BMC GENOMICS

Latrophilin Signaling Links Anterior-Posterior Tissue Polarity and Oriented Cell Divisions in the C. elegans Embryo

(2009) Tobias Langenhan et al.   DEVELOPMENTAL CELL

The amphioxus (Branchiostoma floridae) genome contains a highly diversified set of G protein-coupled receptors

(2008) Karl JV Nordström et al.   BMC EVOLUTIONARY BIOLOGY

Expression profile of the entire family of Adhesion G protein-coupled receptors in mouse and rat

(2008) Tatjana Haitina et al.   BMC NEUROSCIENCE

The Secretin GPCRs Descended from the Family of Adhesion GPCRs

(2008) K. J. V. Nordstrom et al.   MOLECULAR BIOLOGY AND EVOLUTION

Structural diversity of G protein-coupled receptors and significance for drug discovery

(2008) Malin C. Lagerström et al.   NATURE REVIEWS DRUG DISCOVERY

Orphan GPCR research

(2007) S Chung et al.   BRITISH JOURNAL OF PHARMACOLOGY