Biocompatibility Considerations in the Design of Graphene Biomedical Materials

Electrical Neural Stimulation and Simultaneous in Vivo Monitoring with Transparent Graphene Electrode Arrays Implanted in GCaMP6f Mice

(2018) Dong-Wook Park et al.   ACS Nano

Electroconductive Biohybrid Collagen/Pristine Graphene Composite Biomaterials with Enhanced Biological Activity

(2018) Alan J. Ryan et al.   ADVANCED MATERIALS

Single layer and few layer graphene are degraded by neutrophil myeloperoxidase

(2018) Rajendra Kurapati et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

When stem cells meet graphene: Opportunities and challenges in regenerative medicine

(2018) Kenry et al.   BIOMATERIALS

Nanomedicine safety in preclinical and clinical development: focus on idiosyncratic injection/infusion reactions

(2018) Seyed Moein Moghimi   DRUG DISCOVERY TODAY

Single-layer graphene modulates neuronal communication and augments membrane ion currents

(2018) Niccolò Paolo Pampaloni et al.   Nature Nanotechnology

Production of ready-to-use few-layer graphene in aqueous suspensions

(2018) Jose M González-Domínguez et al.   Nature Protocols

Effects of thermal treatment on the adhesion strength and osteoinductive activity of single-layer graphene sheets on titanium substrates

(2018) Ming Gu et al.   Scientific Reports

A blueprint for the synthesis and characterisation of thin graphene oxide with controlled lateral dimensions for biomedicine

(2018) Artur Filipe Rodrigues et al.   2D Materials

Immunological impact of graphene oxide sheets in the abdominal cavity is governed by surface reactivity

(2018) Artur Filipe Rodrigues et al.   ARCHIVES OF TOXICOLOGY

Graphene Family Materials in Bone Tissue Regeneration: Perspectives and Challenges

(2018) Xinting Cheng et al.   Nanoscale Research Letters

Safety Assessment of Graphene-Based Materials: Focus on Human Health and the Environment

(2018) Bengt Fadeel et al.   ACS Nano

High-resolution mapping of infraslow cortical brain activity enabled by graphene microtransistors

(2018) Eduard Masvidal-Codina et al.   NATURE MATERIALS

Innovative coating based on graphene and their decorated nanoparticles for medical stent applications

(2018) Amr M. ElSawy et al.   Materials Science & Engineering C-Materials for Biological Applications

Ultrafast Molecular Stitching of Graphene Films at the Ethanol/Water Interface for High Volumetric Capacitance

(2017) Gang Lian et al.   NANO LETTERS

Water-based and biocompatible 2D crystal inks for all-inkjet-printed heterostructures

(2017) Daryl McManus et al.   Nature Nanotechnology

Tunable sieving of ions using graphene oxide membranes

(2017) Jijo Abraham et al.   Nature Nanotechnology

Nanoparticles and innate immunity: new perspectives on host defence

(2017) Diana Boraschi et al.   SEMINARS IN IMMUNOLOGY

Biodegradation of Carbon Nanotubes, Graphene, and Their Derivatives

(2017) Ming Chen et al.   TRENDS IN BIOTECHNOLOGY

In situ click chemistry generation of cyclooxygenase-2 inhibitors

(2017) Atul Bhardwaj et al.   Nature Communications

Endotoxin Contamination in Nanomaterials Leads to the Misinterpretation of Immunosafety Results

(2017) Yang Li et al.   Frontiers in Immunology

Ultrafast epitaxial growth of metre-sized single-crystal graphene on industrial Cu foil

(2017) Xiaozhi Xu et al.   Science Bulletin

Culture Media Critically Influence Graphene Oxide Effects on Plasma Membranes

(2017) Cyrill Bussy et al.   Chem

Graphene oxide is degraded by neutrophils and the degradation products are non-genotoxic

(2017) Sourav P. Mukherjee et al.   Nanoscale

The Effects of Extensive Glomerular Filtration of Thin Graphene Oxide Sheets on Kidney Physiology

(2016) Dhifaf A. Jasim et al.   ACS Nano

Graphene-based materials for tissue engineering

(2016) Su Ryon Shin et al.   ADVANCED DRUG DELIVERY REVIEWS

Biomedical Uses for 2D Materials Beyond Graphene: Current Advances and Challenges Ahead

(2016) Rajendra Kurapati et al.   ADVANCED MATERIALS

White Graphene undergoes Peroxidase Degradation

(2016) Rajendra Kurapati et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Graphene materials as 2D non-viral gene transfer vector platforms

(2016) M Vincent et al.   GENE THERAPY

Assessing biocompatibility of graphene oxide-based nanocarriers: A review

(2016) Siaw Fui Kiew et al.   JOURNAL OF CONTROLLED RELEASE

Endotoxin contamination: a key element in the interpretation of nanosafety studies

(2016) Yang Li et al.   Nanomedicine

Biological interactions of carbon-based nanomaterials: From coronation to degradation

(2016) Kunal Bhattacharya et al.   Nanomedicine-Nanotechnology Biology and Medicine

Toxicity of graphene-family nanoparticles: a general review of the origins and mechanisms

(2016) Lingling Ou et al.   Particle and Fibre Toxicology

Synthesis of few-layered, high-purity graphene oxide sheets from different graphite sources for biology

(2016) Dhifaf A Jasim et al.   2D Materials

Preparation, Characterization, and Antibacterial Activity of Silver Nanoparticle-Decorated Graphene Oxide Nanocomposite

(2015) Wei Shao et al.   ACS Applied Materials & Interfaces

Amplified Photoacoustic Performance and Enhanced Photothermal Stability of Reduced Graphene Oxide Coated Gold Nanorods for Sensitive Photoacoustic Imaging

(2015) Hyungwon Moon et al.   ACS Nano

Three-Dimensional Printing of High-Content Graphene Scaffolds for Electronic and Biomedical Applications

(2015) Adam E. Jakus et al.   ACS Nano

Soft, Flexible Freestanding Neural Stimulation and Recording Electrodes Fabricated from Reduced Graphene Oxide

(2015) Nicholas V. Apollo et al.   ADVANCED FUNCTIONAL MATERIALS

Degradation-by-design: Surface modification with functional substrates that enhance the enzymatic degradation of carbon nanotubes

(2015) Adukamparai Rajukrishnan Sureshbabu et al.   BIOMATERIALS

Covalent conjugation of mechanically stiff graphene oxide flakes to three-dimensional collagen scaffolds for osteogenic differentiation of human mesenchymal stem cells

(2015) Seokyung Kang et al.   CARBON

Graphene-based materials for flexible supercapacitors

(2015) Yuanlong Shao et al.   CHEMICAL SOCIETY REVIEWS

Long-term implant fixation and stress-shielding in total hip replacement

(2015) D.R. Sumner   JOURNAL OF BIOMECHANICS

The current graphene safety landscape – a literature mining exercise

(2015) Cyrill Bussy et al.   Nanoscale

Science and technology roadmap for graphene, related two-dimensional crystals, and hybrid systems

(2015) Andrea C. Ferrari et al.   Nanoscale

Tissue distribution and urinary excretion of intravenously administered chemically functionalized graphene oxide sheets

(2015) Dhifaf A. Jasim et al.   Chemical Science

A Systematic Review of Systemic Cobaltism After Wear or Corrosion of Chrome-Cobalt Hip Implants

(2015) Bradford D. Gessner et al.   Journal of Patient Safety

Multiscale, Hierarchically Patterned Topography for Directing Human Neural Stem Cells into Functional Neurons

(2014) Kisuk Yang et al.   ACS Nano

Guiding Stem Cell Differentiation into Oligodendrocytes Using Graphene-Nanofiber Hybrid Scaffolds

(2014) Shreyas Shah et al.   ADVANCED MATERIALS

Classification Framework for Graphene-Based Materials

(2014) Peter Wick et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Anti-inflammatory effects of three-dimensional graphene foams cultured with microglial cells

(2014) Qin Song et al.   BIOMATERIALS

Graphene for multi-functional synthetic biology: The last ‘zeitgeist’ in nanomedicine

(2014) A. Servant et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Harnessing the chemistry of graphene oxide

(2014) Daniel R. Dreyer et al.   CHEMICAL SOCIETY REVIEWS

Materials as stem cell regulators

(2014) William L. Murphy et al.   NATURE MATERIALS

Graphene devices for life

(2014) Kostas Kostarelos et al.   Nature Nanotechnology

Challenges and opportunities in graphene commercialization

(2014) Amaia Zurutuza et al.   Nature Nanotechnology

Exploring the Interface of Graphene and Biology

(2014) K. Kostarelos et al.   SCIENCE

Metal-Etching-Free Direct Delamination and Transfer of Single-Layer Graphene with a High Degree of Freedom

(2014) Sang Yoon Yang et al.   Small

Graphene-based carbon-layered electrode array technology for neural imaging and optogenetic applications

(2014) Dong-Wook Park et al.   Nature Communications

Graphene-Based Electroresponsive Scaffolds as Polymeric Implants for On-Demand Drug Delivery

(2014) Ania Servant et al.   Advanced Healthcare Materials

Graphene-Based Photothermal Agent for Rapid and Effective Killing of Bacteria

(2013) Meng-Chin Wu et al.   ACS Nano

Graphene and graphene oxide as new nanocarriers for drug delivery applications

(2013) Jingquan Liu et al.   Acta Biomaterialia

Prospects and Challenges of Graphene in Biomedical Applications

(2013) Dimitrios Bitounis et al.   ADVANCED MATERIALS

Graphene Oxide Nanoribbons from the Oxidative Opening of Carbon Nanotubes Retain Electrochemically Active Metallic Impurities

(2013) Colin Hong An Wong et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Graphene: Safe or Toxic? The Two Faces of the Medal

(2013) Alberto Bianco   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

All in the graphene family – A recommended nomenclature for two-dimensional carbon materials

(2013) Alberto Bianco et al.   CARBON

Accelerated differentiation of neural stem cells into neurons on ginseng-reduced graphene oxide sheets

(2013) Omid Akhavan et al.   CARBON

Graphene-based nanomaterials for drug delivery and tissue engineering

(2013) Sumit Goenka et al.   JOURNAL OF CONTROLLED RELEASE

Three-dimensional graphene foams promote osteogenic differentiation of human mesenchymal stem cells

(2013) Spencer W. Crowder et al.   Nanoscale

Three-dimensional graphene foam as a biocompatible and conductive scaffold for neural stem cells

(2013) Ning Li et al.   Scientific Reports

Confocal Raman Imaging Study Showing Macrophage Mediated Biodegradation of Graphene In Vivo

(2013) Chundayil Madathil Girish et al.   Advanced Healthcare Materials

Safety Considerations for Graphene: Lessons Learnt from Carbon Nanotubes

(2012) Cyrill Bussy et al.   ACCOUNTS OF CHEMICAL RESEARCH

Ultrasmall Gold Nanoparticles Anchored to Graphene and Enhanced Photothermal Effects by Laser Irradiation of Gold Nanostructures in Graphene Oxide Solutions

(2012) Abdallah F. Zedan et al.   ACS Nano

Photoluminescent Graphene Oxide Ink to Print Sensors onto Microporous Membranes for Versatile Visualization Bioassays

(2012) Qingsong Mei et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The role of the lateral dimension of graphene oxide in the regulation of cellular responses

(2012) Hua Yue et al.   BIOMATERIALS

Graphene Oxide Wrapping on Squaraine-Loaded Mesoporous Silica Nanoparticles for Bioimaging

(2012) Sivaramapanicker Sreejith et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A roadmap for graphene

(2012) K. S. Novoselov et al.   NATURE

Edge-carboxylated graphene nanosheets via ball milling

(2012) I.-Y. Jeon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Laser Scribing of High-Performance and Flexible Graphene-Based Electrochemical Capacitors

(2012) M. F. El-Kady et al.   SCIENCE

Purified Graphene Oxide Dispersions Lack In Vitro Cytotoxicity and In Vivo Pathogenicity

(2012) Hanene Ali-Boucetta et al.   Advanced Healthcare Materials

Origin of Enhanced Stem Cell Growth and Differentiation on Graphene and Graphene Oxide

(2011) Wong Cheng Lee et al.   ACS Nano

Graphene-Based Nanoplatelets: A New Risk to the Respiratory System as a Consequence of Their Unusual Aerodynamic Properties

(2011) Anja Schinwald et al.   ACS Nano

Regulating Cellular Behavior on Few-Layer Reduced Graphene Oxide Films with Well-Controlled Reduction States

(2011) Xuetao Shi et al.   ADVANCED FUNCTIONAL MATERIALS

A graphene-based platform for induced pluripotent stem cells culture and differentiation

(2011) G.-Y. Chen et al.   BIOMATERIALS

In vitro and in vivo behaviors of dextran functionalized graphene

(2011) Shuai Zhang et al.   CARBON

The reduction of graphene oxide

(2011) Songfeng Pei et al.   CARBON

Electrospun conducting polymer nanofibers and electrical stimulation of nerve stem cells

(2011) Molamma P. Prabhakaran et al.   JOURNAL OF BIOSCIENCE AND BIOENGINEERING

Adverse reaction to metal debris following hip resurfacing

(2011) D. J. Langton et al.   JOURNAL OF BONE AND JOINT SURGERY-BRITISH VOLUME

The Role of Oxygen during Thermal Reduction of Graphene Oxide Studied by Infrared Absorption Spectroscopy

(2011) Muge Acik et al.   Journal of Physical Chemistry C

Probing the Thermal Deoxygenation of Graphene Oxide Using High-Resolution In Situ X-ray-Based Spectroscopies

(2011) Abhijit Ganguly et al.   Journal of Physical Chemistry C

Steam Etched Porous Graphene Oxide Network for Chemical Sensing

(2011) Tae Hee Han et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Minimizing Oxidation and Stable Nanoscale Dispersion Improves the Biocompatibility of Graphene in the Lung

(2011) Matthew C. Duch et al.   NANO LETTERS

Three-dimensional flexible and conductive interconnected graphene networks grown by chemical vapour deposition

(2011) Zongping Chen et al.   NATURE MATERIALS

Highly Wrinkled Cross-Linked Graphene Oxide Membranes for Biological and Charge-Storage Applications

(2011) Lena A. L. Tang et al.   Small

The Biocompatibility Manifesto: Biocompatibility for the Twenty-first Century

(2011) Buddy D. Ratner   Journal of Cardiovascular Translational Research

Cytotoxicity Effects of Graphene and Single-Wall Carbon Nanotubes in Neural Phaeochromocytoma-Derived PC12 Cells

(2010) Yongbin Zhang et al.   ACS Nano

Graphene-Based Antibacterial Paper

(2010) Wenbing Hu et al.   ACS Nano

Improved Synthesis of Graphene Oxide

(2010) Daniela C. Marcano et al.   ACS Nano

Direct reduction of graphene oxide films into highly conductive and flexible graphene films by hydrohalic acids

(2010) Songfeng Pei et al.   CARBON

Distribution and biocompatibility studies of graphene oxide in mice after intravenous administration

(2010) Xiaoyong Zhang et al.   CARBON

Structural evolution during the reduction of chemically derived graphene oxide

(2010) Akbar Bagri et al.   Nature Chemistry

Low-Temperature Exfoliated Graphenes: Vacuum-Promoted Exfoliation and Electrochemical Energy Storage

(2009) Wei Lv et al.   ACS Nano

Electrochemical Sensing and Biosensing Platform Based on Chemically Reduced Graphene Oxide

(2009) Ming Zhou et al.   ANALYTICAL CHEMISTRY

Reduction of graphene oxide vial-ascorbic acid

(2009) Jiali Zhang et al.   CHEMICAL COMMUNICATIONS

Hydrothermal Dehydration for the “Green” Reduction of Exfoliated Graphene Oxide to Graphene and Demonstration of Tunable Optical Limiting Properties

(2009) Yong Zhou et al.   CHEMISTRY OF MATERIALS

Large-scale pattern growth of graphene films for stretchable transparent electrodes

(2009) Keun Soo Kim et al.   NATURE

The electronic properties of graphene

(2009) A. H. Castro Neto et al.   REVIEWS OF MODERN PHYSICS

Large-Area Synthesis of High-Quality and Uniform Graphene Films on Copper Foils

(2009) X. Li et al.   SCIENCE

On the mechanisms of biocompatibility

(2008) David F. Williams   BIOMATERIALS

Chemical analysis of graphene oxide films after heat and chemical treatments by X-ray photoelectron and Micro-Raman spectroscopy

(2008) Dongxing Yang et al.   CARBON

Biomaterials engineered for integration

(2008) Lorenzo Moroni et al.   Materials Today

Large Area, Few-Layer Graphene Films on Arbitrary Substrates by Chemical Vapor Deposition

(2008) Alfonso Reina et al.   NANO LETTERS

Large-area ultrathin films of reduced graphene oxide as a transparent and flexible electronic material

(2008) Goki Eda et al.   Nature Nanotechnology

High-yield production of graphene by liquid-phase exfoliation of graphite

(2008) Yenny Hernandez et al.   Nature Nanotechnology