Microvascular bioengineering: a focus on pericytes

Rapid Self-Assembly of Bioengineered Cardiovascular Bypass Grafts From Scaffold-Stabilized, Tubular Bilevel Cell Sheets

(2019) Daniel von Bornstädt et al.   CIRCULATION

3D self-organized microvascular model of the human blood-brain barrier with endothelial cells, pericytes and astrocytes

(2018) Marco Campisi et al.   BIOMATERIALS

The controversial origin of pericytes during angiogenesis – Implications for cell-based therapeutic angiogenesis and cell-based therapies

(2018) Anna Blocki et al.   CLINICAL HEMORHEOLOGY AND MICROCIRCULATION

Severity of arterial defects in the retina correlates with the burden of intracerebral haemorrhage in COL4A1-related stroke

(2018) Julien Ratelade et al.   JOURNAL OF PATHOLOGY

Establishment and characterization of an embryonic pericyte cell line

(2018) Huaning Zhao et al.   MICROCIRCULATION

Enhancing cancer immunotherapy using antiangiogenics: opportunities and challenges

(2018) Dai Fukumura et al.   Nature Reviews Clinical Oncology

Vascular Compartmentalization of Functional Hyperemia from the Synapse to the Pia

(2018) Ravi L. Rungta et al.   NEURON

Shear Conditioning of Adipose Stem Cells for Reduced Platelet Binding to Engineered Vascular Grafts

(2018) Anh La et al.   TISSUE ENGINEERING PART A

Insights into cerebral haemodynamics and oxygenation utilising in vivo mural cell imaging and mathematical modelling

(2018) Paul W. Sweeney et al.   Scientific Reports

Spatiotemporal endothelial cell – pericyte association in tumors as shown by high resolution 4D intravital imaging

(2018) Ann L. B. Seynhaeve et al.   Scientific Reports

Dynamic Remodeling of Pericytes In Vivo Maintains Capillary Coverage in the Adult Mouse Brain

(2018) Andrée-Anne Berthiaume et al.   Cell Reports

Pericyte Structural Remodeling in Cerebrovascular Health and Homeostasis

(2018) Andrée-Anne Berthiaume et al.   Frontiers in Aging Neuroscience

Capillary pericytes express α-smooth muscle actin, which requires prevention of filamentous-actin depolymerization for detection

(2018) Luis Alarcon-Martinez et al.   eLife

Excess vascular endothelial growth factor-A disrupts pericyte recruitment during blood vessel formation

(2018) Jordan Darden et al.   ANGIOGENESIS

Molecular Architecture of the Mouse Nervous System

(2018) Amit Zeisel et al.   CELL

A molecular atlas of cell types and zonation in the brain vasculature

(2018) Michael Vanlandewijck et al.   NATURE

Molecular programming of perivascular stem cell precursors

(2018) Val Yianni et al.   STEM CELLS

Single-cell RNA sequencing of mouse brain and lung vascular and vessel-associated cell types

(2018) Liqun He et al.   Scientific Data

Organizational hierarchy and structural diversity of microvascular pericytes in adult mouse cortex

(2017) Roger I Grant et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Visualization of vascular mural cells in developing brain using genetically labeled transgenic reporter mice

(2017) Bongnam Jung et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

A vascularized and perfused organ-on-a-chip platform for large-scale drug screening applications

(2017) Duc T. T. Phan et al.   LAB ON A CHIP

Microfluidics Technologies and Approaches for Studying the Microcirculation

(2017) Walter L. Murfee et al.   MICROCIRCULATION

Microfluidic approaches to the study of angiogenesis and the microcirculation

(2017) Ehsan Akbari et al.   MICROCIRCULATION

Agent-based computational model of retinal angiogenesis simulates microvascular network morphology as a function of pericyte coverage

(2017) Joseph Walpole et al.   MICROCIRCULATION

Pericytes impair capillary blood flow and motor function after chronic spinal cord injury

(2017) Yaqing Li et al.   NATURE MEDICINE

Pericyte degeneration leads to neurovascular uncoupling and limits oxygen supply to brain

(2017) Kassandra Kisler et al.   NATURE NEUROSCIENCE

Single-cell analysis of experience-dependent transcriptomic states in the mouse visual cortex

(2017) Sinisa Hrvatin et al.   NATURE NEUROSCIENCE

Pericytes regulate VEGF-induced endothelial sprouting through VEGFR1

(2017) Hanna M. Eilken et al.   Nature Communications

Capillary pericytes mediate coronary no-reflow after myocardial ischaemia

(2017) Fergus M O'Farrell et al.   eLife

Engineering the human blood-brain barrier in vitro

(2017) John J. Jamieson et al.   Journal of Biological Engineering

A Low Permeability Microfluidic Blood-Brain Barrier Platform with Direct Contact between Perfusable Vascular Network and Astrocytes

(2017) Seokyoung Bang et al.   Scientific Reports

Flt-1 (VEGFR-1) coordinates discrete stages of blood vessel formation

(2016) John C. Chappell et al.   CARDIOVASCULAR RESEARCH

Platelet-derived Growth Factor Receptor-beta is Differentially Regulated in Primary Mouse Pericytes and Brain Slices

(2016) Bianca Hutter-Schmid et al.   CURRENT NEUROVASCULAR RESEARCH

Estimating oxygen distribution from vasculature in three-dimensional tumour tissue

(2016) David Robert Grimes et al.   Journal of the Royal Society Interface

Brain and Retinal Pericytes: Origin, Function and Role

(2016) Andrea Trost et al.   Frontiers in Cellular Neuroscience

Pericyte Seeded Dual Peptide Scaffold with Improved Endothelialization for Vascular Graft Tissue Engineering

(2016) Paola Campagnolo et al.   Advanced Healthcare Materials

Synchronization of endothelial Dll4-Notch dynamics switch blood vessels from branching to expansion

(2016) Benedetta Ubezio et al.   eLife

3D microtumors in vitro supported by perfused vascular networks

(2016) Agua Sobrino et al.   Scientific Reports

Analysis of the brain mural cell transcriptome

(2016) Liqun He et al.   Scientific Reports

Interstitial pericytes decrease in aged mouse kidneys

(2015) Ania Stefanska et al.   Aging-US

Establishment and Dysfunction of the Blood-Brain Barrier

(2015) Zhen Zhao et al.   CELL

Pericytes at the intersection between tissue regeneration and pathology: Figure 1

(2015) Alexander Birbrair et al.   CLINICAL SCIENCE

Cdc42 is required for cytoskeletal support of endothelial cell adhesion during blood vessel formation in mice

(2015) D. M. Barry et al.   DEVELOPMENT

Agent-based model of angiogenesis simulates capillary sprout initiation in multicellular networks

(2015) J. Walpole et al.   Integrative Biology

Krogh-Cylinder and Infinite-Domain Models for Washout of an Inert Diffusible Solute from Tissue

(2015) Timothy W. Secomb   MICROCIRCULATION

Human Microvascular Pericyte Basement Membrane Remodeling Regulates Neutrophil Recruitment

(2015) Parid Sava et al.   MICROCIRCULATION

Numerical modeling of drug delivery in a dynamic solid tumor microvasculature

(2015) M. Sefidgar et al.   MICROVASCULAR RESEARCH

Regional Blood Flow in the Normal and Ischemic Brain Is Controlled by Arteriolar Smooth Muscle Cell Contractility and Not by Capillary Pericytes

(2015) Robert A. Hill et al.   NEURON

Shedding of soluble platelet-derived growth factor receptor-β from human brain pericytes

(2015) Abhay P. Sagare et al.   NEUROSCIENCE LETTERS

Cell types in the mouse cortex and hippocampus revealed by single-cell RNA-seq

(2015) A. Zeisel et al.   SCIENCE

Applications of computational models to better understand microvascular remodelling: a focus on biomechanical integration across scales

(2015) Walter L. Murfee et al.   Interface Focus

Combined deficiency of Notch1 and Notch3 causes pericyte dysfunction, models CADASIL and results in arteriovenous malformations

(2015) Natalie M. Kofler et al.   Scientific Reports

Multiple Retinal Axons Converge onto Relay Cells in the Adult Mouse Thalamus

(2015) Sarah Hammer et al.   Cell Reports

Pericytes are progenitors for coronary artery smooth muscle

(2015) Katharina S Volz et al.   eLife

Retinal Microangiopathy in a Mouse Model of Inducible Mural Cell Loss

(2014) Cammi N. Valdez et al.   AMERICAN JOURNAL OF PATHOLOGY

Type-2 pericytes participate in normal and tumoral angiogenesis

(2014) Alexander Birbrair et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Coupling Mechanism and Significance of the BOLD Signal: A Status Report

(2014) Elizabeth M.C. Hillman   Annual Review of Neuroscience

Tissue-engineered microenvironment systems for modeling human vasculature

(2014) Anna Tourovskaia et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex

(2014) Y. Zhang et al.   JOURNAL OF NEUROSCIENCE

Modelling capillary oxygen supply capacity in mixed muscles: Capillary domains revisited

(2014) Abdullah A. Al-Shammari et al.   JOURNAL OF THEORETICAL BIOLOGY

Capillary pericytes regulate cerebral blood flow in health and disease

(2014) Catherine N. Hall et al.   NATURE

The role of differential VE-cadherin dynamics in cell rearrangement during angiogenesis

(2014) Katie Bentley et al.   NATURE CELL BIOLOGY

Leukocyte extravasation and vascular permeability are each controlled in vivo by different tyrosine residues of VE-cadherin

(2014) Florian Wessel et al.   NATURE IMMUNOLOGY

Imaging pericytes and capillary diameter in brain slices and isolated retinae

(2014) Anusha Mishra et al.   Nature Protocols

A role for pericytes in coronary no-reflow

(2014) Fergus M. O'Farrell et al.   Nature Reviews Cardiology

Cerebral Small Vessel Disease

(2014) Anne Joutel et al.   STROKE

Type-1 pericytes accumulate after tissue injury and produce collagen in an organ-dependent manner

(2014) Alexander Birbrair et al.   Stem Cell Research & Therapy

Multiscale Computational Models of Complex Biological Systems

(2013) Joseph Walpole et al.   Annual Review of Biomedical Engineering

Pericytes modulate endothelial sprouting

(2013) William G. Chang et al.   CARDIOVASCULAR RESEARCH

A systems biology view of blood vessel growth and remodelling

(2013) Elizabeth A. Logsdon et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Targeting Pericytes for Angiogenic Therapies

(2013) Molly R. Kelly-Goss et al.   MICROCIRCULATION

Pericytes Derived from Adipose-Derived Stem Cells Protect against Retinal Vasculopathy

(2013) Thomas A. Mendel et al.   PLoS One

Interstitial Fluid Flow and Drug Delivery in Vascularized Tumors: A Computational Model

(2013) Michael Welter et al.   PLoS One

Self-organized vascular networks from human pluripotent stem cells in a synthetic matrix

(2013) S. Kusuma et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role of Pericytes in Skeletal Muscle Regeneration and Fat Accumulation

(2013) Alexander Birbrair et al.   STEM CELLS AND DEVELOPMENT

In Vitro Perfused Human Capillary Networks

(2013) Monica L. Moya et al.   TISSUE ENGINEERING PART C-METHODS

Angiogenesis: An Adaptive Dynamic Biological Patterning Problem

(2013) Timothy W. Secomb et al.   PLoS Computational Biology

Photoreceptor avascular privilege is shielded by soluble VEGF receptor-1

(2013) Ling Luo et al.   eLife

Pericytes promote selective vessel regression to regulate vascular patterning

(2012) N. Simonavicius et al.   BLOOD

Study of normal and pathological blood vessel morphogenesis in Flt1-tdsRed BAC Tg mice

(2012) Ken Matsumoto et al.   GENESIS

Diabetic Retinopathy

(2012) David A. Antonetti et al.   NEW ENGLAND JOURNAL OF MEDICINE

Three-dimensional microfluidic model for tumor cell intravasation and endothelial barrier function

(2012) I. K. Zervantonakis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The promotion of microvasculature formation in poly(ethylene glycol) diacrylate hydrogels by an immobilized VEGF-mimetic peptide

(2011) Julia E. Leslie-Barbick et al.   BIOMATERIALS

Basic and Therapeutic Aspects of Angiogenesis

(2011) Michael Potente et al.   CELL

Vascular Smooth Muscle Progenitor Cells

(2011) Mark W. Majesky et al.   CIRCULATION RESEARCH

PDGFRβ Signaling Regulates Mural Cell Plasticity and Inhibits Fat Development

(2011) Lorin E. Olson et al.   DEVELOPMENTAL CELL

Pericytes: Developmental, Physiological, and Pathological Perspectives, Problems, and Promises

(2011) Annika Armulik et al.   DEVELOPMENTAL CELL

In vitro modeling of the microvascular occlusion and thrombosis that occur in hematologic diseases using microfluidic technology

(2011) Michelle Tsai et al.   JOURNAL OF CLINICAL INVESTIGATION

Central nervous system pericytes in health and disease

(2011) Ethan A Winkler et al.   NATURE NEUROSCIENCE

Dual origin of mesenchymal stem cells contributing to organ growth and repair

(2011) J. Feng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multiple stromal populations contribute to pulmonary fibrosis without evidence for epithelial to mesenchymal transition

(2011) J. R. Rock et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

NG2 cells: Properties, progeny and origin

(2010) Jacqueline Trotter et al.   BRAIN RESEARCH REVIEWS

Anchorage of VEGF to the extracellular matrix conveys differential signaling responses to endothelial cells

(2010) Tom T. Chen et al.   JOURNAL OF CELL BIOLOGY

Pericytes regulate the blood–brain barrier

(2010) Annika Armulik et al.   NATURE

Pericytes are required for blood–brain barrier integrity during embryogenesis

(2010) Richard Daneman et al.   NATURE

Endothelial cells dynamically compete for the tip cell position during angiogenic sprouting

(2010) Lars Jakobsson et al.   NATURE CELL BIOLOGY

Pericytes Control Key Neurovascular Functions and Neuronal Phenotype in the Adult Brain and during Brain Aging

(2010) Robert D. Bell et al.   NEURON

The Mouse Blood-Brain Barrier Transcriptome: A New Resource for Understanding the Development and Function of Brain Endothelial Cells

(2010) Richard Daneman et al.   PLoS One

Pericytes in capillaries are contractile in vivo, but arterioles mediate functional hyperemia in the mouse brain

(2010) F. Fernandez-Klett et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Contrasting Actions of Selective Inhibitors of Angiopoietin-1 and Angiopoietin-2 on the Normalization of Tumor Blood Vessels

(2009) Beverly L. Falcón et al.   AMERICAN JOURNAL OF PATHOLOGY

Shear Stress Increases Expression of the Arterial Endothelial Marker EphrinB2 in Murine ES Cells via the VEGF-Notch Signaling Pathways

(2009) Tomomi Masumura et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Pericyte recruitment during vasculogenic tube assembly stimulates endothelial basement membrane matrix formation

(2009) A. N. Stratman et al.   BLOOD

Guidance of Vascular Development

(2009) Bruno Larrivée et al.   CIRCULATION RESEARCH

NOTCH3 Expression Is Induced in Mural Cells Through an Autoregulatory Loop That Requires Endothelial-Expressed JAGGED1

(2009) Hua Liu et al.   CIRCULATION RESEARCH

Local Guidance of Emerging Vessel Sprouts Requires Soluble Flt-1

(2009) John C. Chappell et al.   DEVELOPMENTAL CELL

VE-PTP controls blood vessel development by balancing Tie-2 activity

(2009) Mark Winderlich et al.   JOURNAL OF CELL BIOLOGY

Activation of PKC-δ and SHP-1 by hyperglycemia causes vascular cell apoptosis and diabetic retinopathy

(2009) Pedro Geraldes et al.   NATURE MEDICINE

Mural Cell Associated VEGF Is Required for Organotypic Vessel Formation

(2009) Lasse Evensen et al.   PLoS One

VEGFR1-mediated pericyte ablation links VEGF and PlGF to cancer-associated retinopathy

(2009) R. Cao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Presence of VEGF Receptors on the Luminal Surface of Endothelial Cells Affects VEGF Distribution and VEGF Signaling

(2009) Marianne O. Stefanini et al.   PLoS Computational Biology

Tipping the Balance: Robustness of Tip Cell Selection, Migration and Fusion in Angiogenesis

(2009) Katie Bentley et al.   PLoS Computational Biology

Pericytes and Perivascular Fibroblasts Are the Primary Source of Collagen-Producing Cells in Obstructive Fibrosis of the Kidney

(2008) Shuei-Liong Lin et al.   AMERICAN JOURNAL OF PATHOLOGY

Fluid shear stress modulates endothelial cell invasion into three-dimensional collagen matrices

(2008) Hojin Kang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

All MSCs Are Pericytes?

(2008) Arnold I. Caplan   Cell Stem Cell

A Perivascular Origin for Mesenchymal Stem Cells in Multiple Human Organs

(2008) Mihaela Crisan et al.   Cell Stem Cell

Notch Signaling Regulates Platelet-Derived Growth Factor Receptor-β Expression in Vascular Smooth Muscle Cells

(2008) Shaobo Jin et al.   CIRCULATION RESEARCH

Pericyte Migration: A Novel Mechanism of Pericyte Loss in Experimental Diabetic Retinopathy

(2008) F. Pfister et al.   DIABETES

Fluid shear stress induces arterial differentiation of endothelial progenitor cells

(2008) Syotaro Obi et al.   JOURNAL OF APPLIED PHYSIOLOGY

Design, fabrication and implementation of a novel multi-parameter control microfluidic platform for three-dimensional cell culture and real-time imaging

(2008) Vernella Vickerman et al.   LAB ON A CHIP

Simulating brain tumor heterogeneity with a multiscale agent-based model: Linking molecular signatures, phenotypes and expansion rate

(2008) Le Zhang et al.   MATHEMATICAL AND COMPUTER MODELLING

Systems Biology of Vascular Endothelial Growth Factors

(2008) Feilim Mac Gabhann et al.   MICROCIRCULATION

A role for VEGF as a negative regulator of pericyte function and vessel maturation

(2008) Joshua I. Greenberg et al.   NATURE

Mechanotransduction in vascular physiology and atherogenesis

(2008) Cornelia Hahn et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Endothelial expression of the Notch ligand Jagged1 is required for vascular smooth muscle development

(2008) F. A. High et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

White Fat Progenitor Cells Reside in the Adipose Vasculature

(2008) W. Tang et al.   SCIENCE

Laminin deposition is dispensable for vasculogenesis but regulates blood vessel diameter independent of flow

(2007) Lars Jakobsson et al.   FASEB JOURNAL

Agent-based simulation of notch-mediated tip cell selection in angiogenic sprout initialisation

(2007) Katie Bentley et al.   JOURNAL OF THEORETICAL BIOLOGY