Reactivation of a developmental Bmp2 signaling center is required for therapeutic control of the murine periosteal niche

A cytoplasmic role of Wnt/β-catenin transcriptional cofactors Bcl9, Bcl9l, and Pygopus in tooth enamel formation

(2017) Claudio Cantù et al.   Science Signaling

A cytoplasmic role of Wnt/β-catenin transcriptional cofactors Bcl9, Bcl9l, and Pygopus in tooth enamel formation

(2017) Claudio Cantù et al.   Science Signaling

Specification of osteoblast cell fate by canonical Wnt signaling requiresBmp2

(2016) Valerie S. Salazar et al.   DEVELOPMENT

Sp7/Osterix Is Restricted to Bone-Forming Vertebrates where It Acts as a Dlx Co-factor in Osteoblast Specification

(2016) Hironori Hojo et al.   DEVELOPMENTAL CELL

Use of teriparatide in osteoporotic fracture patients

(2016) Cory Collinge et al.   INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED

Skeletal effects of growth hormone and insulin-like growth factor-I therapy

(2016) Richard C. Lindsey et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

BMP signalling in skeletal development, disease and repair

(2016) Valerie S. Salazar et al.   Nature Reviews Endocrinology

Acute and Stress-related Injuries of Bone and Cartilage: Pertinent Anatomy, Basic Biomechanics, and Imaging Perspective

(2016) Mini N. Pathria et al.   RADIOLOGY

Distribution and clinical impact of functional variants in 50,726 whole-exome sequences from the DiscovEHR study

(2016) Frederick E. Dewey et al.   SCIENCE

Nosology and classification of genetic skeletal disorders: 2015 revision

(2015) Luisa Bonafe et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Dkk1 haploinsufficiency requires expression of Bmp2 for bone anabolic activity

(2015) Giuseppe Intini et al.   BONE

Second-generation PLINK: rising to the challenge of larger and richer datasets

(2015) Christopher C Chang et al.   GigaScience

The loss of activating transcription factor 4 (ATF4) reduces bone toughness and fracture toughness

(2014) Alexander J. Makowski et al.   BONE

Wnt-induced transcriptional activation is exclusively mediated by TCF/LEF

(2014) Jurian Schuijers et al.   EMBO JOURNAL

Fracture healing: mechanisms and interventions

(2014) Thomas A. Einhorn et al.   Nature Reviews Rheumatology

The Pygo2-H3K4me2/3 interaction is dispensable for mouse development and Wnt signaling-dependent transcription

(2013) C. Cantu et al.   DEVELOPMENT

Embryonic ablation of osteoblast Smad4 interrupts matrix synthesis in response to canonical Wnt signaling and causes an osteogenesis-imperfecta-like phenotype

(2013) V. S. Salazar et al.   JOURNAL OF CELL SCIENCE

Systematic comparison of phenome-wide association study of electronic medical record data and genome-wide association study data

(2013) Joshua C Denny et al.   NATURE BIOTECHNOLOGY

WNT signaling in bone homeostasis and disease: from human mutations to treatments

(2013) Roland Baron et al.   NATURE MEDICINE

Periosteal BMP2 activity drives bone graft healing

(2012) Vivianne Chappuis et al.   BONE

Sclerostin and Dickkopf-1 as Therapeutic Targets in Bone Diseases

(2012) Hua Zhu Ke et al.   ENDOCRINE REVIEWS

Osterix Regulates Calcification and Degradation of Chondrogenic Matrices through Matrix Metalloproteinase 13 (MMP13) Expression in Association with Transcription Factor Runx2 during Endochondral Ossification

(2012) Riko Nishimura et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

BMP3 Suppresses Osteoblast Differentiation of Bone Marrow Stromal Cells via Interaction with Acvr2b

(2011) Shoichiro Kokabu et al.   MOLECULAR ENDOCRINOLOGY

Transcriptional Regulation of BMP2 Expression by the PTH-CREB Signaling Pathway in Osteoblasts

(2011) Rongrong Zhang et al.   PLoS One

ID family protein expression and regulation in hypoxic pulmonary hypertension

(2010) Jonathan W. Lowery et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

PheWAS: demonstrating the feasibility of a phenome-wide scan to discover gene-disease associations

(2010) J. C. Denny et al.   BIOINFORMATICS

Suppression of Wnt Signaling by Dkk1 Attenuates PTH-Mediated Stromal Cell Response and New Bone Formation

(2010) Jun Guo et al.   Cell Metabolism

Osteoblast Precursors, but Not Mature Osteoblasts, Move into Developing and Fractured Bones along with Invading Blood Vessels

(2010) Christa Maes et al.   DEVELOPMENTAL CELL

Responsiveness of clonal limb bud cell lines to bone morphogenetic protein 2 reveals a sequential relationship between cartilage and bone cell phenotypes

(2010) Vicki Rosen et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Blockade of receptor-activated Gi signaling in osteoblasts in vivo leads to site-specific increases in cortical and cancellous bone formation

(2010) Susan M Millard et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Double disruption of α2A- and α2C -adrenoceptors results in sympathetic hyperactivity and high-bone-mass phenotype

(2010) Tatiana L Fonseca et al.   JOURNAL OF BONE AND MINERAL RESEARCH

The periosteum: what is it, where is it, and what mimics it in its absence?

(2010) Jerry R. Dwek   SKELETAL RADIOLOGY

BMP canonical Smad signaling through Smad1 and Smad5 is required for endochondral bone formation

(2009) K. N. Retting et al.   DEVELOPMENT

Overexpression of BMP3 in the developing skeleton alters endochondral bone formation resulting in spontaneous rib fractures

(2009) Laura W. Gamer et al.   DEVELOPMENTAL DYNAMICS

Parathyroid hormone (PTH)–induced bone gain is blunted in SOST overexpressing and deficient mice

(2009) Ina Kramer et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Real time monitoring of BMP Smads transcriptional activity during mouse development

(2008) Rui M. Monteiro et al.   GENESIS

Visualizing the lateral somitic frontier in the Prx1Cre transgenic mouse

(2008) J. Logan Durland et al.   JOURNAL OF ANATOMY