Endotoxin contamination: a key element in the interpretation of nanosafety studies

Size Effects of Nanomaterials on Lung Inflammation and Coagulatory Disturbance

(2017) K. Inoue et al.   INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY

The NLRP3 inflammasome is activated by nanoparticles through ATP, ADP and adenosine

(2015) L Baron et al.   Cell Death & Disease

Gel filtration chromatography as a method for removing bacterial endotoxin from antibody preparations

(2014) Anne Serdakowski London et al.   BIOTECHNOLOGY PROGRESS

Inflammasome Priming by Lipopolysaccharide Is Dependent upon ERK Signaling and Proteasome Function

(2014) M. G. Ghonime et al.   JOURNAL OF IMMUNOLOGY

Challenges facing sterilization and depyrogenation of nanoparticles: Effects on structural stability and biomedical applications

(2014) Melissa A. Vetten et al.   Nanomedicine-Nanotechnology Biology and Medicine

Optimising the use of commercial LAL assays for the analysis of endotoxin contamination in metal colloids and metal oxide nanoparticles

(2014) Yang Li et al.   Nanotoxicology

Polyhydroxylated Metallofullerenols Stimulate IL-1β Secretion of Macrophage through TLRs/MyD88/NF-κB Pathway and NLRP3Inflammasome Activation

(2014) Zhiyun Chen et al.   Small

Toll-Like Receptor 4 is Involved in Titanium Dioxide Nanoparticle Incorporation Into Cells

(2014) Sharmy Saimon Mano et al.   Science of Advanced Materials

Mimicking exposures to acute and lifetime concentrations of inhaled silver nanoparticles by two different in vitro approaches

(2014) Fabian Herzog et al.   Beilstein Journal of Nanotechnology

Graphene Oxide Induces Toll-like Receptor 4 (TLR4)-Dependent Necrosis in Macrophages

(2013) Guangbo Qu et al.   ACS Nano

Interference of silica nanoparticles with the traditional Limulus amebocyte lysate gel clot assay

(2013) Melanie Kucki et al.   Innate Immunity

Comparison of Cellular Uptake and Inflammatory Response via Toll-Like Receptor 4 to Lipopolysaccharide and Titanium Dioxide Nanoparticles

(2013) Sharmy Mano et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Cutting Edge: TLR Signaling Licenses IRAK1 for Rapid Activation of the NLRP3 Inflammasome

(2013) T. Fernandes-Alnemri et al.   JOURNAL OF IMMUNOLOGY

Synthetic Ligand-Coated Magnetic Nanoparticles for Microfluidic Bacterial Separation from Blood

(2013) Jung-Jae Lee et al.   NANO LETTERS

Choice of method for endotoxin detection depends on nanoformulation

(2013) Marina A Dobrovolskaia et al.   Nanomedicine

Endotoxins—the Invisible Companion in Biomaterials Research

(2013) Ramona Lieder et al.   TISSUE ENGINEERING PART B-REVIEWS

Simultaneous induction of autophagy and toll-like receptor signaling pathways by graphene oxide

(2012) Guan-Yu Chen et al.   BIOMATERIALS

Endotoxin removal and prevention for pre-clinical biologics production

(2012) Anne Serdakowski London et al.   Biotechnology Journal

Effect of Al2O3 nanoparticles on bacterial membrane amphiphilic biomolecules

(2012) Wei Jiang et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

The anti-inflammatory effects of platinum nanoparticles on the lipopolysaccharide-induced inflammatory response in RAW 264.7 macrophages

(2012) Mati Ur Rehman et al.   INFLAMMATION RESEARCH

Non-transcriptional Priming and Deubiquitination Regulate NLRP3 Inflammasome Activation

(2012) Christine Juliana et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Enhancement of lipopolysaccharide-induced nitric oxide and interleukin-6 production by PEGylated gold nanoparticles in RAW264.7 cells

(2012) Zhimin Liu et al.   Nanoscale

Contamination of nanoparticles by endotoxin: evaluation of different test methods

(2012) Stijn Smulders et al.   Particle and Fibre Toxicology

Endotoxin Removal by Magnetic Separation-Based Blood Purification

(2012) Inge K. Herrmann et al.   Advanced Healthcare Materials

Extracellular Histones Are Mediators of Death through TLR2 and TLR4 in Mouse Fatal Liver Injury

(2011) J. Xu et al.   JOURNAL OF IMMUNOLOGY

Towards nanotechnology regulation – Publish the unpublishable

(2011) Steve Hankin et al.   Nano Today

Problems and challenges in the development and validation of human cell-based assays to determine nanoparticle-induced immunomodulatory effects

(2011) Gertie J. Oostingh et al.   Particle and Fibre Toxicology

Inflammasome activation and IL-1β and IL-18 processing during infection

(2011) Frank L. van de Veerdonk et al.   TRENDS IN IMMUNOLOGY

Signaling pathway of inflammatory responses in the mouse liver caused by TiO2 nanoparticles

(2010) Yaling Cui et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Endotoxin Promotes Adverse Effects of Amorphous Silica Nanoparticles on Lung Epithelial Cells in Vitro

(2010) Yongli Shi et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES

Binding of Functionalized Paramagnetic Nanoparticles to Bacterial Lipopolysaccharides And DNA

(2010) Lev Bromberg et al.   LANGMUIR

Ambiguities in applying traditionalLimulusAmebocyte Lysate tests to quantify endotoxin in nanoparticle formulations

(2010) Marina A Dobrovolskaia et al.   Nanomedicine

Endotoxin contamination of engineered nanomaterials

(2010) R. Keith Esch et al.   Nanotoxicology

Gold nanoparticles attenuate LPS-induced NO production through the inhibition of NF-κB and IFN-β/STAT1 pathways in RAW264.7 cells

(2010) Ji Su Ma et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Impact of agglomeration state of nano- and submicron sized gold particles on pulmonary inflammation

(2010) Ilse Gosens et al.   Particle and Fibre Toxicology

Nanoparticles activate the NLR pyrin domain containing 3 (Nlrp3) inflammasome and cause pulmonary inflammation through release of IL-1  and IL-1 

(2010) A. S. Yazdi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

In vitro assessments of nanomaterial toxicity

(2009) Clinton F. Jones et al.   ADVANCED DRUG DELIVERY REVIEWS

Minireview: Nanoparticles and the Immune System

(2009) Banu S. Zolnik et al.   ENDOCRINOLOGY

Evaluation of nanoparticle immunotoxicity

(2009) Marina A. Dobrovolskaia et al.   Nature Nanotechnology

Low pressure plasma discharges for the sterilization and decontamination of surfaces

(2009) F Rossi et al.   NEW JOURNAL OF PHYSICS

Sterilization Matters: Consequences of Different Sterilization Techniques on Gold Nanoparticles

(2009) Ángela França et al.   Small

Oxidative stress and proinflammatory effects of carbon black and titanium dioxide nanoparticles: Role of particle surface area and internalized amount

(2009) Salik Hussain et al.   TOXICOLOGY

LPS/TLR4 signal transduction pathway

(2008) Yong-Chen Lu et al.   CYTOKINE

Effects of Pulmonary Exposure to Carbon Nanotubes on Lung and Systemic Inflammation with Coagulatory Disturbance Induced by Lipopolysaccharide in Mice

(2008) Ken-ichiro Inoue et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Removal of immune-stimulatory components from surfaces by plasma discharges

(2008) Marina Hasiwa et al.   Innate Immunity

Peptides conjugated to gold nanoparticles induce macrophage activation

(2008) Neus G. Bastús et al.   MOLECULAR IMMUNOLOGY

Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

(2008) Veit Hornung et al.   NATURE IMMUNOLOGY

Innate Immune Activation Through Nalp3 Inflammasome Sensing of Asbestos and Silica

(2008) C. Dostert et al.   SCIENCE

Size effects of latex nanomaterials on lung inflammation in mice

(2008) Ken-ichiro Inoue et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Endotoxin Limits in Formulations for Preclinical Research

(2007) Padma Malyala et al.   JOURNAL OF PHARMACEUTICAL SCIENCES