Major Histocompatibility Complex (MHC) Genes and Disease Resistance in Fish

Whole genome duplications have provided teleosts with many roads to peptide loaded MHC class I molecules

(2018) Unni Grimholt   BMC EVOLUTIONARY BIOLOGY

Genomic architecture of haddock (Melanogrammus aeglefinus) shows expansions of innate immune genes and short tandem repeats

(2018) Ole K. Tørresen et al.   BMC GENOMICS

Tapasin's protein interactions in the rainbow trout peptide-loading complex

(2018) Lital Sever et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Structural insights into the evolution feature of a bony fish CD8αα homodimer

(2018) Junya Wang et al.   MOLECULAR IMMUNOLOGY

Accumulating evidence suggests that men do not find body odours of human leucocyte antigen-dissimilar women more attractive

(2018) Janek S. Lobmaier et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Generalists and Specialists: A New View of How MHC Class I Molecules Fight Infectious Pathogens

(2018) Jim Kaufman   TRENDS IN IMMUNOLOGY

Genetics of antigen processing and presentation

(2018) Adrian Kelly et al.   IMMUNOGENETICS

The immunoproteasome and thymoproteasome: functions, evolution and human disease

(2018) Shigeo Murata et al.   NATURE IMMUNOLOGY

Ancient features of the MHC class II presentation pathway, and a model for the possible origin of MHC molecules

(2018) Johannes M. Dijkstra et al.   IMMUNOGENETICS

Sequences of 95 humanMHChaplotypes reveal extreme coding variation in genes other than highly polymorphicHLA class IandII

(2017) Paul J. Norman et al.   GENOME RESEARCH

MHC and adaptive immunity in teleost fishes

(2017) Anthony B. Wilson   IMMUNOGENETICS

Conservation of sequence motifs suggests that the nonclassical MHC class I lineages CD1/PROCR and UT were established before the emergence of tetrapod species

(2017) Johannes M. Dijkstra et al.   IMMUNOGENETICS

Introduction: MHC/KIR and governance of specificity

(2017) Adrian Kelly et al.   IMMUNOGENETICS

The immunogenetics of neurological disease

(2017) Maneesh K. Misra et al.   IMMUNOLOGY

The Structure of the MHC Class I Molecule of Bony Fishes Provides Insights into the Conserved Nature of the Antigen-Presenting System

(2017) Zhaosan Chen et al.   JOURNAL OF IMMUNOLOGY

Identification of Quantitative Trait Loci for Resistance to RSIVD in Red Sea Bream (Pagrus major)

(2017) Eitaro Sawayama et al.   MARINE BIOTECHNOLOGY

Structure of the human MHC-I peptide-loading complex

(2017) Andreas Blees et al.   NATURE

Similar Genetic Architecture with Shared and Unique Quantitative Trait Loci for Bacterial Cold Water Disease Resistance in Two Rainbow Trout Breeding Populations

(2017) Roger L. Vallejo et al.   Frontiers in Genetics

Gene expression comparison of resistant and susceptible Atlantic salmon fry challenged with Infectious Pancreatic Necrosis virus reveals a marked contrast in immune response

(2016) Diego Robledo et al.   BMC GENOMICS

The role of MHC class Ib-restricted T cells during infection

(2016) Courtney K. Anderson et al.   IMMUNOGENETICS

Novel Teleost CD4-Bearing Cell Populations Provide Insights into the Evolutionary Origins and Primordial Roles of CD4+Lymphocytes and CD4+Macrophages

(2016) Fumio Takizawa et al.   JOURNAL OF IMMUNOLOGY

The Atlantic salmon genome provides insights into rediploidization

(2016) Sigbjørn Lien et al.   NATURE

Widespread transmission of independent cancer lineages within multiple bivalve species

(2016) Michael J. Metzger et al.   NATURE

Evolution of the immune system influences speciation rates in teleost fishes

(2016) Martin Malmstrøm et al.   NATURE GENETICS

IPD-MHC 2.0: an improved inter-species database for the study of the major histocompatibility complex

(2016) Giuseppe Maccari et al.   NUCLEIC ACIDS RESEARCH

Alternative haplotypes of antigen processing genes in zebrafish diverged early in vertebrate evolution

(2016) Sean C. McConnell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Aggressive Behavior, Brain Size and Domestication in Clonal Rainbow Trout Lines

(2015) Janet M. Campbell et al.   BEHAVIOR GENETICS

A comprehensive analysis of teleost MHC class I sequences

(2015) Unni Grimholt et al.   BMC EVOLUTIONARY BIOLOGY

Mapping and validation of a major QTL affecting resistance to pancreas disease (salmonid alphavirus) in Atlantic salmon (Salmo salar)

(2015) S Gonen et al.   HEREDITY

A nonclassical MHC class I U lineage locus in zebrafish with a null haplotypic variant

(2015) Hayley Dirscherl et al.   IMMUNOGENETICS

Identification of Single-Nucleotide Polymorphism Markers Associated with Cortisol Response to Crowding in Rainbow Trout

(2015) Sixin Liu et al.   MARINE BIOTECHNOLOGY

The Src tyrosine kinase Lck binds to CD2, CD4-1, and CD4-2 T cell co-receptors in channel catfish, Ictalurus punctatus

(2015) Erin B. Taylor et al.   MOLECULAR IMMUNOLOGY

Surface expression, peptide repertoire, and thermostability of chicken class I molecules correlate with peptide transporter specificity

(2015) Clive A. Tregaskes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genome Assembly Improvement and Mapping Convergently Evolved Skeletal Traits in Sticklebacks with Genotyping-by-Sequencing

(2015) Andrew M. Glazer et al.   G3-Genes Genomes Genetics

Identification of single nucleotide polymorphism markers associated with bacterial cold water disease resistance and spleen size in rainbow trout

(2015) Sixin Liu et al.   Frontiers in Genetics

Detection and Validation of QTL Affecting Bacterial Cold Water Disease Resistance in Rainbow Trout Using Restriction-Site Associated DNA Sequencing

(2015) Yniv Palti et al.   PLoS One

Of volatiles and peptides: in search for MHC-dependent olfactory signals in social communication

(2014) Peter Overath et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Developmental Sculpting of Intracortical Circuits by MHC Class I H2-Db and H2-Kb

(2014) Jaimie D. Adelson et al.   CEREBRAL CORTEX

The MHC class I genes of zebrafish

(2014) Hayley Dirscherl et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Evolution of dimorphisms of the proteasome subunit beta type 8 gene (PSMB8) in basal ray-finned fish

(2014) Megumi Noro et al.   IMMUNOGENETICS

Xenotransplantation: immunological hurdles and progress toward tolerance

(2014) Adam Griesemer et al.   IMMUNOLOGICAL REVIEWS

Molecular characterization and expressional affirmation of the beta proteasome subunit cluster in rock bream immune defense

(2014) Saranya Revathy Kasthuri et al.   MOLECULAR BIOLOGY REPORTS

Elephant shark genome provides unique insights into gnathostome evolution

(2014) Byrappa Venkatesh et al.   NATURE

TH2 and Treg candidate genes in elephant shark

(2014) Johannes M. Dijkstra   NATURE

Synapse elimination and learning rules co-regulated by MHC class I H2-Db

(2014) Hanmi Lee et al.   NATURE

The rainbow trout genome provides novel insights into evolution after whole-genome duplication in vertebrates

(2014) Camille Berthelot et al.   Nature Communications

Major Histocompatibility Complex Genomics and Human Disease

(2013) John Trowsdale et al.   Annual Review of Genomics and Human Genetics

The Adaptable Major Histocompatibility Complex (MHC) Fold: Structure and Function of Nonclassical and MHC Class I–Like Molecules

(2013) Erin J. Adams et al.   Annual Review of Immunology

Absence of major histocompatibility complex class II mediated immunity in pipefish, Syngnathus typhle: evidence from deep transcriptome sequencing

(2013) D. Haase et al.   Biology Letters

Comprehensive analysis of MHC class II genes in teleost fish genomes reveals dispensability of the peptide-loading DM system in a large part of vertebrates

(2013) Johannes M Dijkstra et al.   BMC EVOLUTIONARY BIOLOGY

Multiple divergent haplotypes express completely distinct sets of class I MHC genes in zebrafish

(2013) Sean C. McConnell et al.   IMMUNOGENETICS

Characterization of the Z lineage Major histocompatability complex class I genes in zebrafish

(2013) Hayley Dirscherl et al.   IMMUNOGENETICS

Comprehensive analysis of medaka major histocompatibility complex (MHC) class II genes: Implications for evolution in teleosts

(2013) Hidemi P. Bannai et al.   IMMUNOGENETICS

A Mechanistic Basis for the Co-evolution of Chicken Tapasin and Major Histocompatibility Complex Class I (MHC I) Proteins

(2013) Andy van Hateren et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Detection of QTL in Rainbow Trout Affecting Survival When Challenged with Flavobacterium psychrophilum

(2013) Roger L. Vallejo et al.   MARINE BIOTECHNOLOGY

Resistance to a Rhabdovirus (VHSV) in Rainbow Trout: Identification of a Major QTL Related to Innate Mechanisms

(2013) Eloi R. Verrier et al.   PLoS One

Assessment of Genetic Correlation between Bacterial Cold Water Disease Resistance and Spleen Index in a Domesticated Population of Rainbow Trout: Identification of QTL on Chromosome Omy19

(2013) Gregory D. Wiens et al.   PLoS One

Mapping rainbow trout immune genes involved in inflammation reveals conserved blocks of immune genes in teleosts

(2012) R. B. Phillips et al.   ANIMAL GENETICS

Identification of anti-viral cytotoxic effector cells in the ginbuna crucian carp, Carassius auratus langsdorfii

(2012) Tomonori Somamoto et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

HIV and HLA Class I: An Evolving Relationship

(2012) Philip J.R. Goulder et al.   IMMUNITY

Conformational variation in structures of classical and non-classical MHCII proteins and functional implications

(2012) Corrie A. Painter et al.   IMMUNOLOGICAL REVIEWS

Long-Lived Dichotomous Lineages of the Proteasome Subunit Beta Type 8 (PSMB8) Gene Surviving More than 500 Million Years as Alleles or Paralogs

(2012) Kentaro Tsukamoto et al.   MOLECULAR BIOLOGY AND EVOLUTION

Major histocompatibility complex class I proteins in brain development and plasticity

(2012) Bradford M. Elmer et al.   TRENDS IN NEUROSCIENCES

A first generation integrated map of the rainbow trout genome

(2011) Yniv Palti et al.   BMC GENOMICS

The expression of CD8α discriminates distinct T cell subsets in teleost fish

(2011) Fumio Takizawa et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Shark class II invariant chain reveals ancient conserved relationships with cathepsins and MHC class II

(2011) Michael F. Criscitiello et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Cytotoxic CD8α+ leucocytes have heterogeneous features in antigen recognition and class I MHC restriction in grouper

(2011) Yun-Tsan Chang et al.   FISH & SHELLFISH IMMUNOLOGY

Primordial Linkage of  2-Microglobulin to the MHC

(2011) Y. Ohta et al.   JOURNAL OF IMMUNOLOGY

Retained Orthologous Relationships of the MHC Class I Genes during Euteleost Evolution

(2011) Mayumi I. Nonaka et al.   MOLECULAR BIOLOGY AND EVOLUTION

The genome sequence of Atlantic cod reveals a unique immune system

(2011) Bastiaan Star et al.   NATURE

The dominantly expressed class I molecule of the chicken MHC is explained by coevolution with the polymorphic peptide transporter (TAP) genes

(2011) B. A. Walker et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Impacts of the Cretaceous Terrestrial Revolution and KPg Extinction on Mammal Diversification

(2011) R. W. Meredith et al.   SCIENCE

Description of an elasmobranch TCR coreceptor: CD8α from Rhinobatos productus

(2010) John D. Hansen et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

A major effect quantitative trait locus for whirling disease resistance identified in rainbow trout (Oncorhynchus mykiss)

(2010) M R Baerwald et al.   HEREDITY

Evolutionary analysis of two classical MHC class I loci of the medaka fish, Oryzias latipes: haplotype-specific genomic diversity, locus-specific polymorphisms, and interlocus homogenization

(2010) Mayumi I. Nonaka et al.   IMMUNOGENETICS

A molecule in teleost fish, related with human MHC-encoded G6F, has a cytoplasmic tail with ITAM and marks the surface of thrombocytes and in some fishes also of erythrocytes

(2010) Ken Ohashi et al.   IMMUNOGENETICS

MHC evolution in three salmonid species: a comparison between class II alpha and beta genes

(2010) Daniela Gómez et al.   IMMUNOGENETICS

MHC Class I Presentation and Regulation by IFN in Bony Fish Determined by Molecular Analysis of the Class I Locus in Grass Carp

(2010) W. Chen et al.   JOURNAL OF IMMUNOLOGY

Evolutionarily Conserved TCR Binding Sites, Identification of T Cells in Primary Lymphoid Tissues, and Surprising Trans-Rearrangements in Nurse Shark

(2010) M. F. Criscitiello et al.   JOURNAL OF IMMUNOLOGY

Confirmation and fine-mapping of a major QTL for resistance to infectious pancreatic necrosis in Atlantic salmon (Salmo salar): population-level associations between markers and trait

(2009) Thomas Moen et al.   BMC GENOMICS

Zinc-dependent binding between peptides derived from rainbow trout CD8α and LCK

(2009) Nobuhiro Hayashi et al.   FISH & SHELLFISH IMMUNOLOGY

The susceptibility of Atlantic salmon fry to freshwater infectious pancreatic necrosis is largely explained by a major QTL

(2009) R D Houston et al.   HEREDITY

Origin and evolution of the adaptive immune system: genetic events and selective pressures

(2009) Martin F. Flajnik et al.   NATURE REVIEWS GENETICS

MHC Class I: An Unexpected Role in Neuronal Plasticity

(2009) Carla J. Shatz   NEURON

Multiple expressed MHC class II loci in salmonids; details of one non-classical region in Atlantic salmon (Salmo salar)

(2008) Håvard Harstad et al.   BMC GENOMICS

Divergent patterns of selection on the DAB and DXB MHC class II loci in Xiphophorus fishes

(2008) Kyle Summers et al.   GENETICA

Major Quantitative Trait Loci Affect Resistance to Infectious Pancreatic Necrosis in Atlantic Salmon (Salmo salar)

(2008) R. D. Houston et al.   GENETICS

Suggestive Association of Major Histocompatibility IB Genetic Markers with Resistance to Bacterial Cold Water Disease in Rainbow Trout (Oncorhynchus mykiss)

(2008) Nathan A. Johnson et al.   MARINE BIOTECHNOLOGY

Transcriptional profiling of MHC class I genes in rainbow trout infected with infectious hematopoietic necrosis virus

(2008) Eric D. Landis et al.   MOLECULAR IMMUNOLOGY

Cell-mediated immune responses in rainbow trout after DNA immunization against the viral hemorrhagic septicemia virus

(2007) Katrin Utke et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY