Astrocyte-Derived Sonic Hedgehog Contributes to Angiogenesis in Brain Microvascular Endothelial Cells via RhoA/ROCK Pathway After Oxygen–Glucose Deprivation

Neurovascular Unit: a Focus on Pericytes

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The protective effect of sonic hedgehog is mediated by the propidium iodide 3-kinase/AKT/Bcl-2 pathway in cultured rat astrocytes under oxidative stress

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The astrocyte-expressed integrin  v 8 governs blood vessel sprouting in the developing retina

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Integrin-dependent and -independent functions of astrocytic fibronectin in retinal angiogenesis

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The VEGF/Rho GTPase signalling pathway: A promising target for anti-angiogenic/anti-invasion therapy

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Heterotrimeric GiProteins Link Hedgehog Signaling to Activation of Rho Small GTPases to Promote Fibroblast Migration

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Signaling Pathways in Reactive Astrocytes, a Genetic Perspective

(2011) Wenfei Kang et al.   MOLECULAR NEUROBIOLOGY

Pleiotropic Beneficial Effects of Sonic Hedgehog Gene Therapy in an Experimental Model of Peripheral Limb Ischemia

(2011) Mariangela Palladino et al.   MOLECULAR THERAPY

Rho-kinase inhibition ameliorates peritoneal fibrosis and angiogenesis in a rat model of peritoneal sclerosis

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Relationship Between Sonic Hedgehog Protein, Brain-Derived Neurotrophic Factor and Oxidative Stress in Autism Spectrum Disorders

(2011) Laila Y. Al-Ayadhi   NEUROCHEMICAL RESEARCH

Sonic Hedgehog Activates the GTPases Rac1 and RhoA in a Gli-Independent Manner Through Coupling of Smoothened to Gi Proteins

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HA1077, a Rho kinase inhibitor, suppresses glioma-induced angiogenesis by targeting the Rho-ROCK and the mitogen-activated protein kinase kinase/extracellular signal-regulated kinase (MEK/ERK) signal pathways

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Hedgehog proteins activate pro-angiogenic responses in endothelial cells through non-canonical signaling pathways

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Altered Fate of Subventricular Zone Progenitor Cells and Reduced Neurogenesis following Neonatal Stroke

(2010) Ruggero Spadafora et al.   DEVELOPMENTAL NEUROSCIENCE

RhoA/ROCK signaling is essential for multiple aspects of VEGF-mediated angiogenesis

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Activation of Erk by sonic hedgehog independent of canonical hedgehog signalling

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Sonic hedgehog induces angiogenesis via Rho kinase-dependent signaling in endothelial cells

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Sonic Hedgehog Protects Cortical Neurons Against Oxidative Stress

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Sonic Hedgehog Gene Delivery to the Rodent Heart Promotes Angiogenesis via iNOS/Netrin-1/PKC Pathway

(2010) Rafeeq P. H. Ahmed et al.   PLoS One

Astrocyte-Derived Vascular Endothelial Growth Factor Stabilizes Vessels in the Developing Retinal Vasculature

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Brain angiogenesis in developmental and pathological processes: neurovascular injury and angiogenic recovery after stroke

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Brain angiogenesis in developmental and pathological processes: regulation, molecular and cellular communication at the neurovascular interface

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Sonic Hedgehog Pathway Activation Is Induced by Acute Brain Injury and Regulated by Injury-Related Inflammation

(2009) N. M. Amankulor et al.   JOURNAL OF NEUROSCIENCE

Sonic Hedgehog Regulates Ischemia/Hypoxia-Induced Neural Progenitor Proliferation

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Hypoxia induces a hedgehog response mediated by HIF-1α

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