A Comprehensive Assessment of Apigenin as an Antiproliferative, Proapoptotic, Antiangiogenic and Immunomodulatory Phytocompound

Apigenin: A dietary flavonoid with diverse anticancer properties

(2018) Josip Madunić et al.   CANCER LETTERS

Panax ginseng Polysaccharide Protected H9c2 Cardiomyocyte From Hypoxia/Reoxygenation Injury Through Regulating Mitochondrial Metabolism and RISK Pathway

(2018) Yi-Han Zuo et al.   Frontiers in Physiology

Botanical Therapeutics: Phytochemical Screening and Biological Assessment of Chamomile, Parsley and Celery Extracts against A375 Human Melanoma and Dendritic Cells

(2018) Corina Danciu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Phytochemical Characterization and Evaluation of the Antimicrobial, Antiproliferative and Pro-Apoptotic Potential of Ephedra alata Decne. Hydroalcoholic Extract against the MCF-7 Breast Cancer Cell Line

(2018) Corina Danciu et al.   MOLECULES

Apigenin: A current review on its beneficial biological activities

(2017) Xiang Zhou et al.   JOURNAL OF FOOD BIOCHEMISTRY

Nuclear Translocation of SGPP-1 and Decrease of SGPL-1 Activity Contribute to Sphingolipid Rheostat Regulation of Inflammatory Dendritic Cells

(2017) Anja Schwiebs et al.   MEDIATORS OF INFLAMMATION

Apigenin inhibits proliferation and invasion, and induces apoptosis and cell cycle arrest in human melanoma cells

(2017) Guangming Zhao et al.   ONCOLOGY REPORTS

Standardization of A375 human melanoma models on chicken embryo chorioallantoic membrane and Balb/c nude mice

(2017) Stefana Avram et al.   ONCOLOGY REPORTS

Apigenin in cancer therapy: anti-cancer effects and mechanisms of action

(2017) Xiaohui Yan et al.   Cell and Bioscience

Apigenin suppresses the senescence-associated secretory phenotype and paracrine effects on breast cancer cells

(2017) Kevin M. Perrott et al.   GeroScience

Selective Toxicity of Apigenin on Cancerous Hepatocytes by Directly Targeting their Mitochondria

(2016) Enayatollah Seydi et al.   Anti-Cancer Agents in Medicinal Chemistry

The immune system

(2016) L. B. Nicholson   Essays in Biochemistry

The Role of Natural Polyphenols in the Prevention and Treatment of Cervical Cancer—An Overview

(2016) Marius Moga et al.   MOLECULES

Inhibition of the STAT3 signaling pathway contributes to apigenin-mediated anti-metastatic effect in melanoma

(2016) Hui-Hui Cao et al.   Scientific Reports

Apigenin Attenuates Melanoma Cell Migration by Inducing Anoikis through Integrin and Focal Adhesion Kinase Inhibition

(2015) Md. Hasnat et al.   MOLECULES

Curcumin and Apigenin - novel and promising therapeutics against chronic neuroinflammation in Alzheimer′s disease

(2015) Gerald Münch et al.   Neural Regeneration Research

Plant Flavone Apigenin Binds to Nucleic Acid Bases and Reduces Oxidative DNA Damage in Prostate Epithelial Cells

(2014) Haripaul Sharma et al.   PLoS One

Antitumor immune responses mediated by dendritic cells: How signals derived from dying cancer cells drive antigen cross-presentation

(2014) Lotte Spel et al.   OncoImmunology

A chorioallantoic membrane model for the determination of anti-angiogenic effects of imatinib

(2013) Aybike Özcetin et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Subtoxic Levels of Apigenin Inhibit Expression and Secretion of VEGF by Uveal Melanoma Cells via Suppression of ERK1/2 and PI3K/Akt Pathways

(2013) Shih-Chun Chao et al.   Evidence-based Complementary and Alternative Medicine

Apigenin-induced apoptosis in A375 and A549 cells through selective action and dysfunction of mitochondria

(2013) Sreemanti Das et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Increasing Melanoma—Too Many Skin Cell Damages or Too Few Repairs?

(2013) Örjan Hallberg et al.   Cancers

Apigenin induces apoptosis via tumor necrosis factor receptor- and Bcl-2-mediated pathway and enhances susceptibility of head and neck squamous cell carcinoma to 5-fluorouracil and cisplatin

(2012) Leong-Perng Chan et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Identification and Analysis of the Active Phytochemicals from the Anti-Cancer Botanical Extract Bezielle

(2012) Vivian Chen et al.   PLoS One

Definition of the “Drug-Angiogenic-Activity-Index” that Allows the Quantification of the Positive and Negative Angiogenic Active Drugs: A Study Based on the Chorioallantoic Membrane Model

(2011) Resit Demir et al.   PATHOLOGY & ONCOLOGY RESEARCH

A Simple Protocol for Using a LDH-Based Cytotoxicity Assay to Assess the Effects of Death and Growth Inhibition at the Same Time

(2011) Shilo M. Smith et al.   PLoS One

Bioenergetic Profile Experiment using C2C12 Myoblast Cells

(2010) David G. Nicholls et al.   Jove-Journal of Visualized Experiments

Apigenin Induces Apoptosis through a Mitochondria/Caspase-Pathway in Human Breast Cancer MDA-MB-453 Cells

(2009) Eun Jeong Choi et al.   JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION

Natural compounds for cancer treatment and prevention

(2009) Stefania Nobili et al.   PHARMACOLOGICAL RESEARCH