Genomic signatures of extensive inbreeding in Isle Royale wolves, a population on the threshold of extinction

Genetics and extinction and the example of Isle Royale wolves

(2019) P. W. Hedrick et al.   ANIMAL CONSERVATION

On the path to extinction: Inbreeding and admixture in a declining grey wolf population

(2018) Daniel Gómez-Sánchez et al.   MOLECULAR ECOLOGY

Purging of Strongly Deleterious Mutations Explains Long-Term Persistence and Absence of Inbreeding Depression in Island Foxes

(2018) Jacqueline A. Robinson et al.   CURRENT BIOLOGY

Inference of the Distribution of Selection Coefficients for New Nonsynonymous Mutations Using Large Samples

(2017) Bernard Y. Kim et al.   GENETICS

Survival and divergence in a small group: The extraordinary genomic history of the endangered Apennine brown bear stragglers

(2017) Andrea Benazzo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inference of the Distribution of Selection Coefficients for New Nonsynonymous Mutations Using Large Samples

(2017) Bernard Y. Kim et al.   GENETICS

Genomic consequences of intensive inbreeding in an isolated wolf population

(2017) Marty Kardos et al.   Nature Ecology & Evolution

Genomic Flatlining in the Endangered Island Fox

(2016) Jacqueline A. Robinson et al.   CURRENT BIOLOGY

The impact of recent population history on the deleterious mutation load in humans and close evolutionary relatives

(2016) Yuval B Simons et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

SLiM 2: Flexible, Interactive Forward Genetic Simulations

(2016) Benjamin C. Haller et al.   MOLECULAR BIOLOGY AND EVOLUTION

Genetic rescue in a severely inbred wolf population

(2016) Mikael Åkesson et al.   MOLECULAR ECOLOGY

Understanding Inbreeding Depression, Purging, and Genetic Rescue

(2016) Philip W. Hedrick et al.   TRENDS IN ECOLOGY & EVOLUTION

Whole-genome sequence analysis shows that two endemic species of North American wolf are admixtures of the coyote and gray wolf

(2016) B. M. vonHoldt et al.   Science Advances

Genome-wide Evidence Reveals that African and Eurasian Golden Jackals Are Distinct Species

(2015) Klaus-Peter Koepfli et al.   CURRENT BIOLOGY

Worldwide patterns of genomic variation and admixture in gray wolves

(2015) Zhenxin Fan et al.   GENOME RESEARCH

Genetic subdivision and candidate genes under selection in North American grey wolves

(2015) Rena M. Schweizer et al.   MOLECULAR ECOLOGY

Expansion load: recessive mutations and the role of standing genetic variation

(2015) Stephan Peischl et al.   MOLECULAR ECOLOGY

Bottlenecks and selective sweeps during domestication have increased deleterious genetic variation in dogs

(2015) Clare D. Marsden et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mountain gorilla genomes reveal the impact of long-term population decline and inbreeding

(2015) Y. Xue et al.   SCIENCE

Second-generation PLINK: rising to the challenge of larger and richer datasets

(2015) Christopher C Chang et al.   GigaScience

Trophic Cascades in a Multicausal World: Isle Royale and Yellowstone

(2014) Rolf O. Peterson et al.   Annual Review of Ecology Evolution and Systematics

SNPhylo: a pipeline to construct a phylogenetic tree from huge SNP data

(2014) Tae-Ho Lee et al.   BMC GENOMICS

Genetic rescue in Isle Royale wolves: genetic analysis and the collapse of the population

(2014) Philip W. Hedrick et al.   CONSERVATION GENETICS

Status and Ecological Effects of the World's Largest Carnivores

(2014) W. J. Ripple et al.   SCIENCE

Hypoxia Adaptations in the Grey Wolf (Canis lupus chanco) from Qinghai-Tibet Plateau

(2014) Wenping Zhang et al.   PLoS Genetics

Long Runs of Homozygosity Are Enriched for Deleterious Variation

(2013) Zachary A. Szpiech et al.   AMERICAN JOURNAL OF HUMAN GENETICS

What the Inbred Scandinavian Wolf Population Tells Us about the Nature of Conservation

(2013) Jannikke Räikkönen et al.   PLoS One

The variant call format and VCFtools

(2011) P. Danecek et al.   BIOINFORMATICS

A genome-wide perspective on the evolutionary history of enigmatic wolf-like canids

(2011) Bridgett M. vonHoldt et al.   GENOME RESEARCH

Kin encounter rate and inbreeding avoidance in canids

(2011) ELI GEFFEN et al.   MOLECULAR ECOLOGY

g:Profiler—a web server for functional interpretation of gene lists (2011 update)

(2011) Jüri Reimand et al.   NUCLEIC ACIDS RESEARCH

Genomic sweep and potential genetic rescue during limiting environmental conditions in an isolated wolf population

(2011) J. R. Adams et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Diffuse idiopathic skeletal hyperostosis (DISH) and spondylosis deformans in purebred dogs: A retrospective radiographic study

(2011) Hendrik-Jan C. Kranenburg et al.   VETERINARY JOURNAL

Deriving the consequences of genomic variants with the Ensembl API and SNP Effect Predictor

(2010) William McLaren et al.   BIOINFORMATICS

Signatures of demographic bottlenecks in European wolf populations

(2010) Natalia Sastre et al.   CONSERVATION GENETICS

The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data

(2010) A. McKenna et al.   GENOME RESEARCH

Congenital bone deformities and the inbred wolves (Canis lupus) of Isle Royale

(2009) Jannikke Räikkönen et al.   BIOLOGICAL CONSERVATION

Isle Royale study affirms ability of wolves to persist

(2009) Dave Mech et al.   BIOLOGICAL CONSERVATION

Linkage Disequilibrium and Demographic History of Wild and Domestic Canids

(2009) M. M. Gray et al.   GENETICS

Predicting the effects of coding non-synonymous variants on protein function using the SIFT algorithm

(2009) Prateek Kumar et al.   Nature Protocols

The genetics of inbreeding depression

(2009) Deborah Charlesworth et al.   NATURE REVIEWS GENETICS

Proportionally more deleterious genetic variation in European than in African populations

(2008) Kirk E. Lohmueller et al.   NATURE

The genealogy and genetic viability of reintroduced Yellowstone grey wolves

(2007) BRIDGETT M. VONHOLDT et al.   MOLECULAR ECOLOGY