The Influence of the Gut Microbiome on Host Metabolism Through the Regulation of Gut Hormone Release

Commentary: The Potential Role of the Dipeptidyl Peptidase-4-Like Activity From the Gut Microbiota on the Host Health

(2019) Ronivaldo Rodrigues Da Silva   Frontiers in Microbiology

Evidence that TLR4 Is Not a Receptor for Saturated Fatty Acids but Mediates Lipid-Induced Inflammation by Reprogramming Macrophage Metabolism

(2018) Graeme I. Lancaster et al.   Cell Metabolism

The DPP-4 inhibitor vildagliptin impacts the gut microbiota and prevents disruption of intestinal homeostasis induced by a Western diet in mice

(2018) Marta Olivares et al.   DIABETOLOGIA

Augmented capacity for peripheral serotonin release in human obesity

(2018) Richard L. Young et al.   INTERNATIONAL JOURNAL OF OBESITY

What is the role of endogenous gut serotonin in the control of gastrointestinal motility?

(2018) Damien J. Keating et al.   PHARMACOLOGICAL RESEARCH

Antibiotic-induced microbiome depletion alters metabolic homeostasis by affecting gut signaling and colonic metabolism

(2018) Amir Zarrinpar et al.   Nature Communications

Microbiota derived short chain fatty acids promote histone crotonylation in the colon through histone deacetylases

(2018) Rachel Fellows et al.   Nature Communications

Gastrointestinal Transit Time, Glucose Homeostasis and Metabolic Health: Modulation by Dietary Fibers

(2018) et al.   Nutrients

Microbial regulation of the L cell transcriptome

(2018) Tulika Arora et al.   Scientific Reports

Enterochromaffin 5-HT cells – A major target for GLP-1 and gut microbial metabolites

(2018) Mari L. Lund et al.   Molecular Metabolism

Bile acids are important direct and indirect regulators of the secretion of appetite- and metabolism-regulating hormones from the gut and pancreas

(2018) Rune E. Kuhre et al.   Molecular Metabolism

Microbial Eukaryotes: a Missing Link in Gut Microbiome Studies

(2018) Isabelle Laforest-Lapointe et al.   mSystems

ABNORMAL ABSORPTIVE COLONIC MOTOR ACTIVITY IN GERM FREE MICE IS RECTIFIED BY BUTYRATE, AN EFFECT POSSIBLY MEDIATED BY MUCOSAL SEROTONIN

(2018) Alexander D Vincent et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Functional Gut Microbiota Remodeling Contributes to the Caloric Restriction-Induced Metabolic Improvements

(2018) Salvatore Fabbiano et al.   Cell Metabolism

Gut carbohydrate inhibits GIP secretion via a microbiota/SCFA/FFAR3 pathway

(2018) Eun Young Lee et al.   JOURNAL OF ENDOCRINOLOGY

SCFAs strongly stimulate PYY production in human enteroendocrine cells

(2018) P. Larraufie et al.   Scientific Reports

US Immigration Westernizes the Human Gut Microbiome

(2018) Pajau Vangay et al.   CELL

The Diverse Metabolic Roles of Peripheral Serotonin

(2017) Alyce M. Martin et al.   ENDOCRINOLOGY

Costorage of Enteroendocrine Hormones Evaluated at the Cell and Subcellular Levels in Male Mice

(2017) Linda J. Fothergill et al.   ENDOCRINOLOGY

Farnesoid X receptor induces Takeda G-protein receptor 5 cross-talk to regulate bile acid synthesis and hepatic metabolism

(2017) Preeti Pathak et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Metformin alters the gut microbiome of individuals with treatment-naive type 2 diabetes, contributing to the therapeutic effects of the drug

(2017) Hao Wu et al.   NATURE MEDICINE

The nutrient-sensing repertoires of mouse enterochromaffin cells differ between duodenum and colon

(2017) A. M. Martin et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Chemical transformation of xenobiotics by the human gut microbiota

(2017) Nitzan Koppel et al.   SCIENCE

First Insights into the Diverse Human Archaeome: Specific Detection of Archaea in the Gastrointestinal Tract, Lung, and Nose and on Skin

(2017) Kaisa Koskinen et al.   mBio

Enteroendocrine L Cells Sense LPS after Gut Barrier Injury to Enhance GLP-1 Secretion

(2017) Lorène J. Lebrun et al.   Cell Reports

Antibiotic-Induced Alterations in Gut Microbiota Are Associated with Changes in Glucose Metabolism in Healthy Mice

(2017) Richard R. Rodrigues et al.   Frontiers in Microbiology

Host–microbiota interaction induces bi-phasic inflammation and glucose intolerance in mice

(2017) Antonio Molinaro et al.   Molecular Metabolism

Fermentable carbohydrate stimulates FFAR2-dependent colonic PYY cell expansion to increase satiety

(2017) Lucy Brooks et al.   Molecular Metabolism

Divergent Relationships between Fecal Microbiota and Metabolome following Distinct Antibiotic-Induced Disruptions

(2017) Jocelyn M. Choo et al.   mSphere

The artificial sweetener acesulfame potassium affects the gut microbiome and body weight gain in CD-1 mice

(2017) Xiaoming Bian et al.   PLoS One

From Dietary Fiber to Host Physiology: Short-Chain Fatty Acids as Key Bacterial Metabolites

(2016) Ara Koh et al.   CELL

A Dietary Fiber-Deprived Gut Microbiota Degrades the Colonic Mucus Barrier and Enhances Pathogen Susceptibility

(2016) Mahesh S. Desai et al.   CELL

TLR ligands and butyrate increasePyyexpression through two distinct but inter-regulated pathways

(2016) Pierre Larraufie et al.   CELLULAR MICROBIOLOGY

Exocytosis in non-neuronal cells

(2016) Peter Thorn et al.   JOURNAL OF NEUROCHEMISTRY

From gut dysbiosis to altered brain function and mental illness: mechanisms and pathways

(2016) G B Rogers et al.   MOLECULAR PSYCHIATRY

Human gut microbes impact host serum metabolome and insulin sensitivity

(2016) Helle Krogh Pedersen et al.   NATURE

Diet drives quick changes in the metabolic activity and composition of human gut microbiota in a validated in vitro gut model

(2016) Marisol Aguirre et al.   RESEARCH IN MICROBIOLOGY

Microbial regulation of GLP-1 and L-cell biology

(2016) Thomas U. Greiner et al.   Molecular Metabolism

Colonic transit time is related to bacterial metabolism and mucosal turnover in the gut

(2016) Henrik M. Roager et al.   Nature Microbiology

Indigenous Bacteria from the Gut Microbiota Regulate Host Serotonin Biosynthesis

(2015) Jessica M. Yano et al.   CELL

The Role of Gut Adaptation in the Potent Effects of Multiple Bariatric Surgeries on Obesity and Diabetes

(2015) Randy J. Seeley et al.   Cell Metabolism

The human gut microbiota and virome: Potential therapeutic implications

(2015) Emidio Scarpellini et al.   DIGESTIVE AND LIVER DISEASE

The effect of past antibiotic exposure on diabetes risk

(2015) B. Boursi et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Gut microbes promote colonic serotonin production through an effect of short-chain fatty acids on enterochromaffin cells

(2015) Christopher S. Reigstad et al.   FASEB JOURNAL

Gut Serotonin Is a Regulator of Obesity and Metabolism

(2015) Richard L. Young et al.   GASTROENTEROLOGY

Akkermansia muciniphilaand improved metabolic health during a dietary intervention in obesity: relationship with gut microbiome richness and ecology

(2015) Maria Carlota Dao et al.   GUT

Stool consistency is strongly associated with gut microbiota richness and composition, enterotypes and bacterial growth rates

(2015) Doris Vandeputte et al.   GUT

Fusion Pore Size Limits 5-HT Release From Single Enterochromaffin Cell Vesicles

(2015) Ravinarayan Raghupathi et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Short-chain fatty acid sensing in rat duodenum

(2015) Yasutada Akiba et al.   JOURNAL OF PHYSIOLOGY-LONDON

CrossTalk opposing view: 5-HT is not necessary for peristalsis

(2015) Nick J. Spencer et al.   JOURNAL OF PHYSIOLOGY-LONDON

Microbiota depletion promotes browning of white adipose tissue and reduces obesity

(2015) Nicolas Suárez-Zamorano et al.   NATURE MEDICINE

Serotonin-secreting enteroendocrine cells respond via diverse mechanisms to acute and chronic changes in glucose availability

(2015) Leah Zelkas et al.   Nutrition & Metabolism

Regulation of energy homeostasis by the NPY system

(2015) Kim Loh et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Effect of Antibiotics on Gut Microbiota, Gut Hormones and Glucose Metabolism

(2015) Kristian H. Mikkelsen et al.   PLoS One

Role of the Microbiota in Immunity and Inflammation

(2014) Yasmine Belkaid et al.   CELL

GLP-1 as a Mediator in the Remission of Type 2 Diabetes After Gastric Bypass and Sleeve Gastrectomy Surgery

(2014) S. Madsbad et al.   DIABETES

Insights Into the Role of the Microbiome in Obesity and Type 2 Diabetes

(2014) Annick V. Hartstra et al.   DIABETES CARE

Role of the Microbiome in Energy Regulation and Metabolism

(2014) Max Nieuwdorp et al.   GASTROENTEROLOGY

The short chain fatty acid propionate stimulates GLP-1 and PYY secretion via free fatty acid receptor 2 in rodents

(2014) A Psichas et al.   INTERNATIONAL JOURNAL OF OBESITY

Artificial sweeteners induce glucose intolerance by altering the gut microbiota

(2014) Jotham Suez et al.   NATURE

Inhibiting peripheral serotonin synthesis reduces obesity and metabolic dysfunction by promoting brown adipose tissue thermogenesis

(2014) Justin D Crane et al.   NATURE MEDICINE

Effect of Peripheral 5-HT on Glucose and Lipid Metabolism in Wether Sheep

(2014) Hitoshi Watanabe et al.   PLoS One

Gut microbiota and energy balance: role in obesity

(2014) Michael Blaut   PROCEEDINGS OF THE NUTRITION SOCIETY

Bacterial Metabolite Indole Modulates Incretin Secretion from Intestinal Enteroendocrine L Cells

(2014) Catalin Chimerel et al.   Cell Reports

Serotonin and cholecystokinin mediate nutrient-induced segmentation in guinea pig small intestine

(2013) Melina Ellis et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Free Fatty Acid (FFA) and Hydroxy Carboxylic Acid (HCA) Receptors

(2013) Stefan Offermanns   Annual Review of Pharmacology and Toxicology

Lipopolysaccharides-Mediated Increase in Glucose-Stimulated Insulin Secretion: Involvement of the GLP-1 Pathway

(2013) A. T. Nguyen et al.   DIABETES

Impact of oral vancomycin on gut microbiota, bile acid metabolism, and insulin sensitivity

(2013) Anne Vrieze et al.   JOURNAL OF HEPATOLOGY

Identification of unique release kinetics of serotonin from guinea-pig and human enterochromaffin cells

(2013) Ravinarayan Raghupathi et al.   JOURNAL OF PHYSIOLOGY-LONDON

Richness of human gut microbiome correlates with metabolic markers

(2013) Emmanuelle Le Chatelier et al.   NATURE

Diet rapidly and reproducibly alters the human gut microbiome

(2013) Lawrence A. David et al.   NATURE

Bacterial Community Mapping of the Mouse Gastrointestinal Tract

(2013) Shenghua Gu et al.   PLoS One

Gut Microbiota from Twins Discordant for Obesity Modulate Metabolism in Mice

(2013) V. K. Ridaura et al.   SCIENCE

Cholecystokinin

(2013) Graham J. Dockray   Current Opinion in Endocrinology Diabetes and Obesity

Gut-Derived Serotonin Is a Multifunctional Determinant to Fasting Adaptation

(2012) Grzegorz Sumara et al.   Cell Metabolism

Efficacy of GLP-1 Receptor Agonists and DPP-4 Inhibitors: Meta-Analysis and Systematic Review

(2012) Vanita R. Aroda et al.   CLINICAL THERAPEUTICS

Transfer of Intestinal Microbiota From Lean Donors Increases Insulin Sensitivity in Individuals With Metabolic Syndrome

(2012) Anne Vrieze et al.   GASTROENTEROLOGY

Dietary-fat-induced taurocholic acid promotes pathobiont expansion and colitis in Il10 −/− mice

(2012) Suzanne Devkota et al.   NATURE

Functional interactions between the gut microbiota and host metabolism

(2012) Valentina Tremaroli et al.   NATURE

Antibiotics in early life alter the murine colonic microbiome and adiposity

(2012) Ilseung Cho et al.   NATURE

Increased Gut Permeability and Microbiota Change Associate with Mesenteric Fat Inflammation and Metabolic Dysfunction in Diet-Induced Obese Mice

(2012) Yan Y. Lam et al.   PLoS One

Butyrate and Propionate Protect against Diet-Induced Obesity and Regulate Gut Hormones via Free Fatty Acid Receptor 3-Independent Mechanisms

(2012) Hua V. Lin et al.   PLoS One

Increased Oral Detection, but Decreased Intestinal Signaling for Fats in Mice Lacking Gut Microbiota

(2012) Frank A. Duca et al.   PLoS One

Mechanisms underlying distension-evoked peristalsis in guinea pig distal colon: is there a role for enterochromaffin cells?

(2011) Nick J. Spencer et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Short-Chain Fatty Acids Stimulate Glucagon-Like Peptide-1 Secretion via the G-Protein-Coupled Receptor FFAR2

(2011) G. Tolhurst et al.   DIABETES

Release of 5-Hydroxytryptamine From the Mucosa Is Not Required for the Generation or Propagation of Colonic Migrating Motor Complexes

(2009) Damien J. Keating et al.   GASTROENTEROLOGY

Suppression of p38 MAPK and JNK via Akt-mediated Inhibition of Apoptosis Signal-regulating Kinase 1 Constitutes a Core Component of the β-Cell Pro-survival Effects of Glucose-dependent Insulinotropic Polypeptide

(2009) Scott B. Widenmaier et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The core gut microbiome, energy balance and obesity

(2009) Peter J. Turnbaugh et al.   JOURNAL OF PHYSIOLOGY-LONDON

IL1β- and LPS-induced serotonin secretion is increased in EC cells derived from Crohn’s disease

(2009) m. kidd et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Effect of Ileal Infusion of Short-Chain Fatty Acids on Pancreatic Prandial Secretion and Gastrointestinal Hormones in Pigs

(2009) Vaida Sileikiene et al.   PANCREAS

Inhibition of histone-deacetylase activity by short-chain fatty acids and some polyphenol metabolites formed in the colon

(2008) Markus Waldecker et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

A core gut microbiome in obese and lean twins

(2008) Peter J. Turnbaugh et al.   NATURE

Mechanisms of action of CCK to activate central vagal afferent terminals

(2008) Richard C. Rogers et al.   PEPTIDES

Functional and comparative metagenomic analysis of bile salt hydrolase activity in the human gut microbiome

(2008) B. V. Jones et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA