Epileptic seizures and oxidative stress in a mouse model over-expressing spermine oxidase

Glutamate Excitotoxicity Linked to Spermine Oxidase Overexpression

(2018) Stefano Pietropaoli et al.   MOLECULAR NEUROBIOLOGY

Adaptive responses of heart and skeletal muscle to spermine oxidase overexpression: Evaluation of a new transgenic mouse model

(2017) Roberta Ceci et al.   FREE RADICAL BIOLOGY AND MEDICINE

Activation of endoplasmic reticulum stress response by enhanced polyamine catabolism is important in the mediation of cisplatin-induced acute kidney injury

(2017) Kamyar Zahedi et al.   PLoS One

Stability of spermine oxidase to thermal and chemical denaturation: comparison with bovine serum amine oxidase

(2016) Manuela Cervelli et al.   AMINO ACIDS

HIV-Tat Induces the Nrf2/ARE Pathway through NMDA Receptor-Elicited Spermine Oxidase Activation in Human Neuroblastoma Cells

(2016) Roberta Mastrantonio et al.   PLoS One

Overview of Nrf2 as Therapeutic Target in Epilepsy

(2015) Liliana Carmona-Aparicio et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Astrocyte-Dependent Vulnerability to Excitotoxicity in Spermine Oxidase-Overexpressing Mouse

(2015) Chiara Cervetto et al.   NEUROMOLECULAR MEDICINE

Anticonvulsant effect of neural regeneration peptide 2945 on pentylenetetrazol-induced seizures in rats

(2015) Azadeh Sajadian et al.   NEUROPEPTIDES

Seizure-Induced Oxidative Stress in Temporal Lobe Epilepsy

(2015) Sreekanth Puttachary et al.   Biomed Research International

Polyamines metabolism and breast cancer: state of the art and perspectives

(2014) Manuela Cervelli et al.   BREAST CANCER RESEARCH AND TREATMENT

Inflammation, carcinogenesis and neurodegeneration studies in transgenic animal models for polyamine research

(2013) Manuela Cervelli et al.   AMINO ACIDS

Spermine metabolism and radiation-derived reactive oxygen species for future therapeutic implications in cancer: an additive or adaptive response

(2013) Roberto Amendola et al.   AMINO ACIDS

Bilirubin mediated oxidative stress involves antioxidant response activation via Nrf2 pathway

(2013) Mohammed Qaisiya et al.   CELLULAR SIGNALLING

A role for spermine oxidase as a mediator of reactive oxygen species production in HIV-Tat-induced neuronal toxicity

(2013) Caterina Capone et al.   FREE RADICAL BIOLOGY AND MEDICINE

Reactive oxygen species spermine metabolites generated from amine oxidases and radiation represent a therapeutic gain in cancer treatments

(2013) ROBERTO AMENDOLA et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Structure–Function Relationships in the Evolutionary Framework of Spermine Oxidase

(2013) Manuela Cervelli et al.   JOURNAL OF MOLECULAR EVOLUTION

Glutamate and tumor-associated epilepsy: Glial cell dysfunction in the peritumoral environment

(2013) Susan C. Buckingham et al.   NEUROCHEMISTRY INTERNATIONAL

A New Transgenic Mouse Model for Studying the Neurotoxicity of Spermine Oxidase Dosage in the Response to Excitotoxic Injury

(2013) Manuela Cervelli et al.   PLoS One

The Cystine/Glutamate Antiporter System xc− in Health and Disease: From Molecular Mechanisms to Novel Therapeutic Opportunities

(2012) Jan Lewerenz et al.   ANTIOXIDANTS & REDOX SIGNALING

Molecular evolution of the polyamine oxidase gene family in Metazoa

(2012) Fabio Polticelli et al.   BMC EVOLUTIONARY BIOLOGY

Decreased GABABR expression and increased neuronal cell death in developing rat brain after PTZ-induced seizure

(2012) Muhammad Imran Naseer et al.   NEUROLOGICAL SCIENCES

Spermine oxidase: ten years after

(2011) Manuela Cervelli et al.   AMINO ACIDS

System xc- cystine/glutamate antiporter: an update on molecular pharmacology and roles within the CNS

(2011) Richard J Bridges et al.   BRITISH JOURNAL OF PHARMACOLOGY

Spermine Oxidase Mediates the Gastric Cancer Risk Associated With Helicobacter pylori CagA

(2011) Rupesh Chaturvedi et al.   GASTROENTEROLOGY

Glutamate release by primary brain tumors induces epileptic activity

(2011) Susan C Buckingham et al.   NATURE MEDICINE

Probing mammalian spermine oxidase enzyme–substrate complex through molecular modeling, site-directed mutagenesis and biochemical characterization

(2010) Paraskevi Tavladoraki et al.   AMINO ACIDS

Spermine oxidase (SMO) activity in breast tumor tissues and biochemical analysis of the anticancer spermine analogues BENSpm and CPENSpm

(2010) Manuela Cervelli et al.   BMC CANCER

Glutamate and the biology of gliomas

(2010) John de Groot et al.   GLIA

Polyamine catabolism and disease

(2009) Robert A. Casero et al.   BIOCHEMICAL JOURNAL

Spermine Metabolism and Anticancer Therapy

(2009) R. Amendola et al.   CURRENT CANCER DRUG TARGETS

Polyamine Catabolism Is Enhanced after Traumatic Brain Injury

(2009) Kamyar Zahedi et al.   JOURNAL OF NEUROTRAUMA

Role of Glutamate and GABA Transporters in Development of Pentylenetetrazol-Kindling

(2009) Taku Doi et al.   NEUROCHEMICAL RESEARCH

A revised Racine's scale for PTZ-induced seizures in rats

(2009) Annika Lüttjohann et al.   PHYSIOLOGY & BEHAVIOR

Modern management of epilepsy: A practical approach

(2008) Christian E. Elger et al.   EPILEPSY & BEHAVIOR

Increased spermine oxidase (SMO) activity as a novel differentiation marker of myogenic C2C12 cells

(2008) Manuela Cervelli et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Increased spermine oxidase expression in human prostate cancer and prostatic intraepithelial neoplasia tissues

(2008) Andrew C. Goodwin et al.   PROSTATE