Oxidization of TGFβ-activated kinase by MPT53 is required for immunity to Mycobacterium tuberculosis

MicroRNA-27a controls the intracellular survival of Mycobacterium tuberculosis by regulating calcium-associated autophagy

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Mycobacterium tuberculosisLipoprotein MPT83 Induces Apoptosis of Infected Macrophages by Activating the TLR2/p38/COX-2 Signaling Pathway

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Notch4 Negatively Regulates the Inflammatory Response to Mycobacterium tuberculosis Infection by Inhibiting TAK1 Activation

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Neutrophils in tuberculosis – first line of defence or booster of disease and targets for host directed therapy?

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Isolation, semisynthesis, covalent docking and transforming growth factor beta-activated kinase 1 (TAK1)-inhibitory activities of (5Z)-7-oxozeaenol analogues

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The Cytosolic Sensor cGAS Detects Mycobacterium tuberculosis DNA to Induce Type I Interferons and Activate Autophagy

(2015) Robert O. Watson et al.   Cell Host & Microbe

The onset of adaptive immunity in the mouse model of tuberculosis and the factors that compromise its expression

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Sensing ofMycobacterium tuberculosisand consequences to both host and bacillus

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Cytokine and lipid mediator networks in tuberculosis

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Immunoevasion and immunosuppression of the macrophage byMycobacterium tuberculosis

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The balance between protective and pathogenic immune responses in the TB-infected lung

(2015) Ian M Orme et al.   NATURE IMMUNOLOGY

Mycobacterium tuberculosis suppresses innate immunity by coopting the host ubiquitin system

(2015) Jing Wang et al.   NATURE IMMUNOLOGY

Pathology and immune reactivity: understanding multidimensionality in pulmonary tuberculosis

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Interaction of Pattern Recognition Receptors with Mycobacterium Tuberculosis

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NOD2-Deficient Mice Have Impaired Resistance to Mycobacterium tuberculosis Infection through Defective Innate and Adaptive Immunity

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Progress in tuberculosis vaccine development and host-directed therapies—a state of the art review

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The Immune Response in Tuberculosis

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MicroRNA-223 controls susceptibility to tuberculosis by regulating lung neutrophil recruitment

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Cell type-specific function of TAK1 in innate immune signaling

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Mycobacterium Tuberculosis Activates the DNA-Dependent Cytosolic Surveillance Pathway within Macrophages

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Ubiquitination in signaling to and activation of IKK

(2012) Zhijian J. Chen   IMMUNOLOGICAL REVIEWS

Inhibition of TLR signaling by a bacterial protein containing immunoreceptor tyrosine-based inhibitory motifs

(2012) Dapeng Yan et al.   NATURE IMMUNOLOGY

Serine/threonine acetylation of TGF -activated kinase (TAK1) by Yersinia pestis YopJ inhibits innate immune signaling

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Targeting of TAK1 in inflammatory disorders and cancer

(2012) Hiroaki Sakurai   TRENDS IN PHARMACOLOGICAL SCIENCES

Vaccines against Tuberculosis: Where Are We and Where Do We Need to Go?

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A delicate dance: host response to mycobacteria

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Regulation of neutrophils by interferon-γ limits lung inflammation during tuberculosis infection

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A recombinant Mycobacterium smegmatis induces potent bactericidal immunity against Mycobacterium tuberculosis

(2011) Kari A Sweeney et al.   NATURE MEDICINE

NOD2 controls the nature of the inflammatory response and subsequent fate of Mycobacterium tuberculosis and M. bovis BCG in human macrophages

(2010) Michelle N. Brooks et al.   CELLULAR MICROBIOLOGY

Mycobacterium tuberculosis protein ESAT-6 is a potent activator of the NLRP3/ASC inflammasome

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Autoactivation of Transforming Growth Factor β-activated Kinase 1 Is a Sequential Bimolecular Process

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An Extracellular Disulfide Bond Forming Protein (DsbF) from Mycobacterium tuberculosis: Structural, Biochemical, and Gene Expression Analysis

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Increased NOD2-mediated recognition ofN-glycolyl muramyl dipeptide

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Direct activation of protein kinases by unanchored polyubiquitin chains

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The type I TGF-β receptor engages TRAF6 to activate TAK1 in a receptor kinase-independent manner

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