N6-Methyladenosine (m6A): A Promising New Molecular Target in Acute Myeloid Leukemia
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Title
N6-Methyladenosine (m6A): A Promising New Molecular Target in Acute Myeloid Leukemia
Authors
Keywords
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Journal
Frontiers in Oncology
Volume 9, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2019-04-09
DOI
10.3389/fonc.2019.00251
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Note: Only part of the references are listed.- R-2HG Exhibits Anti-tumor Activity by Targeting FTO/m 6 A/MYC/CEBPA Signaling
- (2018) Rui Su et al. CELL
- Mettl3–Mettl14 methyltransferase complex regulates the quiescence of adult hematopoietic stem cells
- (2018) Qi Jason Yao et al. CELL RESEARCH
- METTL14 Inhibits Hematopoietic Stem/Progenitor Differentiation and Promotes Leukemogenesis via mRNA m 6 A Modification
- (2018) Hengyou Weng et al. Cell Stem Cell
- MALAT1: a druggable long non-coding RNA for targeted anti-cancer approaches
- (2018) Nicola Amodio et al. Journal of Hematology & Oncology
- Recognition of RNA N6-methyladenosine by IGF2BP proteins enhances mRNA stability and translation
- (2018) Huilin Huang et al. NATURE CELL BIOLOGY
- RNA-modifying proteins as anticancer drug targets
- (2018) P. Ann Boriack-Sjodin et al. NATURE REVIEWS DRUG DISCOVERY
- Reading m 6 A in the Transcriptome: m 6 A-Binding Proteins
- (2018) Deepak P. Patil et al. TRENDS IN CELL BIOLOGY
- Solution structure of the RNA recognition domain of METTL3-METTL14 N6-methyladenosine methyltransferase
- (2018) Jinbo Huang et al. Protein & Cell
- N 6 -methyladenosine modification: a novel pharmacological target for anti-cancer drug development
- (2018) Yi Niu et al. Acta Pharmaceutica Sinica B
- Loss of YTHDF2-mediated m6A-dependent mRNA clearance facilitates hematopoietic stem cell regeneration
- (2018) Hu Wang et al. CELL RESEARCH
- N6-Methyladenosine Role in Acute Myeloid Leukaemia
- (2018) Zaira Ianniello et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- The Biogenesis, Functions, and Challenges of Circular RNAs
- (2018) Xiang Li et al. MOLECULAR CELL
- Differential m6A, m6Am, and m1A Demethylation Mediated by FTO in the Cell Nucleus and Cytoplasm
- (2018) Jiangbo Wei et al. MOLECULAR CELL
- mRNA circularization by METTL3–eIF3h enhances translation and promotes oncogenesis
- (2018) Junho Choe et al. NATURE
- METTL3 regulates WTAP protein homeostasis
- (2018) Melissa Sorci et al. Cell Death & Disease
- Refined RIP-seq protocol for epitranscriptome analysis with low input materials
- (2018) Yong Zeng et al. PLOS BIOLOGY
- Mechanistic insights into m6A RNA enzymes
- (2018) Tina Lence et al. Biochimica et Biophysica Acta-Gene Regulatory Mechanisms
- Cap-specific, terminal N6-methylation by a mammalian m6Am methyltransferase
- (2018) Hanxiao Sun et al. CELL RESEARCH
- Cap-specific terminal N6-methylation of RNA by an RNA polymerase II–associated methyltransferase
- (2018) Shinichiro Akichika et al. SCIENCE
- A peptide encoded by circular form of LINC-PINT suppresses oncogenic transcriptional elongation in glioblastoma
- (2018) Maolei Zhang et al. Nature Communications
- Rational Design of Bisubstrate-Type Analogues as Inhibitors of DNA Methyltransferases in Cancer Cells
- (2017) Ludovic Halby et al. JOURNAL OF MEDICINAL CHEMISTRY
- m6A modulates haematopoietic stem and progenitor cell specification
- (2017) Chunxia Zhang et al. NATURE
- Promoter-bound METTL3 maintains myeloid leukaemia by m6A-dependent translation control
- (2017) Isaia Barbieri et al. NATURE
- The N6-methyladenosine (m6A)-forming enzyme METTL3 controls myeloid differentiation of normal hematopoietic and leukemia cells
- (2017) Ly P Vu et al. NATURE MEDICINE
- N6-methyladenosine (m6A) recruits and repels proteins to regulate mRNA homeostasis
- (2017) Raghu R Edupuganti et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- N 6-methyladenosine alters RNA structure to regulate binding of a low-complexity protein
- (2017) Nian Liu et al. NUCLEIC ACIDS RESEARCH
- N6-methyladenosine (m6A) recruits and repels proteins to regulate mRNA homeostasis
- (2017) Raghu R Edupuganti et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Inhibition of EZH2 triggers the tumor suppressive miR-29b network in multiple myeloma
- (2017) Maria Angelica Stamato et al. Oncotarget
- S -Adenosylmethionine Synthesis Is Regulated by Selective N 6 -Adenosine Methylation and mRNA Degradation Involving METTL16 and YTHDC1
- (2017) Hiroki Shima et al. Cell Reports
- Genome-Wide Maps of m6A circRNAs Identify Widespread and Cell-Type-Specific Methylation Patterns that Are Distinct from mRNAs
- (2017) Chan Zhou et al. Cell Reports
- Computational methods in drug discovery
- (2016) Sumudu P Leelananda et al. Beilstein Journal of Organic Chemistry
- Oncogenic Role of Fusion-circRNAs Derived from Cancer-Associated Chromosomal Translocations
- (2016) Jlenia Guarnerio et al. CELL
- RBM15 Functions in Blood Diseases
- (2016) Mengyu Hu et al. CURRENT CANCER DRUG TARGETS
- Structural Basis for Cooperative Function of Mettl3 and Mettl14 Methyltransferases
- (2016) Ping Wang et al. MOLECULAR CELL
- The m 6 A Methyltransferase METTL3 Promotes Translation in Human Cancer Cells
- (2016) Shuibin Lin et al. MOLECULAR CELL
- Structural basis of N6-adenosine methylation by the METTL3–METTL14 complex
- (2016) Xiang Wang et al. NATURE
- m6A RNA methylation promotes XIST-mediated transcriptional repression
- (2016) Deepak P. Patil et al. NATURE
- Post-transcriptional gene regulation by mRNA modifications
- (2016) Boxuan Simen Zhao et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- MTAPdeletion confers enhanced dependency on the PRMT5 arginine methyltransferase in cancer cells
- (2016) Gregory V. Kryukov et al. SCIENCE
- Discovery of Novel Dot1L Inhibitors through a Structure-Based Fragmentation Approach
- (2016) Chao Chen et al. ACS Medicinal Chemistry Letters
- Long noncoding RNA MALAT1 promotes malignant development of esophageal squamous cell carcinoma by targeting β-catenin via Ezh2
- (2016) Wei Wang et al. Oncotarget
- Long non-coding RNA MALAT1 acts as a competing endogenous RNA to promote malignant melanoma growth and metastasis by sponging miR-22
- (2016) Wenkang Luan et al. Oncotarget
- Structural insights into the molecular mechanism of the m6A writer complex
- (2016) Paweł Śledź et al. eLife
- N6-methyladenosine Modulates Messenger RNA Translation Efficiency
- (2015) Xiao Wang et al. CELL
- Structural imprints in vivo decode RNA regulatory mechanisms
- (2015) Robert C. Spitale et al. NATURE
- N6-methyladenosine-dependent RNA structural switches regulate RNA–protein interactions
- (2015) Nian Liu et al. NATURE
- A selective inhibitor of PRMT5 with in vivo and in vitro potency in MCL models
- (2015) Elayne Chan-Penebre et al. Nature Chemical Biology
- Single-nucleotide-resolution mapping of m6A and m6Am throughout the transcriptome
- (2015) Bastian Linder et al. NATURE METHODS
- Structural basis of asymmetric DNA methylation and ATP-triggered long-range diffusion by EcoP15I
- (2015) Yogesh K. Gupta et al. Nature Communications
- Cross-talk between PRMT1-mediated methylation and ubiquitylation on RBM15 controls RNA splicing
- (2015) Li Zhang et al. eLife
- Correlation of circular RNA abundance with proliferation – exemplified with colorectal and ovarian cancer, idiopathic lung fibrosis and normal human tissues
- (2015) Anna Bachmayr-Heyda et al. Scientific Reports
- Isolated trisomy 13 defines a homogeneous AML subgroup with high frequency of mutations in spliceosome genes and poor prognosis
- (2014) T. Herold et al. BLOOD
- Mammalian WTAP is a regulatory subunit of the RNA N6-methyladenosine methyltransferase
- (2014) Xiao-Li Ping et al. CELL RESEARCH
- m6A RNA Modification Controls Cell Fate Transition in Mammalian Embryonic Stem Cells
- (2014) Pedro J. Batista et al. Cell Stem Cell
- Characteristics of hematopoietic stem cells of umbilical cord blood
- (2014) Anna Hordyjewska et al. CYTOTECHNOLOGY
- WTAP is a novel oncogenic protein in acute myeloid leukemia
- (2014) H Bansal et al. LEUKEMIA
- Comparison of promoter DNA methylation and expression levels of genes encoding CCAAT/enhancer binding proteins in AML patients
- (2014) Ewa Musialik et al. LEUKEMIA RESEARCH
- Targeting MLL1 H3K4 Methyltransferase Activity in Mixed-Lineage Leukemia
- (2014) Fang Cao et al. MOLECULAR CELL
- Xist RNA Is a Potent Suppressor of Hematologic Cancer in Mice
- (2013) Eda Yildirim et al. CELL
- Identification of Wilms' Tumor 1-associating Protein Complex and Its Role in Alternative Splicing and the Cell Cycle
- (2013) Keiko Horiuchi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- N6-methyladenosine-dependent regulation of messenger RNA stability
- (2013) Xiao Wang et al. NATURE
- A METTL3–METTL14 complex mediates mammalian nuclear RNA N6-adenosine methylation
- (2013) Jianzhao Liu et al. Nature Chemical Biology
- Comprehensive Analysis of mRNA Methylation Reveals Enrichment in 3′ UTRs and near Stop Codons
- (2012) Kate D. Meyer et al. CELL
- Biological effects of decreasingRBM15on chronic myelogenous leukemia cells
- (2012) Yuxia Yang et al. LEUKEMIA & LYMPHOMA
- ALKBH5 Is a Mammalian RNA Demethylase that Impacts RNA Metabolism and Mouse Fertility
- (2012) Guanqun Zheng et al. MOLECULAR CELL
- Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq
- (2012) Dan Dominissini et al. NATURE
- ncRNA- and Pc2 Methylation-Dependent Gene Relocation between Nuclear Structures Mediates Gene Activation Programs
- (2011) Liuqing Yang et al. CELL
- Chemogenetic Analysis of Human Protein Methyltransferases
- (2011) Victoria M. Richon et al. Chemical Biology & Drug Design
- Structural Chemistry of the Histone Methyltransferases Cofactor Binding Site
- (2011) Valérie Campagna-Slater et al. Journal of Chemical Information and Modeling
- N6-Methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO
- (2011) Guifang Jia et al. Nature Chemical Biology
- The Nuclear-Retained Noncoding RNA MALAT1 Regulates Alternative Splicing by Modulating SR Splicing Factor Phosphorylation
- (2010) Vidisha Tripathi et al. MOLECULAR CELL
- c-Myc is a target of RNA-binding motif protein 15 in the regulation of adult hematopoietic stem cell and megakaryocyte development
- (2009) C. Niu et al. BLOOD
- The OTT-MAL fusion oncogene activates RBPJ-mediated transcription and induces acute megakaryoblastic leukemia in a knockin mouse model
- (2009) Thomas Mercher et al. JOURNAL OF CLINICAL INVESTIGATION
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