Inhibition of autophagy by chloroquine induces apoptosis in primary effusion lymphoma in vitro and in vivo through induction of endoplasmic reticulum stress

Autophagy in acute leukemias: A double-edged sword with important therapeutic implications

(2015) Cecilia Evangelisti et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Emerging strategies to effectively target autophagy in cancer

(2015) V W Rebecca et al.   ONCOGENE

Sorting, recognition and activation of the misfolded protein degradation pathways through macroautophagy and the proteasome

(2014) Wen-Xing Ding et al.   Autophagy

MiR-29b replacement inhibits proteasomes and disrupts aggresome+autophagosome formation to enhance the antimyeloma benefit of bortezomib

(2014) S Jagannathan et al.   LEUKEMIA

Chloroquine in Cancer Therapy: A Double-Edged Sword of Autophagy

(2013) T. Kimura et al.   CANCER RESEARCH

Establishment of a CD4-positive cell line from an AIDS-related primary effusion lymphoma

(2013) Hiroki Goto et al.   INTERNATIONAL JOURNAL OF HEMATOLOGY

Perturbation of proteasome function by bortezomib leading to ER stress-induced apoptotic cell death in cholangiocarcinoma

(2013) Kulthida Vaeteewoottacharn et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Inhibition of autophagy with chloroquine is effective in melanoma

(2013) Michael E. Egger et al.   JOURNAL OF SURGICAL RESEARCH

The anti-malarial chloroquine overcomes Primary resistance and restores sensitivity to Trastuzumab in HER2-positive breast cancer

(2013) Sílvia Cufí et al.   Scientific Reports

Chloroquine overcomes resistance of lung carcinoma cells to the dual PI3K/mTOR inhibitor PI103 by lysosome-mediated apoptosis

(2012) Stefanie Enzenmüller et al.   ANTI-CANCER DRUGS

New insights into mechanisms of therapeutic effects of antimalarial agents in SLE

(2012) Daniel J. Wallace et al.   Nature Reviews Rheumatology

Blocking Autophagy Prevents Bortezomib-Induced NF-κB Activation by Reducing I-κBα Degradation in Lymphoma Cells

(2012) Li Jia et al.   PLoS One

Antimalarial drug chloroquine counteracts activation of indoleamine (2,3)-dioxygenase activity in human PBMC

(2012) Johanna M. Gostner et al.   FEBS Open Bio

Akt and p53 are potential mediators of reduced mammary tumor growth by Chloroquine and the mTOR inhibitor RAD001

(2011) Christian R. Loehberg et al.   BIOCHEMICAL PHARMACOLOGY

Defective Regulation of Autophagy upon Leucine Deprivation Reveals a Targetable Liability of Human Melanoma Cells In Vitro and In Vivo

(2011) Joon-Ho Sheen et al.   CANCER CELL

The dynamic nature of autophagy in cancer

(2011) A. C. Kimmelman   GENES & DEVELOPMENT

Antitumor and antimetastatic activities of chloroquine diphosphate in a murine model of breast cancer

(2010) Pei-Du Jiang et al.   BIOMEDICINE & PHARMACOTHERAPY

Methods in Mammalian Autophagy Research

(2010) Noboru Mizushima et al.   CELL

Novel Cell- and Tissue-Based Assays for Detecting Misfolded and Aggregated Protein Accumulation Within Aggresomes and Inclusion Bodies

(2010) Dee Shen et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

Autophagy and the Integrated Stress Response

(2010) Guido Kroemer et al.   MOLECULAR CELL

Effect of autophagy on multiple myeloma cell viability

(2009) B. Hoang et al.   MOLECULAR CANCER THERAPEUTICS