Antitumor immune responses mediated by dendritic cells: How signals derived from dying cancer cells drive antigen cross-presentation

NADPH oxidases contribute to autophagy regulation

(2014) Ju Huang et al.   Autophagy

Antigen Persistence Is Required for Dendritic Cell Licensing and CD8+ T Cell Cross-Priming

(2014) H. Jusforgues-Saklani et al.   JOURNAL OF IMMUNOLOGY

Cancer immunoediting: antigens, mechanisms, and implications to cancer immunotherapy

(2013) Matthew D. Vesely et al.   Annals of the New York Academy of Sciences

Similar antigen cross-presentation capacity and phagocytic functions in all freshly isolated human lymphoid organ–resident dendritic cells

(2013) Elodie Segura et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Invariant NKT Cells Induce Plasmacytoid Dendritic Cell (DC) Cross-Talk with Conventional DCs for Efficient Memory CD8+ T Cell Induction

(2013) K. Shimizu et al.   JOURNAL OF IMMUNOLOGY

Antigen cross-presentation by dendritic cell subsets: one general or all sergeants?

(2013) Stefan Nierkens et al.   TRENDS IN IMMUNOLOGY

Immunogenic Cell Death in Cancer Therapy

(2012) Guido Kroemer et al.   Annual Review of Immunology

Fc  receptor antigen targeting potentiates cross-presentation by human blood and lymphoid tissue BDCA-3+ dendritic cells

(2012) T. W. H. Flinsenberg et al.   BLOOD

Noncanonical Autophagy Is Required for Type I Interferon Secretion in Response to DNA-Immune Complexes

(2012) Jill Henault et al.   IMMUNITY

The Dendritic Cell Receptor Clec9A Binds Damaged Cells via Exposed Actin Filaments

(2012) Jian-Guo Zhang et al.   IMMUNITY

The dendritic cell receptor DNGR-1 controls endocytic handling of necrotic cell antigens to favor cross-priming of CTLs in virus-infected mice

(2012) Santiago Zelenay et al.   JOURNAL OF CLINICAL INVESTIGATION

Induction of Type I IFN Is a Physiological Immune Reaction to Apoptotic Cell-Derived Membrane Microparticles

(2012) M. Schiller et al.   JOURNAL OF IMMUNOLOGY

TLR Agonists Stimulate Nlrp3-Dependent IL-1  Production Independently of the Purinergic P2X7 Receptor in Dendritic Cells and In Vivo

(2012) Y. He et al.   JOURNAL OF IMMUNOLOGY

Deciphering the transcriptional network of the dendritic cell lineage

(2012) Jennifer C Miller et al.   NATURE IMMUNOLOGY

Assessment of Roles for Calreticulin in the Cross-Presentation of Soluble and Bead-Associated Antigens

(2012) Natasha Del Cid et al.   PLoS One

Development of antigen cross-presentation capacity in dendritic cells

(2012) Christiane Dresch et al.   TRENDS IN IMMUNOLOGY

The Role of Heat Shock Proteins in Antigen Cross Presentation

(2012) Ayesha Murshid et al.   Frontiers in Immunology

Primary sterile necrotic cells fail to cross-prime CD8+T cells

(2012) Jaba Gamrekelashvili et al.   OncoImmunology

IFN-  enhances cross-presentation in human dendritic cells by modulating antigen survival, endocytic routing, and processing

(2011) F. Spadaro et al.   BLOOD

Immune Adjuvant Efficacy of CpG Oligonucleotide in Cancer Treatment Is Founded Specifically upon TLR9 Function in Plasmacytoid Dendritic Cells

(2011) S. Nierkens et al.   CANCER RESEARCH

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

CD103+pulmonary dendritic cells preferentially acquire and present apoptotic cell–associated antigen

(2011) A. Nicole Desch et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Type I interferon is selectively required by dendritic cells for immune rejection of tumors

(2011) Mark S. Diamond et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A Critical Role for Granzymes in Antigen Cross-Presentation through Regulating Phagocytosis of Killed Tumor Cells

(2011) S. Hoves et al.   JOURNAL OF IMMUNOLOGY

Type I IFNs Control Antigen Retention and Survival of CD8 + Dendritic Cells after Uptake of Tumor Apoptotic Cells Leading to Cross-Priming

(2011) S. Lorenzi et al.   JOURNAL OF IMMUNOLOGY

Microtubule-associated protein 1 light chain 3 alpha (LC3)-associated phagocytosis is required for the efficient clearance of dead cells

(2011) J. Martinez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Secondary necrosis: The natural outcome of the complete apoptotic program

(2010) Manuel T. Silva   FEBS LETTERS

Human CD141+(BDCA-3)+dendritic cells (DCs) represent a unique myeloid DC subset that cross-presents necrotic cell antigens

(2010) Sarah L. Jongbloed et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Found in translation: the human equivalent of mouse CD8+dendritic cells: Table I.

(2010) Jose A. Villadangos et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Prolonged Antigen Storage Endows Merocytic Dendritic Cells with Enhanced Capacity To Prime Anti-Tumor Responses in Tumor-Bearing Mice

(2010) R. A. Reboulet et al.   JOURNAL OF IMMUNOLOGY

Molecular mechanisms of necroptosis: an ordered cellular explosion

(2010) Peter Vandenabeele et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Autophagy within the antigen donor cell facilitates efficient antigen cross-priming of virus-specific CD8+ T cells

(2009) M Uhl et al.   CELL DEATH AND DIFFERENTIATION

The Small GTPase Rac2 Controls Phagosomal Alkalinization and Antigen Crosspresentation Selectively in CD8+ Dendritic Cells

(2009) Ariel Savina et al.   IMMUNITY

Direct Antigen Presentation and Gap Junction Mediated Cross-Presentation during Apoptosis

(2009) B. Pang et al.   JOURNAL OF IMMUNOLOGY

Identification of a dendritic cell receptor that couples sensing of necrosis to immunity

(2009) David Sancho et al.   NATURE

Activation of the NLRP3 inflammasome in dendritic cells induces IL-1β–dependent adaptive immunity against tumors

(2009) François Ghiringhelli et al.   NATURE MEDICINE

Antigen storage compartments in mature dendritic cells facilitate prolonged cytotoxic T lymphocyte cross-priming capacity

(2009) N. van Montfoort et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

NADPH oxidase controls phagosomal pH and antigen cross-presentation in human dendritic cells

(2008) A. R. Mantegazza et al.   BLOOD

Whole lymphoma B cells allow efficient cross-presentation of antigens by dendritic cells

(2008) O. Manches et al.   CYTOTHERAPY

CLEC9A Is a Novel Activation C-type Lectin-like Receptor Expressed on BDCA3+Dendritic Cells and a Subset of Monocytes

(2008) Cristal Huysamen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tumor therapy in mice via antigen targeting to a novel, DC-restricted C-type lectin

(2008) David Sancho et al.   JOURNAL OF CLINICAL INVESTIGATION

Post-apoptotic tumors are more palatable to dendritic cells and enhance their antigen cross-presentation activity

(2008) Davide Brusa et al.   VACCINE