Isoflurane Post-conditioning Ameliorates Cerebral Ischemia/Reperfusion Injury by Enhancing Angiogenesis Through Activating the Shh/Gli Signaling Pathway in Rats

Isoflurane post-conditioning down-regulates expression of aquaporin 4 in rats with cerebral ischemia/reperfusion injury and is possibly related to bone morphogenetic protein 4/Smad1/5/8 signaling pathway

(2018) Min Yuan et al.   BIOMEDICINE & PHARMACOTHERAPY

Isoflurane preconditioning inhibits the effects of tissue-type plasminogen activator on brain endothelial cell in an in vitro model of ischemic stroke

(2017) So Yeong Cheon et al.   International Journal of Medical Sciences

Administration of sonic hedgehog protein induces angiogenesis and has therapeutic effects after stroke in rats

(2017) Sheng-cai Chen et al.   NEUROSCIENCE

The Function of SDF-1-CXCR4 Axis in SP Cells-Mediated Protective Role for Renal Ischemia/Reperfusion Injury by SHH/GLI1-ABCG2 Pathway

(2017) Guanqun Ge et al.   SHOCK

Poststroke Sonic Hedgehog Agonist Treatment Improves Functional Recovery by Enhancing Neurogenesis and Angiogenesis

(2017) Yongming Jin et al.   STROKE

Transforming growth-beta 1 contributes to isoflurane postconditioning against cerebral ischemia–reperfusion injury by regulating the c-Jun N-terminal kinase signaling pathway

(2016) Sheng Wang et al.   BIOMEDICINE & PHARMACOTHERAPY

Polydatin ameliorates renal ischemia/reperfusion injury by decreasing apoptosis and oxidative stress through activating sonic hedgehog signaling pathway

(2016) Qiu-hong Meng et al.   FOOD AND CHEMICAL TOXICOLOGY

Auricular vagus nerve stimulation promotes functional recovery and enhances the post-ischemic angiogenic response in an ischemia/reperfusion rat model

(2016) Ying Jiang et al.   NEUROCHEMISTRY INTERNATIONAL

Isoflurano fornece neuroproteção em lesão cerebral hipóxico‐isquêmica neonatal por inibição da apoptose

(2016) De‐An Zhao et al.   Revista Brasileira de Anestesiologia

Hedgehog signaling mediates woven bone formation and vascularization during stress fracture healing

(2015) Nikolas H. Kazmers et al.   BONE

Impact of isoflurane on malignant capability of ovarian cancer in vitro ‡

(2015) X. Luo et al.   BRITISH JOURNAL OF ANAESTHESIA

Poststroke Angiogenesis, Con: Dark Side of Angiogenesis

(2015) J. Adamczak et al.   STROKE

Cellular prion protein promotes post-ischemic neuronal survival, angioneurogenesis and enhances neural progenitor cell homing via proteasome inhibition

(2015) T R Doeppner et al.   Cell Death & Disease

Activation of Sonic hedgehog signaling in ventricular cardiomyocytes exerts cardioprotection against ischemia reperfusion injuries

(2015) Ludovit Paulis et al.   Scientific Reports

Sonic hedgehog gene therapy increases the ability of the dystrophic skeletal muscle to regenerate after injury

(2014) A Piccioni et al.   GENE THERAPY

Sonic hedgehog signaling in the postnatal brain

(2014) Arturo Álvarez-Buylla et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Concise Review: Evidence for CD34 as a Common Marker for Diverse Progenitors

(2014) Laura E. Sidney et al.   STEM CELLS

A Smoothened receptor agonist is neuroprotective and promotes regeneration after ischemic brain injury

(2014) O V Chechneva et al.   Cell Death & Disease

Hedgehog-Dependent Regulation of Angiogenesis and Myogenesis Is Impaired in Aged Mice

(2013) Marie-Ange Renault et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Vascular endothelial growth factors (VEGFs) and stroke

(2013) David A. Greenberg et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Anti-oxidative, anti-apoptotic, and pro-angiogenic effects mediate functional improvement by sonic hedgehog against focal cerebral ischemia in rats

(2013) Shiang-Suo Huang et al.   EXPERIMENTAL NEUROLOGY

The Sonic Hedgehog Pathway Mediates Brain Plasticity and Subsequent Functional Recovery After Bone Marrow Stromal Cell Treatment of Stroke in Mice

(2013) Xiaoshuang Ding et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Global and regional burden of stroke during 1990–2010: findings from the Global Burden of Disease Study 2010

(2013) Valery L Feigin et al.   LANCET

Astrocyte-Derived Sonic Hedgehog Contributes to Angiogenesis in Brain Microvascular Endothelial Cells via RhoA/ROCK Pathway After Oxygen–Glucose Deprivation

(2013) Quan-Wei He et al.   MOLECULAR NEUROBIOLOGY

Vascular remodeling after ischemic stroke: Mechanisms and therapeutic potentials

(2013) Jialing Liu et al.   PROGRESS IN NEUROBIOLOGY

Sonic Hedgehog Signaling Pathway Mediates Cerebrolysin-Improved Neurological Function After Stroke

(2013) Li Zhang et al.   STROKE

Isoflurane Attenuates Blood–Brain Barrier Disruption in Ipsilateral Hemisphere After Subarachnoid Hemorrhage in Mice

(2012) Orhan Altay et al.   STROKE

Cyclopamine Attenuates Acute Warm Ischemia Reperfusion Injury in Cholestatic Rat Liver: Hope for Marginal Livers

(2011) Akshay Pratap et al.   MOLECULAR PHARMACEUTICS

Pleiotropic Beneficial Effects of Sonic Hedgehog Gene Therapy in an Experimental Model of Peripheral Limb Ischemia

(2011) Mariangela Palladino et al.   MOLECULAR THERAPY

Ischemia and reperfusion—from mechanism to translation

(2011) Holger K Eltzschig et al.   NATURE MEDICINE

Intermittent Hypobaric Hypoxia Preconditioning Induced Brain Ischemic Tolerance by Up-Regulating Glial Glutamate Transporter-1 in Rats

(2011) Shu-Juan Gong et al.   NEUROCHEMICAL RESEARCH

Isoflurane postconditioning induces neuroprotection via Akt activation and attenuation of increased mitochondrial membrane permeability

(2011) L. Li et al.   NEUROSCIENCE

The Hedgehog Pathway Promotes Blood-Brain Barrier Integrity and CNS Immune Quiescence

(2011) J. I. Alvarez et al.   SCIENCE

Magnetic resonance imaging of brain angiogenesis after stroke

(2010) Peter R. Seevinck et al.   ANGIOGENESIS

Hedgehog proteins activate pro-angiogenic responses in endothelial cells through non-canonical signaling pathways

(2010) Pilar Chinchilla et al.   CELL CYCLE

Hedgehog: functions and mechanisms

(2008) M. Varjosalo et al.   GENES & DEVELOPMENT