OMIC Technologies and Vaccine Development: From the Identification of Vulnerable Individuals to the Formulation of Invulnerable Vaccines

Dynamic molecular changes during the first week of human life follow a robust developmental trajectory

(2019) Amy H. Lee et al.   Nature Communications

Single-Cell Genomics: A Stepping Stone for Future Immunology Discoveries

(2018) Amir Giladi et al.   CELL

A Cost-Effective High-Throughput Plasma and Serum Proteomics Workflow Enables Mapping of the Molecular Impact of Total Pancreatectomy with Islet Autotransplantation

(2018) Tue Bjerg Bennike et al.   JOURNAL OF PROTEOME RESEARCH

Factors Associated With Persistence of Plasma HIV-1 RNA During Long-term Continuously Suppressive Firstline Antiretroviral Therapy

(2018) Alessandra Ruggiero et al.   Open Forum Infectious Diseases

First International Precision Vaccines Conference: Multidisciplinary Approaches to Next-Generation Vaccines

(2018) Francesco Borriello et al.   mSphere

Systems vaccinology and big data in the vaccine development chain

(2018) René H. M. Raeven et al.   IMMUNOLOGY

Toll-like receptor 8 agonist nanoparticles mimic immunomodulating effects of the live BCG vaccine and enhance neonatal innate and adaptive immune responses

(2017) David J. Dowling et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Induction ofIL21in Peripheral T Follicular Helper Cells Is an Indicator of Influenza Vaccine Response in a Previously Vaccinated HIV-Infected Pediatric Cohort

(2017) Lesley R. de Armas et al.   JOURNAL OF IMMUNOLOGY

Single-minded CRISPR screening

(2017) Bryan R Lanning et al.   NATURE BIOTECHNOLOGY

Simultaneous epitope and transcriptome measurement in single cells

(2017) Marlon Stoeckius et al.   NATURE METHODS

Effectiveness of Vaccination During Pregnancy to Prevent Infant Pertussis

(2017) Roger Baxter et al.   PEDIATRICS

Mapping the human DC lineage through the integration of high-dimensional techniques

(2017) Peter See et al.   SCIENCE

Personalized vaccinology: A review

(2017) G.A. Poland et al.   VACCINE

Metabolites as biomarkers of adverse reactions following vaccination: A pilot study using nuclear magnetic resonance metabolomics

(2017) Bruce M. McClenathan et al.   VACCINE

Massively parallel digital transcriptional profiling of single cells

(2017) Grace X. Y. Zheng et al.   Nature Communications

Systems Vaccinology Identifies an Early Innate Immune Signature as a Correlate of Antibody Responses to the Ebola Vaccine rVSV-ZEBOV

(2017) Anne Rechtien et al.   Cell Reports

Perturbation of B Cell Gene Expression Persists in HIV-Infected Children Despite Effective Antiretroviral Therapy and Predicts H1N1 Response

(2017) Nicola Cotugno et al.   Frontiers in Immunology

Anti-mycobacterial activity correlates with altered DNA methylation pattern in immune cells from BCG-vaccinated subjects

(2017) Deepti Verma et al.   Scientific Reports

Perturb-Seq: Dissecting Molecular Circuits with Scalable Single-Cell RNA Profiling of Pooled Genetic Screens

(2016) Atray Dixit et al.   CELL

Vaccinations for rheumatoid arthritis

(2016) Marcia A. Friedman et al.   CURRENT OPINION IN RHEUMATOLOGY

Mass spectrometric epitope mapping

(2016) Kwabena F.M. Opuni et al.   MASS SPECTROMETRY REVIEWS

Waning of vaccine-induced immunity to measles in kidney transplanted children

(2016) Salvatore Rocca et al.   MEDICINE

Efficacy of the Herpes Zoster Subunit Vaccine in Adults 70 Years of Age or Older

(2016) Anthony L. Cunningham et al.   NEW ENGLAND JOURNAL OF MEDICINE

The therapeutic potential of epigenetic manipulation during infectious diseases

(2016) Joby Cole et al.   PHARMACOLOGY & THERAPEUTICS

System-Wide Associations between DNA-Methylation, Gene Expression, and Humoral Immune Response to Influenza Vaccination

(2016) Michael T. Zimmermann et al.   PLoS One

Specification of tissue-resident macrophages during organogenesis

(2016) E. Mass et al.   SCIENCE

Vaccination of special populations: Protecting the vulnerable

(2016) Mark Doherty et al.   VACCINE

Correction: Integrative genomic analysis of the human immune response to influenza vaccination

(2016) Luis M Franco et al.   eLife

A review of guidance on immunization in persons with defective or deficient splenic function

(2015) Ernest Kuchar et al.   BRITISH JOURNAL OF HAEMATOLOGY

The influence of paediatric HIV infection on circulating B cell subsets and CXCR5+T helper cells

(2015) A. Bamford et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Infant peripheral blood repetitive element hypomethylation associated with antiretroviral therapyin utero

(2015) Carmen J Marsit et al.   Epigenetics

The role of structural proteomics in vaccine development: recent advances and future prospects

(2015) Danilo Donnarumma et al.   Expert Review of Proteomics

Defective B-cell proliferation and maintenance of long-term memory in patients with chronic granulomatous disease

(2015) Nicola Cotugno et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

SNP rs7770370 inHLA-DPB1loci as a major genetic determinant of response to booster hepatitis B vaccination: Results of a genome-wide association study

(2015) Tzu-Wei Wu et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Vaccinology in the era of high-throughput biology

(2015) H. I. Nakaya et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Masking of antigenic epitopes by antibodies shapes the humoral immune response to influenza

(2015) Veronika I. Zarnitsyna et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Proteomic contributions to our understanding of vaccine and immune responses

(2015) Allison C. Galassie et al.   Proteomics Clinical Applications

New approaches to understanding the immune response to vaccination and infection

(2015) David Furman et al.   VACCINE

Diagnosing the determinants of vaccine hesitancy in specific subgroups: The Guide to Tailoring Immunization Programmes (TIP)

(2015) Robb Butler et al.   VACCINE

Updates in vaccination: Recommendations for adult inflammatory bowel disease patients

(2015) Khadija Chaudrey et al.   WORLD JOURNAL OF GASTROENTEROLOGY

During Stably Suppressive Antiretroviral Therapy Integrated HIV-1 DNA Load in Peripheral Blood is Associated with the Frequency of CD8 Cells Expressing HLA-DR/DP/DQ

(2015) Alessandra Ruggiero et al.   EBioMedicine

Global Analyses of Human Immune Variation Reveal Baseline Predictors of Postvaccination Responses

(2014) John S. Tsang et al.   CELL

High-throughput sequencing of natively paired antibody chains provides evidence for original antigenic sin shaping the antibody response to influenza vaccination

(2014) Yann-Chong Tan et al.   CLINICAL IMMUNOLOGY

Executive Summary: 2013 IDSA Clinical Practice Guideline for Vaccination of the Immunocompromised Host

(2014) Lorry G. Rubin et al.   CLINICAL INFECTIOUS DISEASES

Polymorphisms in HLA-DPB1 Are Associated With Differences in Rubella Virus-Specific Humoral Immunity After Vaccination

(2014) N. D. Lambert et al.   JOURNAL OF INFECTIOUS DISEASES

Early Highly Active Antiretroviral Therapy Enhances B-cell Longevity

(2014) Alberto Cagigi et al.   PEDIATRIC INFECTIOUS DISEASE JOURNAL

Adjuvant Effects Elicited by Novel Oligosaccharide Variants of Detoxified Meningococcal Lipopolysaccharides on Neisseria meningitidis Recombinant PorA Protein: A Comparison in Mice

(2014) Ojas H. Mehta et al.   PLoS One

B-Sides Serologic Markers of Immunogenicity in Kidney Transplanted Patients

(2014) Stefano Rinaldi et al.   TRANSPLANTATION

Changing Face of Vaccination in Immunocompromised Hosts

(2014) Daire O’Shea et al.   Current Infectious Disease Reports

Epigenetic modulation of the immune function

(2013) Beatriz Suárez-Álvarez et al.   Epigenetics

A genome-wide association study identifies polymorphisms in the HLA-DR region associated with non-response to hepatitis B vaccination in Chinese Han populations

(2013) Liping Pan et al.   HUMAN MOLECULAR GENETICS

Systems Scale Interactive Exploration Reveals Quantitative and Qualitative Differences in Response to Influenza and Pneumococcal Vaccines

(2013) Gerlinde Obermoser et al.   IMMUNITY

Interleukin-21 and T follicular helper cells in HIV infection: research focus and future perspectives

(2013) Suresh Pallikkuth et al.   IMMUNOLOGIC RESEARCH

Premature immune senescence during HIV-1 vertical infection relates with response to influenza vaccination

(2013) Alberto Cagigi et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Apoptosis and other immune biomarkers predict influenza vaccine responsiveness

(2013) D. Furman et al.   Molecular Systems Biology

High-throughput sequencing of the paired human immunoglobulin heavy and light chain repertoire

(2013) Brandon J DeKosky et al.   NATURE BIOTECHNOLOGY

Molecular signatures of antibody responses derived from a systems biology study of five human vaccines

(2013) Shuzhao Li et al.   NATURE IMMUNOLOGY

Are cases of mumps in vaccinated patients attributable to mismatches in both vaccine T-cell and B-cell epitopes?

(2013) E Jane Homan et al.   Human Vaccines & Immunotherapeutics

Effects of influenza on pregnant women and infants

(2012) Sonja A. Rasmussen et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Suboptimal Immune Reconstitution in Vertically HIV Infected Children: A View on How HIV Replication and Timing of HAART Initiation Can Impact on T and B-cell Compartment

(2012) Nicola Cotugno et al.   Clinical & Developmental Immunology

Genome-wide genetic associations with IFNγ response to smallpox vaccine

(2012) Richard B. Kennedy et al.   HUMAN GENETICS

DNA methylation: a promising landscape for immune system-related diseases

(2012) Beatriz Suarez-Alvarez et al.   TRENDS IN GENETICS

Microbial translocation, immune activation, and HIV disease

(2012) Nichole R. Klatt et al.   TRENDS IN MICROBIOLOGY

Genome-wide association study of antibody response to smallpox vaccine

(2012) Inna G. Ovsyannikova et al.   VACCINE

Immune reconstitution and vaccination outcome in HIV-1 infected children

(2012) Alberto Cagigi et al.   Human Vaccines & Immunotherapeutics

The role of polymorphisms in Toll-like receptors and their associated intracellular signaling genes in measles vaccine immunity

(2011) Inna G. Ovsyannikova et al.   HUMAN GENETICS

Systems biology of vaccination for seasonal influenza in humans

(2011) Helder I Nakaya et al.   NATURE IMMUNOLOGY

Systems vaccinology: learning to compute the behavior of vaccine induced immunity

(2011) Helder I. Nakaya et al.   Wiley Interdisciplinary Reviews-Systems Biology and Medicine

Next-generation sequencing: a transformative tool for vaccinology

(2009) Neelam Dhiman et al.   Expert Review of Vaccines

Rubella vaccine-induced cellular immunity: evidence of associations with polymorphisms in the Toll-like, vitamin A and D receptors, and innate immune response genes

(2009) Inna G. Ovsyannikova et al.   HUMAN GENETICS

Timing of HAART defines the integrity of memory B cells and the longevity of humoral responses in HIV-1 vertically-infected children

(2009) S. Pensieroso et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Understanding biological functions through molecular networks

(2008) Jing-Dong Jackie Han   CELL RESEARCH

Immune Responses to Mumps Vaccine in Adults Who Were Vaccinated in Childhood

(2008) Rima Hanna‐Wakim et al.   JOURNAL OF INFECTIOUS DISEASES

Genetic Basis for Adverse Events after Smallpox Vaccination

(2008) David M. Reif et al.   JOURNAL OF INFECTIOUS DISEASES

Systems biology approach predicts immunogenicity of the yellow fever vaccine in humans

(2008) Troy D Querec et al.   NATURE IMMUNOLOGY

Vaccine immunogenetics: Bedside to bench to population

(2008) Gregory A. Poland et al.   VACCINE