NLRX1 Enhances Glutamate Uptake and Inhibits Glutamate Release by Astrocytes

Astrocytes Maintain Glutamate Homeostasis in the CNS by Controlling the Balance between Glutamate Uptake and Release

(2019) Shaimaa Mahmoud et al.   Cells

NLRX1 regulates TNF-α-induced mitochondria-lysosomal crosstalk to maintain the invasive and metastatic potential of breast cancer cells

(2019) Kritarth Singh et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

NLRX1 alleviates lipopolysaccharide-induced apoptosis and inflammation in chondrocytes by suppressing the activation of NF-κB signaling

(2019) Ding Ma et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

NLRX1 Modulates Immunometabolic Mechanisms Controlling the Host–Gut Microbiota Interactions during Inflammatory Bowel Disease

(2018) Andrew Leber et al.   Frontiers in Immunology

NLR-Dependent Regulation of Inflammation in Multiple Sclerosis

(2018) Marjan Gharagozloo et al.   Frontiers in Immunology

The mitochondrial Nod-like receptor NLRX1 modifies apoptosis through SARM1

(2018) Samuel A. Killackey et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

The Dual Immunoregulatory function of Nlrp12 in T Cell-Mediated Immune Response: Lessons from Experimental Autoimmune Encephalomyelitis

(2018) Marjan Gharagozloo et al.   Cells

NLRX1 Negatively Regulates Group A Streptococcus Invasion and Autophagy Induction by Interacting With the Beclin 1–UVRAG Complex

(2018) Chihiro Aikawa et al.   Frontiers in Cellular and Infection Microbiology

NLRX1 Facilitates Histoplasma capsulatum-Induced LC3-Associated Phagocytosis for Cytokine Production in Macrophages

(2018) Juin-Hua Huang et al.   Frontiers in Immunology

NLRX1 dampens oxidative stress and apoptosis in tissue injury via control of mitochondrial activity

(2017) Geurt Stokman et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Loss of NLRX1 Exacerbates Neural Tissue Damage and NF-κB Signaling following Brain Injury

(2017) Michelle H. Theus et al.   JOURNAL OF IMMUNOLOGY

IL-17 signalling in astrocytes promotes glutamate excitotoxicity: Indications for the link between inflammatory and neurodegenerative events in multiple sclerosis

(2017) Milos Kostic et al.   Multiple Sclerosis and Related Disorders

NLRX1 Acts as an Epithelial-Intrinsic Tumor Suppressor through the Modulation of TNF-Mediated Proliferation

(2016) Ivan Tattoli et al.   Cell Reports

Thrombin decreases expression of the glutamate transporter GLAST and inhibits glutamate uptake in primary cortical astrocytes via the Rho kinase pathway

(2015) Chunshu Piao et al.   EXPERIMENTAL NEUROLOGY

The nod-like receptor, Nlrp12, plays an anti-inflammatory role in experimental autoimmune encephalomyelitis

(2015) Marjan Gharagozloo et al.   Journal of Neuroinflammation

The Mitochondrial Protein NLRX1 Controls the Balance between Extrinsic and Intrinsic Apoptosis

(2014) Fraser Soares et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

NLRX1 prevents mitochondrial induced apoptosis and enhances macrophage antiviral immunity by interacting with influenza virus PB1-F2 protein

(2014) J. Jaworska et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nlrx1 regulates neuronal cell death

(2014) Emilie Imbeault et al.   Molecular Brain

The Nucleotide-binding Leucine-rich Repeat (NLR) Family Member NLRX1 Mediates Protection against Experimental Autoimmune Encephalomyelitis and Represses Macrophage/Microglia-induced Inflammation

(2013) Timothy K. Eitas et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

FACS analysis of neuronal–glial interactions in the nucleus accumbens following morphine administration

(2013) Jaclyn M. Schwarz et al.   PSYCHOPHARMACOLOGY

Glutamate Pays Its Own Way in Astrocytes

(2013) Mary C. McKenna   Frontiers in Endocrinology

bFGF-mediated redox activation of the PI3K/Akt pathway in retinal photoreceptor cells

(2011) Stephen M. J. Farrell et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

NLRX1 Protein Attenuates Inflammatory Responses to Infection by Interfering with the RIG-I-MAVS and TRAF6-NF-κB Signaling Pathways

(2011) Irving C. Allen et al.   IMMUNITY

Molecular and cellular mechanisms of excitotoxic neuronal death

(2010) Yan Wang et al.   APOPTOSIS

Regional variation in mitochondrial DNA copy number in mouse brain

(2010) Satoshi Fuke et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Neurotransmitter transporters expressed in glial cells as regulators of synapse function

(2010) Volker Eulenburg et al.   BRAIN RESEARCH REVIEWS

Do astrocytes really exocytose neurotransmitters?

(2010) Nicola B. Hamilton et al.   NATURE REVIEWS NEUROSCIENCE

Astrocytes: biology and pathology

(2009) Michael V. Sofroniew et al.   ACTA NEUROPATHOLOGICA

Gliotransmission: Exocytotic release from astrocytes

(2009) Vladimir Parpura et al.   BRAIN RESEARCH REVIEWS

The systemic inflammatory response after spinal cord injury damages lungs and kidneys

(2008) Denis Gris et al.   EXPERIMENTAL NEUROLOGY

Glutamate forward and reverse transport: From molecular mechanism to transporter-mediated release after ischemia

(2008) Christof Grewer et al.   IUBMB LIFE

Mitochondria Modulate Ca2+-Dependent Glutamate Release from Rat Cortical Astrocytes

(2008) R. C. Reyes et al.   JOURNAL OF NEUROSCIENCE

NLRX1 is a regulator of mitochondrial antiviral immunity

(2008) Chris B. Moore et al.   NATURE

Analyzing real-time PCR data by the comparative CT method

(2008) Thomas D Schmittgen et al.   Nature Protocols

Mechanisms of glutamate release from astrocytes

(2007) Erik B. Malarkey et al.   NEUROCHEMISTRY INTERNATIONAL