Graphene: Safe or Toxic? The Two Faces of the Medal

Biomimetic Peptide Nanosensors

(2012) Yue Cui et al.   ACCOUNTS OF CHEMICAL RESEARCH

Safety Considerations for Graphene: Lessons Learnt from Carbon Nanotubes

(2012) Cyrill Bussy et al.   ACCOUNTS OF CHEMICAL RESEARCH

Size-Dependent Cell Uptake of Protein-Coated Graphene Oxide Nanosheets

(2012) Qingxin Mu et al.   ACS Applied Materials & Interfaces

Amine-Modified Graphene: Thrombo-Protective Safer Alternative to Graphene Oxide for Biomedical Applications

(2012) Sunil K. Singh et al.   ACS Nano

Unraveling Stress-Induced Toxicity Properties of Graphene Oxide and the Underlying Mechanism

(2012) Wendi Zhang et al.   ADVANCED MATERIALS

The role of the lateral dimension of graphene oxide in the regulation of cellular responses

(2012) Hua Yue et al.   BIOMATERIALS

Translocation mechanisms of chemically functionalised carbon nanotubes across plasma membranes

(2012) Lara Lacerda et al.   BIOMATERIALS

Simultaneous induction of autophagy and toll-like receptor signaling pathways by graphene oxide

(2012) Guan-Yu Chen et al.   BIOMATERIALS

Graphene quantum dots as autophagy-inducing photodynamic agents

(2012) Zoran M. Markovic et al.   BIOMATERIALS

The effects of graphene oxide nanosheets localized on F-actin filaments on cell-cycle alterations

(2012) María-Concepción Matesanz et al.   BIOMATERIALS

Cell specific cytotoxicity and uptake of graphene nanoribbons

(2012) Sayan Mullick Chowdhury et al.   BIOMATERIALS

The use of polyethyleneimine-modified reduced graphene oxide as a substrate for silver nanoparticles to produce a material with lower cytotoxicity and long-term antibacterial activity

(2012) Xiang Cai et al.   CARBON

Synthesis and antifungal activity of reduced graphene oxide nanosheets

(2012) Montree Sawangphruk et al.   CARBON

A stimuli-sensitive injectable graphene oxide composite hydrogel

(2012) Abhishek Sahu et al.   CHEMICAL COMMUNICATIONS

Can Graphene Oxide Cause Damage to Eyesight?

(2012) Lu Yan et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Nano-graphene in biomedicine: theranostic applications

(2012) Kai Yang et al.   CHEMICAL SOCIETY REVIEWS

Recent advances in graphene family materials toxicity investigations

(2012) Agnieszka Maria Jastrzębska et al.   JOURNAL OF NANOPARTICLE RESEARCH

Pristine Graphite Oxide

(2012) Ayrat Dimiev et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Lateral Dimension-Dependent Antibacterial Activity of Graphene Oxide Sheets

(2012) Shaobin Liu et al.   LANGMUIR

Graphite Nanoplatelets and Caenorhabditis elegans: Insights from an in Vivo Model

(2012) Elena Zanni et al.   NANO LETTERS

Effect of size and dose on the biodistribution of graphene oxide in mice

(2012) Jia-Hui Liu et al.   Nanomedicine

Effect of graphene oxide on undifferentiated and retinoic acid-differentiated SH-SY5Y cells line

(2012) Min Lv et al.   Nanoscale

Graphene: a versatile nanoplatform for biomedical applications

(2012) Yin Zhang et al.   Nanoscale

Toxicity of a polymer–graphene oxide composite against bacterial planktonic cells, biofilms, and mammalian cells

(2012) Isis E. Mejías Carpio et al.   Nanoscale

Graphene nanocomposite for biomedical applications: fabrication, antimicrobial and cytotoxic investigations

(2012) Catherine M Santos et al.   NANOTECHNOLOGY

A roadmap for graphene

(2012) K. S. Novoselov et al.   NATURE

Biodegradable nanocomposites of amyloid fibrils and graphene with shape-memory and enzyme-sensing properties

(2012) Chaoxu Li et al.   Nature Nanotechnology

Hemocompatibility and Macrophage Response of Pristine and Functionalized Graphene

(2012) Abhilash Sasidharan et al.   Small

Biomedical Applications of Graphene

(2012) He Shen et al.   Theranostics

Cytotoxicity of Graphene Oxide and Graphene in Human Erythrocytes and Skin Fibroblasts

(2011) Ken-Hsuan Liao et al.   ACS Applied Materials & Interfaces

Graphene Oxide: A Nonspecific Enhancer of Cellular Growth

(2011) Oscar N. Ruiz et al.   ACS Nano

The Enzymatic Oxidation of Graphene Oxide

(2011) Gregg P. Kotchey et al.   ACS Nano

Thrombus Inducing Property of Atomically Thin Graphene Oxide Sheets

(2011) Sunil K. Singh et al.   ACS Nano

Antibacterial Activity of Graphite, Graphite Oxide, Graphene Oxide, and Reduced Graphene Oxide: Membrane and Oxidative Stress

(2011) Shaobin Liu et al.   ACS Nano

Graphene-Based Nanoplatelets: A New Risk to the Respiratory System as a Consequence of Their Unusual Aerodynamic Properties

(2011) Anja Schinwald et al.   ACS Nano

Length-Dependent Retention of Carbon Nanotubes in the Pleural Space of Mice Initiates Sustained Inflammation and Progressive Fibrosis on the Parietal Pleura

(2011) Fiona A. Murphy et al.   AMERICAN JOURNAL OF PATHOLOGY

The triggering of apoptosis in macrophages by pristine graphene through the MAPK and TGF-beta signaling pathways

(2011) Yang Li et al.   BIOMATERIALS

In vitro and in vivo behaviors of dextran functionalized graphene

(2011) Shuai Zhang et al.   CARBON

Escherichia coli bacteria reduce graphene oxide to bactericidal graphene in a self-limiting manner

(2011) O. Akhavan et al.   CARBON

Biological Interactions of Graphene-Family Nanomaterials: An Interdisciplinary Review

(2011) Vanesa C. Sanchez et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Graphene-based composites

(2011) Xiao Huang et al.   CHEMICAL SOCIETY REVIEWS

Synthesis, dispersion, and cytocompatibility of graphene oxide and reduced graphene oxide

(2011) Malgorzata Wojtoniszak et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Toxicity of Graphene in Normal Human Lung Cells (BEAS-2B)

(2011) N. V. Srikanth Vallabani et al.   Journal of Biomedical Nanotechnology

Minimizing Oxidation and Stable Nanoscale Dispersion Improves the Biocompatibility of Graphene in the Lung

(2011) Matthew C. Duch et al.   NANO LETTERS

Graphene in biomedicine: opportunities and challenges

(2011) Liangzhu Feng et al.   Nanomedicine

Differential nano-bio interactions and toxicity effects of pristine versus functionalized graphene

(2011) Abhilash Sasidharan et al.   Nanoscale

Graphene-Based Materials: Synthesis, Characterization, Properties, and Applications

(2011) Xiao Huang et al.   Small

Cytotoxicity Evaluation of Oxidized Single-Walled Carbon Nanotubes and Graphene Oxide on Human Hepatoma HepG2 cells: An iTRAQ-Coupled 2D LC-MS/MS Proteome Analysis

(2011) Jifeng Yuan et al.   TOXICOLOGICAL SCIENCES

Comparative protein profile of human hepatoma HepG2 cells treated with graphene and single-walled carbon nanotubes: An iTRAQ-coupled 2D LC–MS/MS proteome analysis

(2011) Jifeng Yuan et al.   TOXICOLOGY LETTERS

Cytotoxicity Effects of Graphene and Single-Wall Carbon Nanotubes in Neural Phaeochromocytoma-Derived PC12 Cells

(2010) Yongbin Zhang et al.   ACS Nano

In Vivo Pharmacokinetics, Long-Term Biodistribution, and Toxicology of PEGylated Graphene in Mice

(2010) Kai Yang et al.   ACS Nano

Graphene-Based Antibacterial Paper

(2010) Wenbing Hu et al.   ACS Nano

Toxicity of Graphene and Graphene Oxide Nanowalls Against Bacteria

(2010) Omid Akhavan et al.   ACS Nano

Distribution and biocompatibility studies of graphene oxide in mice after intravenous administration

(2010) Xiaoyong Zhang et al.   CARBON

The chemistry of graphene

(2010) Kian Ping Loh et al.   JOURNAL OF MATERIALS CHEMISTRY

Graphene in Mice: Ultrahigh In Vivo Tumor Uptake and Efficient Photothermal Therapy

(2010) Kai Yang et al.   NANO LETTERS

Low-toxic and safe nanomaterials by surface-chemical design, carbon nanotubes, fullerenes, metallofullerenes, and graphenes

(2010) Liang Yan et al.   Nanoscale

Graphene oxide as a chemically tunable platform for optical applications

(2010) Kian Ping Loh et al.   Nature Chemistry

In vitro toxicity evaluation of graphene oxide on A549 cells

(2010) Yanli Chang et al.   TOXICOLOGY LETTERS

Sandwiched Graphene−Membrane Superstructures

(2009) Alexey V. Titov et al.   ACS Nano

Flash Reduction and Patterning of Graphite Oxide and Its Polymer Composite

(2009) Laura J. Cote et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Promises, facts and challenges for carbon nanotubes in imaging and therapeutics

(2009) K. Kostarelos et al.   Nature Nanotechnology

PEGylated Nanographene Oxide for Delivery of Water-Insoluble Cancer Drugs

(2008) Zhuang Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nano-graphene oxide for cellular imaging and drug delivery

(2008) Xiaoming Sun et al.   Nano Research

The long and short of carbon nanotube toxicity

(2008) Kostas Kostarelos   NATURE BIOTECHNOLOGY

Carbon nanotubes introduced into the abdominal cavity of mice show asbestos-like pathogenicity in a pilot study

(2008) Craig A. Poland et al.   Nature Nanotechnology