Vaccinology in the era of high-throughput biology

CRISPR-Cas9 Knockin Mice for Genome Editing and Cancer Modeling

(2014) Randall J. Platt et al.   CELL

Global Analyses of Human Immune Variation Reveal Baseline Predictors of Postvaccination Responses

(2014) John S. Tsang et al.   CELL

An Outpatient, Ambulant-Design, Controlled Human Infection Model Using Escalating Doses of Salmonella Typhi Challenge Delivered in Sodium Bicarbonate Solution

(2014) Claire S. Waddington et al.   CLINICAL INFECTIOUS DISEASES

TLR5-Mediated Sensing of Gut Microbiota Is Necessary for Antibody Responses to Seasonal Influenza Vaccination

(2014) Jason Z. Oh et al.   IMMUNITY

ImmPort: disseminating data to the public for the future of immunology

(2014) Sanchita Bhattacharya et al.   IMMUNOLOGIC RESEARCH

Serological Responses to an Avian Influenza A/H7N9 Vaccine Mixed at the Point-of-Use With MF59 Adjuvant

(2014) Mark J. Mulligan et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Differences in Antibody Responses Between Trivalent Inactivated Influenza Vaccine and Live Attenuated Influenza Vaccine Correlate With the Kinetics and Magnitude of Interferon Signaling in Children

(2014) Raquel G. Cao et al.   JOURNAL OF INFECTIOUS DISEASES

A draft map of the human proteome

(2014) Min-Sik Kim et al.   NATURE

Unifying immunology with informatics and multiscale biology

(2014) Brian A Kidd et al.   NATURE IMMUNOLOGY

Highly multiplexed imaging of tumor tissues with subcellular resolution by mass cytometry

(2014) Charlotte Giesen et al.   NATURE METHODS

Systems vaccinology: Probing humanity's diverse immune systems with vaccines

(2014) B. Pulendran   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human metabolomics: strategies to understand biology

(2013) Rawi Ramautar et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Computational deconvolution: extracting cell type-specific information from heterogeneous samples

(2013) Shai S Shen-Orr et al.   CURRENT OPINION IN IMMUNOLOGY

Gene signatures related to B-cell proliferation predict influenza vaccine-induced antibody response

(2013) Yan Tan et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Systems Scale Interactive Exploration Reveals Quantitative and Qualitative Differences in Response to Influenza and Pneumococcal Vaccines

(2013) Gerlinde Obermoser et al.   IMMUNITY

Safety and immunogenicity of an oral, replicating adenovirus serotype 4 vector vaccine for H5N1 influenza: a randomised, double-blind, placebo-controlled, phase 1 study

(2013) Marc Gurwith et al.   LANCET INFECTIOUS DISEASES

Systematic identification of trans eQTLs as putative drivers of known disease associations

(2013) Harm-Jan Westra et al.   NATURE GENETICS

Vaccine Activation of the Nutrient Sensor GCN2 in Dendritic Cells Enhances Antigen Presentation

(2013) R. Ravindran et al.   SCIENCE

Systems immunogenetics of vaccines

(2013) Michael Mooney et al.   SEMINARS IN IMMUNOLOGY

Systems biological approaches to measure and understand vaccine immunity in humans

(2013) Shuzhao Li et al.   SEMINARS IN IMMUNOLOGY

Integrative genomic analysis of the human immune response to influenza vaccination

(2013) Luis M Franco et al.   eLife

Plasticity and Virus Specificity of the Airway Epithelial Cell Immune Response during Respiratory Virus Infection

(2012) I. Ioannidis et al.   JOURNAL OF VIROLOGY

Host Immune Transcriptional Profiles Reflect the Variability in Clinical Disease Manifestations in Patients with Staphylococcus aureus Infections

(2012) Romain Banchereau et al.   PLoS One

Molecular signatures database (MSigDB) 3.0

(2011) A. Liberzon et al.   BIOINFORMATICS

Challenges and opportunities of metabolomics

(2011) Caroline H. Johnson et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Systems biology of vaccination for seasonal influenza in humans

(2011) Helder I Nakaya et al.   NATURE IMMUNOLOGY

Immunological mechanisms of vaccination

(2011) Bali Pulendran et al.   NATURE IMMUNOLOGY

Oil-in-Water Emulsion Adjuvant with Influenza Vaccine in Young Children

(2011) Timo Vesikari et al.   NEW ENGLAND JOURNAL OF MEDICINE

MF59 Adjuvant Enhances Diversity and Affinity of Antibody-Mediated Immune Response to Pandemic Influenza Vaccines

(2011) S. Khurana et al.   Science Translational Medicine

Systems vaccinology: learning to compute the behavior of vaccine induced immunity

(2011) Helder I. Nakaya et al.   Wiley Interdisciplinary Reviews-Systems Biology and Medicine

Systems vaccinology

(2011) Helder I. Nakaya et al.   Current Opinion in HIV and AIDS

Systems Vaccinology

(2010) Bali Pulendran et al.   IMMUNITY

Expression of Genes Associated with Immunoproteasome Processing of Major Histocompatibility Complex Peptides Is Indicative of Protection with Adjuvanted RTS,S Malaria Vaccine

(2010) Maryanne T. Vahey et al.   JOURNAL OF INFECTIOUS DISEASES

Identifying HIV-1 host cell factors by genome-scale RNAi screening

(2010) Lars Pache et al.   METHODS

An interferon-inducible neutrophil-driven blood transcriptional signature in human tuberculosis

(2010) Matthew P. R. Berry et al.   NATURE

Yellow fever vaccine—how does it work and why do rare cases of serious adverse events take place?

(2009) Alan DT Barrett et al.   CURRENT OPINION IN IMMUNOLOGY

Enhancing CD8 T-cell memory by modulating fatty acid metabolism

(2009) Erika L. Pearce et al.   NATURE

Understanding biological functions through molecular networks

(2008) Jing-Dong Jackie Han   CELL RESEARCH

A Modular Analysis Framework for Blood Genomics Studies: Application to Systemic Lupus Erythematosus

(2008) Damien Chaussabel et al.   IMMUNITY

Systems biology of innate immunity

(2008) Daniel E. Zak et al.   IMMUNOLOGICAL REVIEWS

Yellow fever vaccine induces integrated multilineage and polyfunctional immune responses

(2008) Denis Gaucher et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Rapid cloning of high-affinity human monoclonal antibodies against influenza virus

(2008) Jens Wrammert et al.   NATURE

Systems biology approach predicts immunogenicity of the yellow fever vaccine in humans

(2008) Troy D Querec et al.   NATURE IMMUNOLOGY

PID: the Pathway Interaction Database

(2008) Carl F. Schaefer et al.   NUCLEIC ACIDS RESEARCH