Transcriptional control of apoptotic cell clearance by macrophage nuclear receptors

Adenosine produced from adenine nucleotides through an interaction between apoptotic cells and engulfing macrophages contributes to the appearance of transglutaminase 2 in dying thymocytes

(2016) Katalin Sándor et al.   AMINO ACIDS

The Gas6-Axl Protein Interaction Mediates Endothelial Uptake of Platelet Microparticles

(2016) Kaisa E. Happonen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human Peripheral Blood Mononuclear Cell Function and Dendritic Cell Differentiation Are Affected by Bisphenol-A Exposure

(2016) Alessandra Camarca et al.   PLoS One

Transglutaminase 2 interacts with syndecan-4 and CD44 at the surface of human macrophages to promote removal of apoptotic cells

(2015) Vinod Nadella et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Glucocorticoids enhance prolonged clearance of apoptotic cells by upregulating liver X receptor, peroxisome proliferator-activated receptor-δ and UCP2

(2015) Éva Garabuczi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Apoptotic cell recognition receptors and scavenger receptors

(2015) Kristen K. Penberthy et al.   IMMUNOLOGICAL REVIEWS

Apoptotic cells trigger a membrane-initiated pathway to increase ABCA1

(2015) Aaron M. Fond et al.   JOURNAL OF CLINICAL INVESTIGATION

Retinoid X receptors orchestrate osteoclast differentiation and postnatal bone remodeling

(2015) María P. Menéndez-Gutiérrez et al.   JOURNAL OF CLINICAL INVESTIGATION

The PPAR-γ antagonist GW9662 elicits differentiation of M2c-like cells and upregulation of the MerTK/Gas6 axis: a key role for PPAR-γ in human macrophage polarization

(2015) Gaetano Zizzo et al.   Journal of Inflammation-London

Nuclear Receptors License Phagocytosis by Trem2+ Myeloid Cells in Mouse Models of Alzheimer's Disease

(2015) J. C. Savage et al.   JOURNAL OF NEUROSCIENCE

Understanding the Mysterious M2 Macrophage through Activation Markers and Effector Mechanisms

(2015) Tamás Rőszer   MEDIATORS OF INFLAMMATION

PPARγ activation following apoptotic cell instillation promotes resolution of lung inflammation and fibrosis via regulation of efferocytosis and proresolving cytokines

(2015) Y-S Yoon et al.   Mucosal Immunology

Effects of Endocrine Disruptor Compounds, Alone or in Combination, on Human Macrophage-Like THP-1 Cell Response

(2015) N. Couleau et al.   PLoS One

Mer signaling increases the abundance of the transcription factor LXR to promote the resolution of acute sterile inflammation

(2015) Ji-Yeon Choi et al.   Science Signaling

Mer receptor tyrosine kinase mediates both tethering and phagocytosis of apoptotic cells

(2015) I Dransfield et al.   Cell Death & Disease

Mer signaling increases the abundance of the transcription factor LXR to promote the resolution of acute sterile inflammation

(2015) Ji-Yeon Choi et al.   Science Signaling

Lipopolysaccharide-Stimulated Transglutaminase 2 Expression Enhances Endocytosis Activity in the Mouse Microglial Cell Line BV-2

(2015) Kenji Kawabe et al.   NEUROIMMUNOMODULATION

Mertk Deficiency Affects Macrophage Directional Migration via Disruption of Cytoskeletal Organization

(2015) Yong Tang et al.   PLoS One

What We Talk About When We Talk About Fat

(2014) Evan D. Rosen et al.   CELL

Embryonic and Adult-Derived Resident Cardiac Macrophages Are Maintained through Distinct Mechanisms at Steady State and during Inflammation

(2014) Slava Epelman et al.   IMMUNITY

Macrophages Engulfing Apoptotic Cells Produce Nonclassical Retinoids To Enhance Their Phagocytic Capacity

(2014) Z. Sarang et al.   JOURNAL OF IMMUNOLOGY

Complement, C1q, and C1q-Related Molecules Regulate Macrophage Polarization

(2014) Suzanne S. Bohlson et al.   Frontiers in Immunology

Macrophages engulfing apoptotic thymocytes produce retinoids to promote selection, differentiation, removal and replacement of double positive thymocytes

(2013) Zsolt Sarang et al.   IMMUNOBIOLOGY

Retinoid X receptors in macrophage biology

(2013) Tamás Rőszer et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Molecular Mechanisms of Environmental Organotin Toxicity in Mammals

(2012) Yaichiro Kotake   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Inflammation and Lipid Signaling in the Etiology of Insulin Resistance

(2012) Christopher K. Glass et al.   Cell Metabolism

CED-1, CED-7, and TTR-52 Regulate Surface Phosphatidylserine Expression on Apoptotic and Phagocytic Cells

(2012) James Mapes et al.   CURRENT BIOLOGY

Biology and Therapeutic Applications of Peroxisome Proliferator- Activated Receptors

(2012) Maria P. Menendez-Gutierrez et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Efficient Clearance of Early Apoptotic Cells by Human Macrophages Requires M2c Polarization and MerTK Induction

(2012) G. Zizzo et al.   JOURNAL OF IMMUNOLOGY

Retinoids produced by macrophages engulfing apoptotic cells contribute to the appearance of transglutaminase 2 in apoptotic thymocytes

(2011) Éva Garabuczi et al.   AMINO ACIDS

Erratum: Microparticles from apoptotic platelets promote resident macrophage differentiation

(2011) E M Vasina et al.   Cell Death & Disease

Autoimmune Kidney Disease and Impaired Engulfment of Apoptotic Cells in Mice with Macrophage Peroxisome Proliferator-Activated Receptor   or Retinoid X Receptor   Deficiency

(2010) T. Roszer et al.   JOURNAL OF IMMUNOLOGY

Inflammatory Mediators and Insulin Resistance in Obesity: Role of Nuclear Receptor Signaling in Macrophages

(2010) Lucía Fuentes et al.   MEDIATORS OF INFLAMMATION

Recent development of the mononuclear phagocyte system: in memory of Metchnikoff and Ehrlich on the 100th Anniversary of the 1908 Nobel Prize in Physiology or Medicine

(2009) Zong-Liang Chang   BIOLOGY OF THE CELL

Induction of Transglutaminase 2 by a Liver X Receptor/Retinoic Acid Receptor α Pathway Increases the Clearance of Apoptotic Cells by Human Macrophages

(2009) Cédric Rébé et al.   CIRCULATION RESEARCH

Activation of RXR–PPAR heterodimers by organotin environmental endocrine disruptors

(2009) Albane le Maire et al.   EMBO REPORTS

Apoptotic Cells Promote Their Own Clearance and Immune Tolerance through Activation of the Nuclear Receptor LXR

(2009) Noelia A-Gonzalez et al.   IMMUNITY

Transglutaminase 2 Is Needed for the Formation of an Efficient Phagocyte Portal in Macrophages Engulfing Apoptotic Cells

(2009) B. Toth et al.   JOURNAL OF IMMUNOLOGY

PPAR-mediated activity of phthalates: A link to the obesity epidemic?

(2009) Béatrice Desvergne et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Endocrine disrupters as obesogens

(2009) Felix Grün et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

PPAR-δ senses and orchestrates clearance of apoptotic cells to promote tolerance

(2009) Lata Mukundan et al.   NATURE MEDICINE

CD36, a Scavenger Receptor Involved in Immunity, Metabolism, Angiogenesis, and Behavior

(2009) R. L. Silverstein et al.   Science Signaling

Regulation of Macrophage Functions by PPAR-α, PPAR-γ, and LXRs in Mice and Men

(2008) Elena Rigamonti et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Role of complement and complement regulators in the removal of apoptotic cells

(2007) L.A. Trouw et al.   MOLECULAR IMMUNOLOGY