Catalytic Strategies to Convert 2‐Halopyridines to 2‐Alkylpyridines

Ni-catalyzed Reductive Liebeskind-Srogl Alkylation of Heterocycles

(2019) Yuanhong Ma et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic Strategy for Regioselective Arylethylamine Synthesis

(2019) Allyson J. Boyington et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Thorpe-Ingold Effect in Branch-Selective Alkylation of Unactivated Aryl Fluorides

(2018) Matthew J. O'Neill et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Barbier-Negishi Coupling of Secondary Alkyl Bromides with Aryl and Alkenyl Triflates and Nonaflates

(2018) Ke-Feng Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Transient imines as ‘next generation’ directing groups for the catalytic functionalisation of C–H bonds in a single operation

(2018) Sahra St John-Campbell et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

sp3 C–H activation via exo-type directing groups

(2018) Yan Xu et al.   Chemical Science

Modular Functionalization of Arenes in a Triply Selective Sequence: Rapid C(sp2 ) and C(sp3 ) Coupling of C−Br, C−OTf, and C−Cl Bonds Enabled by a Single Palladium(I) Dimer

(2018) Sinead T. Keaveney et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Direct arylation of strong aliphatic C–H bonds

(2018) Ian B. Perry et al.   NATURE

Radical Hydroarylation of Functionalized Olefins and Mechanistic Investigation of Photocatalytic Pyridyl Radical Reactions

(2018) Ciaran P. Seath et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Xantphos as a Branch-Selective Ligand for the Acyclic sec-Alkyl Negishi Cross-Coupling of Heteroaryl Halides

(2018) Alan H. Cherney et al.   ORGANOMETALLICS

Coupling of Challenging Heteroaryl Halides with Alkyl Halides via Nickel-Catalyzed Cross-Electrophile Coupling

(2017) Eric C. Hansen et al.   JOURNAL OF ORGANIC CHEMISTRY

Anti-Markovnikov Hydroarylation of Unactivated Olefins via Pyridyl Radical Intermediates

(2017) Allyson J. Boyington et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ru/Ni Dual Catalytic Desulfinative Photoredox Csp2–Csp3 Cross-Coupling of Alkyl Sulfinate Salts and Aryl Halides

(2017) Thomas Knauber et al.   ORGANIC LETTERS

A mild catalytic system for radical conjugate addition of nitrogen heterocycles

(2017) R. A. Aycock et al.   Chemical Science

A practical and scalable system for heteroaryl amino acid synthesis

(2017) R. A. Aycock et al.   Chemical Science

Photoredox-Mediated Routes to Radicals: The Value of Catalytic Radical Generation in Synthetic Methods Development

(2017) Jennifer K. Matsui et al.   ACS Catalysis

Well-defined nickel and palladium precatalysts for cross-coupling

(2017) Nilay Hazari et al.   Nature Reviews Chemistry

Single-Electron Transmetalation via Photoredox/Nickel Dual Catalysis: Unlocking a New Paradigm for sp3–sp2 Cross-Coupling

(2016) John C. Tellis et al.   ACCOUNTS OF CHEMICAL RESEARCH

Terminal-Selective Functionalization of Alkyl Chains by Regioconvergent Cross-Coupling

(2016) Stéphanie Dupuy et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Palladium-Catalyzed Transformations of Alkyl C–H Bonds

(2016) Jian He et al.   CHEMICAL REVIEWS

Pd-PEPPSI-IHeptCl: A General-Purpose, Highly Reactive Catalyst for the Selective Coupling of Secondary Alkyl Organozincs

(2016) Bruce Atwater et al.   CHEMISTRY-A EUROPEAN JOURNAL

Photoredox Catalysis in Organic Chemistry

(2016) Megan H. Shaw et al.   JOURNAL OF ORGANIC CHEMISTRY

Silyl Radical Activation of Alkyl Halides in Metallaphotoredox Catalysis: A Unique Pathway for Cross-Electrophile Coupling

(2016) Patricia Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Selective and Serial Suzuki–Miyaura Reactions of Polychlorinated Aromatics with Alkyl Pinacol Boronic Esters

(2016) Sébastien Laulhé et al.   ORGANIC LETTERS

Recent Developments in Negishi Cross-Coupling Reactions

(2016) Diana Haas et al.   ACS Catalysis

1,4-Dihydropyridines as Alkyl Radical Precursors: Introducing the Aldehyde Feedstock to Nickel/Photoredox Dual Catalysis

(2016) Álvaro Gutiérrez-Bonet et al.   ACS Catalysis

Recent advances in iron-catalysed cross coupling reactions and their mechanistic underpinning

(2016) T. L. Mako et al.   Inorganic Chemistry Frontiers

Methods and Mechanisms for Cross-Electrophile Coupling of Csp2 Halides with Alkyl Electrophiles

(2015) Daniel J. Weix   ACCOUNTS OF CHEMICAL RESEARCH

An Improved System for the Aqueous Lipshutz-Negishi Cross-Coupling of Alkyl Halides with Aryl Electrophiles

(2015) Vasudev R. Bhonde et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Iron-catalyzed cross-coupling of heteroaromatic tosylates with alkyl and aryl Grignard reagents

(2015) Xu Chen et al.   APPLIED ORGANOMETALLIC CHEMISTRY

Enantioselective and Enantiospecific Transition-Metal-Catalyzed Cross-Coupling Reactions of Organometallic Reagents To Construct C–C Bonds

(2015) Alan H. Cherney et al.   CHEMICAL REVIEWS

Base-Free Photoredox/Nickel Dual-Catalytic Cross-Coupling of Ammonium Alkylsilicates

(2015) Matthieu Jouffroy et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Configurationally stable, enantioenriched organometallic nucleophiles in stereospecific Pd-catalyzed cross-coupling reactions: an alternative approach to asymmetric synthesis

(2015) Chao-Yuan Wang et al.   Chemical Science

The Stille Reaction, 38 Years Later

(2015) Carlos Cordovilla et al.   ACS Catalysis

Rings in Drugs

(2014) Richard D. Taylor et al.   JOURNAL OF MEDICINAL CHEMISTRY

Reductive Cross-Coupling of Nonaromatic, Heterocyclic Bromides with Aryl and Heteroaryl Bromides

(2014) Gary A. Molander et al.   JOURNAL OF ORGANIC CHEMISTRY

N-Substituted 2-Aminobiphenylpalladium Methanesulfonate Precatalysts and Their Use in C–C and C–N Cross-Couplings

(2014) Nicholas C. Bruno et al.   JOURNAL OF ORGANIC CHEMISTRY

Recent advances in homogeneous nickel catalysis

(2014) Sarah Z. Tasker et al.   NATURE

Highly Selective Palladium-Catalyzed Cross-Coupling of Secondary Alkylzinc Reagents with Heteroaryl Halides

(2014) Yang Yang et al.   ORGANIC LETTERS

Single-electron transmetalation in organoboron cross-coupling by photoredox/nickel dual catalysis

(2014) J. C. Tellis et al.   SCIENCE

Merging photoredox with nickel catalysis: Coupling of  -carboxyl sp3-carbons with aryl halides

(2014) Z. Zuo et al.   SCIENCE

Nickel-Catalyzed Reductive Alkylation of Halogenated Pyridines with Secondary Alkyl Bromides

(2014) Huiyan Liu et al.   SYNTHETIC COMMUNICATIONS

An overview of the synthetic routes to the best selling drugs containing 6-membered heterocycles

(2013) Marcus Baumann et al.   Beilstein Journal of Organic Chemistry

Selection of boron reagents for Suzuki–Miyaura coupling

(2013) Alastair J. J. Lennox et al.   CHEMICAL SOCIETY REVIEWS

Mild Negishi Cross-Coupling Reactions Catalyzed by Acenaphthoimidazolylidene Palladium Complexes at Low Catalyst Loadings

(2013) Zelong Liu et al.   JOURNAL OF ORGANIC CHEMISTRY

Mechanism and Selectivity in Nickel-Catalyzed Cross-Electrophile Coupling of Aryl Halides with Alkyl Halides

(2013) Soumik Biswas et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Stereoretentive Pd-catalysed Stille cross-coupling reactions of secondary alkyl azastannatranes and aryl halides

(2013) Ling Li et al.   Nature Chemistry

Chemoselective sp2-sp3 Cross-Couplings: Iron-Catalyzed Alkyl Transfer to Dihaloaromatics

(2013) Sushant Malhotra et al.   ORGANIC LETTERS

Review. Regioselective Functionalization of Pyridines using a Directed Metalation or a Halogen/Metal Exchange

(2013) Sophia M. Manolikakes et al.   ZEITSCHRIFT FUR NATURFORSCHUNG SECTION B-A JOURNAL OF CHEMICAL SCIENCES

A General Solution for the 2-Pyridyl Problem

(2012) Graham R. Dick et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Palladium-Catalyzed Cross-Coupling: A Historical Contextual Perspective to the 2010 Nobel Prize

(2012) Carin C. C. Johansson Seechurn et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Suzuki–Miyaura Cross-Coupling of Potassium Alkoxyethyltrifluoroborates: Access to Aryl/Heteroarylethyloxy Motifs

(2012) Nicolas Fleury-Brégeot et al.   JOURNAL OF ORGANIC CHEMISTRY

Stereospecific Cross-Coupling of Secondary Organotrifluoroborates: Potassium 1-(Benzyloxy)alkyltrifluoroborates

(2012) Gary A. Molander et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Iron-Catalyzed Alkylations of Aryl Sulfamates and Carbamates

(2012) Amanda L. Silberstein et al.   ORGANIC LETTERS

Potassium Boc-Protected Secondary Aminomethyltrifluoroborates: Synthesis and Suzuki–Miyaura Cross-Coupling Reactions

(2012) Gary A. Molander et al.   ORGANIC LETTERS

Nickel-Catalyzed Reductive Coupling of Aryl Halides with Secondary Alkyl Bromides and Allylic Acetate

(2012) Shulin Wang et al.   ORGANIC LETTERS

Design and preparation of new palladium precatalysts for C–C and C–N cross-coupling reactions

(2012) Nicholas C. Bruno et al.   Chemical Science

Advances in Transition Metal (Pd,Ni,Fe)-Catalyzed Cross-Coupling Reactions Using Alkyl-organometallics as Reaction Partners

(2011) Ranjan Jana et al.   CHEMICAL REVIEWS

N-Heterocyclic carbene (NHC) ligands and palladium in homogeneous cross-coupling catalysis: a perfect union

(2011) George C. Fortman et al.   CHEMICAL SOCIETY REVIEWS

Pd- and Ni-Catalyzed Cross-Coupling Reactions of Functionalized Organozinc Reagents with Unsaturated Thioethers

(2011) Laurin Melzig et al.   CHEMISTRY-A EUROPEAN JOURNAL

Direct Aminoalkylation of Arenes, Heteroarenes, and Alkenes via Ni-Catalyzed Negishi Cross-Coupling Reactions

(2011) Laurin Melzig et al.   JOURNAL OF ORGANIC CHEMISTRY

Synthesis and Suzuki–Miyaura Cross-Coupling Reactions of Potassium Boc-Protected Aminomethyltrifluoroborate with Aryl and Hetaryl Halides

(2011) Gary A. Molander et al.   ORGANIC LETTERS

Metal-Catalyzed α-Arylation of Carbonyl and Related Molecules: Novel Trends in CC Bond Formation by CH Bond Functionalization

(2010) Carin C. C. Johansson et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Structure-Activity Relationship Analysis of Pd-PEPPSI Complexes in Cross-Couplings: A Close Inspection of the Catalytic Cycle and the Precatalyst Activation Model

(2010) Joanna Nasielski et al.   CHEMISTRY-A EUROPEAN JOURNAL

Room Temperature Cross-Coupling of Highly Functionalized Organozinc Reagents with ThiomethylatedN-Heterocycles by Nickel Catalysis

(2010) Laurin Melzig et al.   JOURNAL OF ORGANIC CHEMISTRY

Nickel-Catalyzed Reductive Cross-Coupling of Aryl Halides with Alkyl Halides

(2010) Daniel A. Everson et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A New Palladium Precatalyst Allows for the Fast Suzuki−Miyaura Coupling Reactions of Unstable Polyfluorophenyl and 2-Heteroaryl Boronic Acids

(2010) Tom Kinzel et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis of Amidomethyltrifluoroborates and Their Use in Cross-Coupling Reactions

(2010) Gary A. Molander et al.   ORGANIC LETTERS

Transition Metal-Catalyzed Direct Arylation of Substrates with Activated sp3-Hybridized C−H Bonds and Some of Their Synthetic Equivalents with Aryl Halides and Pseudohalides

(2009) Fabio Bellina et al.   CHEMICAL REVIEWS

Theoretical Bond Dissociation Energies of Halo-Heterocycles: Trends and Relationships to Regioselectivity in Palladium-Catalyzed Cross-Coupling Reactions

(2009) Yeimy Garcia et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Pd-Catalyzed Cross-Coupling of Functionalized Organozinc Reagents with Thiomethyl-Substituted Heterocycles

(2009) Albrecht Metzger et al.   ORGANIC LETTERS

Palladium-Catalyzed Suzuki−Miyaura Cross-Coupling Reactions Employing Dialkylbiaryl Phosphine Ligands

(2008) Ruben Martin et al.   ACCOUNTS OF CHEMICAL RESEARCH

The Promise and Challenge of Iron-Catalyzed Cross Coupling

(2008) Benjamin D. Sherry et al.   ACCOUNTS OF CHEMICAL RESEARCH